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01-01-2008 | Editorial

Duloxetine as a treatment for stress incontinence—where are we now?

Author: Jonathan Duckett

Published in: International Urogynecology Journal | Issue 1/2008

Excerpt

Duloxetine was introduced with a series of publications, expert reviews and marketing activity in 2004. It was the first licensed drug for the treatment of stress incontinence. A series of placebo randomised controlled trials were conducted in markets all over the world [1‐4]. Pooled results showed that duloxetine was more effective than placebo in treating stress incontinence [5]. A Cochrane review came to the conclusion that duloxetine reduced the frequency of incontinence episodes and improved quality of life scores [6]. Tolerability rates and success seemed good. Surgeons felt slightly threatened that their services would be no longer required. Duloxetine was initially widely approved and licensed in over 30 countries [7]. Duloxetine was incorporated into the treatment algorithm for stress incontinence adopted by the International Continence Society (ICS) [8]. Has duloxetine lived up to our expectations? …

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Title: Duloxetine as a treatment for stress incontinence—where are we now?
Author: Jonathan Duckett
Publication date: 01-01-2008
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 1/2008
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-007-0463-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Duloxetine as a treatment for stress incontinence—where are we now?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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