Top

General Thoracic and Cardiovascular Surgery

Published in:

01-04-2021 | Dyspnea | Case Report

A rare case of primary angiosarcoma of the anterior mediastinum

Authors: Kazuhiro Yamazaki, Kenji Minakata, Takeichiro Nakane, Hideyuki Kinoshita, Kiminobu Tanizawa, Shinji Sumiyoshi, Hiroki Sato, Kenji Minatoya, Ryuzo Sakata

Published in: General Thoracic and Cardiovascular Surgery | Issue 4/2021

Abstract

A 32-year-old male patient was initially diagnosed with fibrosing mediastinitis. The patient subsequently developed severe dyspnea and was further diagnosed with constrictive pericarditis due to the extent of fibrosing mediastinitis around the heart. Therefore, the patient underwent surgical resection of the fibrotic tissue in the anterior mediastinum including the pericardium and the pleura. Postoperative histological and immunohistochemical analyses revealed angiosarcoma. Seven years after the diagnosis, he is still alive. Herein, we report a case of atypical primary angiosarcoma of the anterior mediastinum causing constrictive pericarditis and restrictive pulmonary dysfunction.

Togashi Y, Kim YH, Miyahara R, et al. Octreotide, a somatostatin analogue, in the treatment of chylothorax associated with idiopathic fibrosing mediastinitis. Tohoku J Exp Med. 2010;222:51–3.CrossRef

Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ. Angiosarcoma. Lancet Oncol. 2010;11:983–91.CrossRef

Dainese E, Pozzi B, Milani M, et al. Primary pleural epidermoid angiosarcoma. A case report and review of literature. Pathol Res Pract. 2010;206:415–9.CrossRef

Weissferdt A, Kalhor N, Suster S, Moran CA. Primary angiosarcoma of the anterior mediastinum: a clinicopathologic and immunohistochemical study of 9 cases. Hum Pathol. 2010;41:1711–7.CrossRef

Fayette J, Martin E, Piperno-Neumann S, et al. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases. Ann Oncol. 2007;18:2030–6.CrossRef

Anderson T, Zhang L, Hameed M, Rushch V, Travis WD, Antonescu CR. Thoracic epithelioid malignant vascular tumors: a clinicopathorogic study of 52 cases with emphasis on pathologic grading and molecular studies of WWTR1-CAMTA1 fusions. Am J Surg Pathol. 2015;39:132–9.CrossRef

Title: A rare case of primary angiosarcoma of the anterior mediastinum
Authors: Kazuhiro Yamazaki
Kenji Minakata
Takeichiro Nakane
Hideyuki Kinoshita
Kiminobu Tanizawa
Shinji Sumiyoshi
Hiroki Sato
Kenji Minatoya
Ryuzo Sakata
Publication date: 01-04-2021
Publisher: Springer Singapore
Keywords: Dyspnea
Dyspnea
Mediastinitis
Mediastinitis
Published in: General Thoracic and Cardiovascular Surgery / Issue 4/2021
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI: https://doi.org/10.1007/s11748-020-01551-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A rare case of primary angiosarcoma of the anterior mediastinum

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2021

Syphilitic aortitis: chronic left coronary ostial occlusion and aortic regurgitation with aortitis

Do meteorological factors influence the occurrence of acute aortic dissection? A 10-year retrospective institutional study

Long-term clinical follow-up after lung transplantation in patient with scoliosis: a case report

A successful surgical tracheobronchoplasty in a case of expiratory collapse of central airways associated with tracheobronchomalacia in a severely deformed single lung patient

Status of pleural lavage cytology in cases of pulmonary metastasis: a single-institution retrospective study

Negative impact of chemical pleurodesis on postoperative pulmonary function for managing prolonged air leakage after segmentectomy