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Intensive Care Medicine

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01-09-2015 | Correspondence

Early goal-directed therapy in the treatment of sepsis: response to comments by Jaehne et al.

Authors: Derek Angus, Sandra Peake, Kathy Rowan, on behalf of the ARISE, ProCESS and ProMISe Investigators

Published in: Intensive Care Medicine | Issue 9/2015

Excerpt

Dear Editor, …

Jaehne AK, Salem D, Garces JD (2015) Early goal-directed therapy in the treatment of sepsis: the times have changed but not the therapy and benefit to patients. Intensive Care Med. doi:10.1007/s00134-015-3927-6 PubMed

Angus DC, Barnato AE, Bell D, Bellomo R, Chong C-R, Coats TJ, Davies A, Delaney A, Harrison DA, Holdgate A, Howe B, Huang DT, Iwashyna T, Kellum JA, Peake SL, Pike F, Reade MC, Rowan KM, Singer Webb SAR, Weissfeld LA, Yealy D, Young JD (2015) A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISE Investigators. Intensive Care Med. doi:10.1007/s00134-015-3822-1

Rivers E, Nguyen B, Havstad S, Ressler J, Muxzzasin A, Knoblich B, Peterson E, Tomlanovich M (2001) Early goal-directed therapy collaborative group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377CrossRefPubMed

The ARISE Investigators, the ANZICS Clinical Trials Group (2014) Goal-directed resuscitation for patients with early septic shock. N Engl J Med 371:1496–1506CrossRef

The ProCESS Investigators (2014) A randomized trial of protocol-based care for early septic shock. N Engl J Med 370:1683–1693PubMedCentralCrossRef

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RG, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM, Investigators ProMISe Trial (2015) The protocolised management in sepsis (ProMISe) trial. N Engl J Med 372:1301–1311CrossRefPubMed

Sjoding MW, Luo K, Miller MA, Iwashyna TJ (2015) When do confounding by indication and inadequate risk adjustment bias critical care studies? A simulation study. Crit Care 19:195PubMedCentralCrossRefPubMed

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R, Surviving Sepsis Campaign Guidelines Committee including The Paediatric Subgroup (2012) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock. Intensive Care Med 39:165–228CrossRef

Title: Early goal-directed therapy in the treatment of sepsis: response to comments by Jaehne et al.
Authors: Derek Angus
Sandra Peake
Kathy Rowan
on behalf of the ARISE, ProCESS and ProMISe Investigators
Publication date: 01-09-2015
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 9/2015
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-015-3943-6

At a glance: The STEP trials

Springer Medicine

Early goal-directed therapy in the treatment of sepsis: response to comments by Jaehne et al.

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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