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Published in: Pediatric Surgery International 11/2015

01-11-2015 | Original Article

Doppler flowmetry of the superior mesenteric artery and portal vein: impact for the early prediction of necrotizing enterocolitis in neonates

Authors: Ausra Urboniene, Arvydas Palepsaitis, Rimantas Uktveris, Vidmantas Barauskas

Published in: Pediatric Surgery International | Issue 11/2015

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Abstract

Purpose

Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder in newborns. Early diagnosis and rapid treatment is essential for seeking good outcome for neonates. The aim of our study was to evaluate intestinal blood flow in superior mesenteric artery (SMA) and portal vein (PV) in neonates with suspected or confirmed NEC and investigate the prognostic cut-off values to develop NEC.

Methods

Doppler flowmetry of SMA and PV was performed for 62 newborns. Resistive (RI) and pulsatility (PI) indexes were measured in SMA as well as Volumetric blood flow (Vflow) in PV. ROC curves were applied to estimate sensitivity and specificity and to identify cut-off values.

Results

There were 93.5 % preterm neonates. 29 patients (46.8 %) were diagnosed with NEC and 33 (53.2 %) formed a control group. 96.3 % NEC patients had RI >0.75 with sensitivity of 96.3 % and specificity of 90.9 % (OR 260). 88.9 % NEC patients had PI >1.85 with sensitivity of 88.9 % and specificity of 78.8 % (OR 29). Portal Vflow lower than 37 ml/min was present in 89.7 % patients with NEC (OR 11.7).

Conclusion

Intestinal blood flow Dopplerography can be a useful tool for diagnosing and predicting NEC.
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Metadata
Title
Doppler flowmetry of the superior mesenteric artery and portal vein: impact for the early prediction of necrotizing enterocolitis in neonates
Authors
Ausra Urboniene
Arvydas Palepsaitis
Rimantas Uktveris
Vidmantas Barauskas
Publication date
01-11-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 11/2015
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-015-3792-y

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