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Child's Nervous System
Published in: Child's Nervous System 3/2024

17-11-2023 | Dystonia | Review

Intraventricular baclofen for palliative management of acquired generalized dystonia in pediatric patients: a case series and literature review

Authors: M. Krouma, A. Aboudou Soilhi, B. Desnous, S. James, C. Boulay, D. Scavarda

Published in: Child's Nervous System | Issue 3/2024

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Abstract

Dystonia represents a significant source of disability in children. Generalized dystonia, which involves multiple body regions, leads to impaired mobility and motor function, resulting in substantial challenges in daily activities. Surgical treatments are used when medical treatments fail. Intrathecal baclofen (ITB) or deep brain stimulations (DBS) are the most employed surgical therapies. When these options are not feasible or ineffective, some authors have explored the use of intraventricular baclofen (IVB). In this report, we present four cases of pediatric patients with generalized dystonia who underwent treatment with IVB, resulting in notable improvements. To further explore the potential of this treatment modality, we conducted a comprehensive literature review. The findings from our study provide a comprehensive overview that can guide palliative management in similar cases.
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Metadata
Title
Intraventricular baclofen for palliative management of acquired generalized dystonia in pediatric patients: a case series and literature review
Authors
M. Krouma
A. Aboudou Soilhi
B. Desnous
S. James
C. Boulay
D. Scavarda
Publication date
17-11-2023
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 3/2024
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-023-06217-3

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