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Open Access 01-09-2010 | Basic Neurosciences, Genetics and Immunology - Short Communication

Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?

Authors: S. Oreland, L. Daoura, L. Gustafsson-Ericson, M. Damberg, P. Hyytiä, L. Oreland, Ingrid Nylander

Published in: Journal of Neural Transmission | Issue 9/2010

Abstract

Genes involved in alcoholism have consensus sites for the transcription factor activator protein (TFAP) 2β. In the present study, we investigated TFAP-2β protein levels in the ethanol-preferring alko, alcohol (AA) and the ethanol-avoiding alko, non-alcohol (ANA) rat lines. Furthermore, basal and ethanol-induced TFAP-2β levels were examined in Wistar rats exposed to different early postnatal environments that are known to affect later ethanol consumption. Taken together, we found differences in brainstem TFAP-2β protein between the AA and ANA rats.

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Title: Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
Authors: S. Oreland
L. Daoura
L. Gustafsson-Ericson
M. Damberg
P. Hyytiä
L. Oreland
Ingrid Nylander
Publication date: 01-09-2010
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 9/2010
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-010-0448-x

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Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?

Abstract

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Abstract

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