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BMC Gastroenterology
Published in: BMC Gastroenterology 1/2010

Open Access 01-12-2010 | Case report

Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective

Authors: Peter T Kalogerinis, John E Poulos, Andrew Morfesis, Anthony Daniels, Stavroula Georgakila, Thomas Daignualt, Alexandros G Georgakilas

Published in: BMC Gastroenterology | Issue 1/2010

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Abstract

Background

There is very small occurrence of adenocarcinoma in the small bowel. We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the molecular biology behind small bowel neoplasms and treatment options.

Case

The patient had a history of iron deficiency anemia and occult bleeding with extensive workup consisting of upper endoscopy, colonoscopy, capsule endoscopy, upper gastrointestinal series with small bowel follow through and push enteroscopy. Due to persistent abdominal pain and iron deficiency anemia the patient underwent push enteroscopy which revealed adenocarcinoma of the duodenum. The patient underwent en-bloc duodenectomy which revealed T3N1M0 adenocarcinoma of the 4th portion of the duodenum.

Conclusions

Primary duodenal carcinoma, although rare should be considered in the differential diagnosis of occult gastrointestinal bleeding when evaluation of the lower and upper GI tract is unremarkable. We discuss the current evaluation and management of this small bowel neoplasm.
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Metadata
Title
Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective
Authors
Peter T Kalogerinis
John E Poulos
Andrew Morfesis
Anthony Daniels
Stavroula Georgakila
Thomas Daignualt
Alexandros G Georgakilas
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2010
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/1471-230X-10-109

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