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Published in: Indian Journal of Pediatrics 1/2011

01-01-2011 | Original Article

Dyslipidemia amongst Obese Children in National Capital Territory (NCT) of Delhi

Authors: Supreet Kaur, Umesh Kapil

Published in: Indian Journal of Pediatrics | Issue 1/2011

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Abstract

Objective

Childhood obesity is associated with unfavorable lipid profile. Obese children have increased risk of development of coronary heart disease (CHD) in adult life. There is lack of data on association of dyslipidemia with obesity in children from India, hence, the present investigation was undertaken.

Methods

Study was conducted in NCT of Delhi. Thirty schools in each of the 3 socio economic groups i.e., LIG, MIG and HIG were selected. From each school, 170 children were included in the survey. A total of 16,585 children were studied. Anthropometric measurements of weight and height were taken using standard methodology Four hundred and fifty one obese children (cases) were identified using IOTF classification. Equal number of children, matched for age, sex and socio-economic status, with optimal body weight were selected as control. The blood samples were collected for lipid profile estimation. Same investigations were undertaken, both in cases and controls.

Results

In obese children, mean total cholesterol, triglyceride and LDL-C levels were significantly higher as compared to their matched controls (p < 0.001). BMI was significantly correlated with lipid profile.

Conclusions

Obesity amongst children was associated with unfavorable lipid profile.
Literature
1.
go back to reference Castelli WP, Garrison MS, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. Incidence of coronary heart diseases and lipoprotein cholesterol levels: the Framingham study. JAMA. 1986;256:2835–8.CrossRefPubMed Castelli WP, Garrison MS, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. Incidence of coronary heart diseases and lipoprotein cholesterol levels: the Framingham study. JAMA. 1986;256:2835–8.CrossRefPubMed
2.
go back to reference Lauer RM, Lee J, Clarke WR. Factors affecting the relationship between childhood and adult cholesterol levels: the Muscatine study. Pediatrics. 1988;82:309–18.PubMed Lauer RM, Lee J, Clarke WR. Factors affecting the relationship between childhood and adult cholesterol levels: the Muscatine study. Pediatrics. 1988;82:309–18.PubMed
3.
go back to reference Garcia RE, Moodie DS. Routine cholesterol surveillance in childhood. Pediatrics. 1989;84:751–5.PubMed Garcia RE, Moodie DS. Routine cholesterol surveillance in childhood. Pediatrics. 1989;84:751–5.PubMed
4.
go back to reference Wong ND, Bassin S, Deitrick R. Relationship of blood lipids to body composition and family medical history in an ethnically diverse school aged population. Ethn Dis. 1991;1:351–63.PubMed Wong ND, Bassin S, Deitrick R. Relationship of blood lipids to body composition and family medical history in an ethnically diverse school aged population. Ethn Dis. 1991;1:351–63.PubMed
5.
go back to reference Davidson DM, VanCamp J, Iftner CA, Landry SM, Bradley BJ, Wong ND. Family history fails to detect the majority of children with high capillary blood total cholesterol. J Sch Health. 1991;61:75–80.CrossRefPubMed Davidson DM, VanCamp J, Iftner CA, Landry SM, Bradley BJ, Wong ND. Family history fails to detect the majority of children with high capillary blood total cholesterol. J Sch Health. 1991;61:75–80.CrossRefPubMed
6.
go back to reference Cole JC, Mary CB, Katherine MF, William HD. Establishing a standard definition for child overweight and obesity worldwide: international survey. Br Med J. 2000;320:1240–3.CrossRef Cole JC, Mary CB, Katherine MF, William HD. Establishing a standard definition for child overweight and obesity worldwide: international survey. Br Med J. 2000;320:1240–3.CrossRef
7.
go back to reference WHO. Physical status: The use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organisation Technical Report Series 854. Geneva: WHO; 1995. p. 427–30. WHO. Physical status: The use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organisation Technical Report Series 854. Geneva: WHO; 1995. p. 427–30.
