Published in:
01-02-2004 | Poster presentation
Early and aggressive use of high-dose norepinephrine in the treatment of septic shock
Authors:
A Kapralou, D Theodorou, P Drimousis, F Archondovassilis, K Stamou, C Mpantias, G Karantzikos, S Katsaragakis
Published in:
Critical Care
|
Special Issue 1/2004
Login to get access
Excerpt
Hyperdynamic circulation of septic shock is characterized in the hyperdynamic phase by increased cardiac output and decreased peripheral vascular resistance, and consequently low pressure. The use of norepinephrine as a pure vasoconstrictor aims to increase vascular resistance and blood pressure. There is a subgroup of patients with septic shock that does not respond to usual or high doses of norepinephrine. Usually in these patients different therapeutic approaches are used. In this study, we try to evaluate the role of very high doses of norepinephrine (≥ 2 μg/kg/min) in the treatment of septic shock. …
