Published in:
01-11-2015 | Original Article
Doppler flowmetry of the superior mesenteric artery and portal vein: impact for the early prediction of necrotizing enterocolitis in neonates
Authors:
Ausra Urboniene, Arvydas Palepsaitis, Rimantas Uktveris, Vidmantas Barauskas
Published in:
Pediatric Surgery International
|
Issue 11/2015
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Abstract
Purpose
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder in newborns. Early diagnosis and rapid treatment is essential for seeking good outcome for neonates. The aim of our study was to evaluate intestinal blood flow in superior mesenteric artery (SMA) and portal vein (PV) in neonates with suspected or confirmed NEC and investigate the prognostic cut-off values to develop NEC.
Methods
Doppler flowmetry of SMA and PV was performed for 62 newborns. Resistive (RI) and pulsatility (PI) indexes were measured in SMA as well as Volumetric blood flow (Vflow) in PV. ROC curves were applied to estimate sensitivity and specificity and to identify cut-off values.
Results
There were 93.5 % preterm neonates. 29 patients (46.8 %) were diagnosed with NEC and 33 (53.2 %) formed a control group. 96.3 % NEC patients had RI >0.75 with sensitivity of 96.3 % and specificity of 90.9 % (OR 260). 88.9 % NEC patients had PI >1.85 with sensitivity of 88.9 % and specificity of 78.8 % (OR 29). Portal Vflow lower than 37 ml/min was present in 89.7 % patients with NEC (OR 11.7).
Conclusion
Intestinal blood flow Dopplerography can be a useful tool for diagnosing and predicting NEC.