8.
go back to reference Friewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of preparative ultra centrifuge. Clin Chem. 1972;18:499–502. Friewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of preparative ultra centrifuge. Clin Chem. 1972;18:499–502.
9.
go back to reference National Cholesterol Education Program. Report of the expert panel on blood cholesterol levels in children and adolescents. Pediatrics. 1992;89:525–84. National Cholesterol Education Program. Report of the expert panel on blood cholesterol levels in children and adolescents. Pediatrics. 1992;89:525–84.
10.
go back to reference Garces C, Guisado GJ, Benavente M et al. Obesity in Spanish school children: relationship with lipid profile and insulin resistance. Obes Res. 2005;13:959–63.CrossRefPubMed Garces C, Guisado GJ, Benavente M et al. Obesity in Spanish school children: relationship with lipid profile and insulin resistance. Obes Res. 2005;13:959–63.CrossRefPubMed
11.
go back to reference Dubey S, Kabra M, Bajpai A et al. Serum leptin levels in obese Indian children: relation to clinical and biochemical parameters. Indian Pediatr. 2007;44:257–62.PubMed Dubey S, Kabra M, Bajpai A et al. Serum leptin levels in obese Indian children: relation to clinical and biochemical parameters. Indian Pediatr. 2007;44:257–62.PubMed
12.
go back to reference Mitra A, Singh S, Devidayal, Khullar M. Serum lipids in north Indian children treated for Kawasaki disease. Int Heart J. 2005;46:811–7.CrossRefPubMed Mitra A, Singh S, Devidayal, Khullar M. Serum lipids in north Indian children treated for Kawasaki disease. Int Heart J. 2005;46:811–7.CrossRefPubMed
13.
go back to reference Chu NF, Rimm EB, Wang DJ, Liou HS, Shieh SM. Clustering of cardiovascular disease risk factors among obese school children: the Taipei children heart study. Am J Clin Nutr. 1998;67:1141–6.PubMed Chu NF, Rimm EB, Wang DJ, Liou HS, Shieh SM. Clustering of cardiovascular disease risk factors among obese school children: the Taipei children heart study. Am J Clin Nutr. 1998;67:1141–6.PubMed
14.
go back to reference Semiz S, Ozgoren E, Sabir N, Semiz E. Body fat distribution in childhood obesity: association with metabolic risk factors. Indian Pediatr. 2008;45:457–62.PubMed Semiz S, Ozgoren E, Sabir N, Semiz E. Body fat distribution in childhood obesity: association with metabolic risk factors. Indian Pediatr. 2008;45:457–62.PubMed
15.
go back to reference Friedland O, Memet D, Gorodnitsky N, Wolach BM, Eliakim A. Obesity and lipid profile in children and adolescents. J Pediatr Endocrinol Metab. 2002;15:1011–6.PubMed Friedland O, Memet D, Gorodnitsky N, Wolach BM, Eliakim A. Obesity and lipid profile in children and adolescents. J Pediatr Endocrinol Metab. 2002;15:1011–6.PubMed
16.
go back to reference Kelishadi R, Pour MH, Sarraf-Zadegan N et al. Obesity and associated modifiable environment factors in Iranian adolescents: Isfahan healthy program-heart health promotion from childhood. Pediatr Int. 2003;45:435–42.CrossRefPubMed Kelishadi R, Pour MH, Sarraf-Zadegan N et al. Obesity and associated modifiable environment factors in Iranian adolescents: Isfahan healthy program-heart health promotion from childhood. Pediatr Int. 2003;45:435–42.CrossRefPubMed
17.
go back to reference Vizcaino VM, Aguilar FS, Martinez MS, Lopez MS, Gutierrez RF, Rodriguez-Artalejo F. Association of adiposity measures with blood lipids and blood pressure in children aged 8–11 years. Acta Pediatr. 2007;96:1338–42.CrossRef Vizcaino VM, Aguilar FS, Martinez MS, Lopez MS, Gutierrez RF, Rodriguez-Artalejo F. Association of adiposity measures with blood lipids and blood pressure in children aged 8–11 years. Acta Pediatr. 2007;96:1338–42.CrossRef
Metadata
Title
Dyslipidemia amongst Obese Children in National Capital Territory (NCT) of Delhi
Authors
Supreet Kaur
Umesh Kapil
Publication date
01-01-2011
Publisher
Springer-Verlag
Published in
Indian Journal of Pediatrics / Issue 1/2011
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-010-0263-2

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