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Journal of Cardiothoracic Surgery

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Open Access 01-12-2023 | Echocardiography | Research

Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure

Author: Yongxia Zhang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

Abstract

Background

Chronic heart failure (CHF) is regarded as common clinical heart disease. This study aims to investigate the clinical diagnostic value of echocardiography (Echo) and serum C-reactive protein (CRP) levels in patients with CHF.

Methods

A total of 75 patients with CHF (42 males, 33 females, age 62.72 ± 1.06 years) were enrolled as study subjects, with 70 non-CHF subjects (38 males, 32 females, age 62.44 ± 1.28 years) as controls. The left ventricular ejection fraction (LVEF), fraction shortening rate of the left ventricle (FS), and early to late diastolic filling (E/A) were determined by Echo, followed by an examination of the expression of serum CRP by ELISA. In addition, the Pearson method was used to analyze the correlation between echocardiographic quantitative parameters (EQPs) (LVEF, FS, and E/A) and serum CRP levels. Receiver operating characteristic (ROC) curve was adopted to evaluate the diagnostic efficacy of EQPs and serum CRP levels for CHF. The independent risk factors for CHF patients were measured by logistics regression analysis.

Results

The serum CRP level of CHF patients was elevated, the values of LVEF and FS decreased, and the E/A values increased. ROC curve revealed that the EQPs (LVEF, FS, and E/A) combined with serum CRP had high diagnostic values for CHF patients. Logistic regression analysis showed that the EQPs (LVEF, FS, and E/A) and serum CRP levels were independent risk factors for CHF patients.

Conclusion

Echo combined with serum CRP level has high clinical diagnostic values for CHF patients.

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Title: Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
Author: Yongxia Zhang
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Echocardiography
Heart Failure
Echocardiography
Chronic Heart Failure
Published in: Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-023-02176-7

2024 ASCO Annual Meeting

Springer Medicine

Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure

Abstract

Background

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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