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Published in: Obesity Surgery 2/2016

01-02-2016 | Original Contributions

Does Preincisional Infiltration with Bupivacaine Reduce Postoperative Pain in Laparoscopic Bariatric Surgery?

Authors: Rafael Moncada, Linas Martinaitis, Manuel Landecho, Fernando Rotellar, Carlos Sanchez-Justicia, Manuel Bellver, Magdalena de la Higuera, Camilo Silva, Beatriz Osés, Elena Martín, Susana Pérez, Jose Luis Hernandez-Lizoain, Gema Frühbeck, Victor Valentí

Published in: Obesity Surgery | Issue 2/2016

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Abstract

Background

Current evidence suggests that local anesthetic wound infiltration should be employed as part of multimodal postoperative pain management. There is scarce data concerning the benefits of this anesthetic modality in laparoscopic weight loss surgery. Therefore, we analyzed the influence of trocar site infiltration with bupivacaine on the management of postoperative pain in laparoscopic bariatric surgery.

Methods

This retrospective randomized study included 47 patients undergoing primary obesity surgery between January and September 2014. Laparoscopic gastric bypass was performed in 39 cases and sleeve gastrectomy in 8 cases. Patients were stratified into two groups depending on whether preincisional infiltration with bupivacaine and epinephrine was performed (study group, 27 patients) or not (control group, 20 patients). Visual analogue scale (VAS), International Pain Outcomes questionnaire, and rescue medication records were reviewed to assess postoperative pain.

Results

VAS scores in the study group and sleeve gastrectomy group were lower than those in the control and gastric bypass groups in the first 4 h postoperatively without reaching statistical significance (p > 0.05). VAS scores did not differ in any other period of time. No statistically significant differences in pain perception were registered according to the patient’s pain outcomes questionnaire or the need for rescue medication.

Conclusions

The present study did not conclusively prove the efficacy of bupivacaine infiltration by any of the three evaluation methods analyzed. Nevertheless, preincisional infiltration provides good level of comfort in the immediate postoperative period when analgesia is most urgent.
Literature
1.
go back to reference Schumann R. Anaesthesia for bariatric surgery. Best Pract Res Clin Anaesthesiol. 2011;25(1):83–93.PubMedCrossRef Schumann R. Anaesthesia for bariatric surgery. Best Pract Res Clin Anaesthesiol. 2011;25(1):83–93.PubMedCrossRef
2.
go back to reference Schumann R, Jones SB, Ortiz VE, et al. Best practice recommendations for anesthetic perioperative care and pain management in weight loss surgery. Obes Res. 2005;13(2):254–66.PubMedCrossRef Schumann R, Jones SB, Ortiz VE, et al. Best practice recommendations for anesthetic perioperative care and pain management in weight loss surgery. Obes Res. 2005;13(2):254–66.PubMedCrossRef
3.
go back to reference Lamvu G, Zolnoun D, Boggess J, et al. Obesity: physiologic changes and challenges during laparoscopy. Am J Obstet Gynecol. 2004;191(2):669–74.PubMedCrossRef Lamvu G, Zolnoun D, Boggess J, et al. Obesity: physiologic changes and challenges during laparoscopy. Am J Obstet Gynecol. 2004;191(2):669–74.PubMedCrossRef
4.
go back to reference Levi D, Goodman ER, Patel M, et al. Critical care of the obese and bariatric surgical patient. Crit Care Clin. 2003;19(1):11–32.PubMedCrossRef Levi D, Goodman ER, Patel M, et al. Critical care of the obese and bariatric surgical patient. Crit Care Clin. 2003;19(1):11–32.PubMedCrossRef
5.
go back to reference Korolija D, Sauerland S, Wood-Dauphinee S, et al. Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the european association for endoscopic surgery. Surg Endosc. 2004;18(6):879–97.PubMedCrossRef Korolija D, Sauerland S, Wood-Dauphinee S, et al. Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the european association for endoscopic surgery. Surg Endosc. 2004;18(6):879–97.PubMedCrossRef
6.
go back to reference Kaye AD, Ali SI, Urman RD. Perioperative analgesia: ever-changing technology and pharmacology. Best Pract Res Clin Anaesthesiol. 2014;28(1):3–14.PubMedCrossRef Kaye AD, Ali SI, Urman RD. Perioperative analgesia: ever-changing technology and pharmacology. Best Pract Res Clin Anaesthesiol. 2014;28(1):3–14.PubMedCrossRef
7.
go back to reference Palmer PP, Royal MA, Miller RD. Novel delivery systems for postoperative analgesia. Best Pract Res Clin Anaesthesiol. 2014;28(1):81–90.PubMedCrossRef Palmer PP, Royal MA, Miller RD. Novel delivery systems for postoperative analgesia. Best Pract Res Clin Anaesthesiol. 2014;28(1):81–90.PubMedCrossRef
8.
go back to reference Banks A. Innovations in postoperative pain management: continuous infusion of local anesthetics. AORN J. 2007;85(5):904. 14; quiz 915–8.PubMedCrossRef Banks A. Innovations in postoperative pain management: continuous infusion of local anesthetics. AORN J. 2007;85(5):904. 14; quiz 915–8.PubMedCrossRef
9.
go back to reference Gupta A. Local anaesthesia for pain relief after laparoscopic cholecystectomy—a systematic review. Best Pract Res Clin Anaesthesiol. 2005;19(2):275–92.PubMedCrossRef Gupta A. Local anaesthesia for pain relief after laparoscopic cholecystectomy—a systematic review. Best Pract Res Clin Anaesthesiol. 2005;19(2):275–92.PubMedCrossRef
10.
go back to reference Pavlidis TE, Atmatzidis KS, Papaziogas BT, et al. The effect of preincisional periportal infiltration with ropivacaine in pain relief after laparoscopic procedures: a prospective, randomized controlled trial. JSLS. 2003;7(4):305–10.PubMedPubMedCentral Pavlidis TE, Atmatzidis KS, Papaziogas BT, et al. The effect of preincisional periportal infiltration with ropivacaine in pain relief after laparoscopic procedures: a prospective, randomized controlled trial. JSLS. 2003;7(4):305–10.PubMedPubMedCentral
11.
go back to reference Gerges FJ, Kanazi GE, Jabbour-Khoury SI. Anesthesia for laparoscopy: a review. J Clin Anesth. 2006;18(1):67–78.PubMedCrossRef Gerges FJ, Kanazi GE, Jabbour-Khoury SI. Anesthesia for laparoscopy: a review. J Clin Anesth. 2006;18(1):67–78.PubMedCrossRef
12.
go back to reference El Hachem L, Small E, Chung P, et al. Randomized controlled double-blind trial of transversus abdominis plane block versus trocar site infiltration in gynecologic laparoscopy. Am J Obstet Gynecol. 2014. El Hachem L, Small E, Chung P, et al. Randomized controlled double-blind trial of transversus abdominis plane block versus trocar site infiltration in gynecologic laparoscopy. Am J Obstet Gynecol. 2014.
13.
go back to reference Cottam DR, Fisher B, Atkinson J, et al. A randomized trial of bupivicaine pain pumps to eliminate the need for patient controlled analgesia pumps in primary laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2007;17(5):595–600.PubMedCrossRef Cottam DR, Fisher B, Atkinson J, et al. A randomized trial of bupivicaine pain pumps to eliminate the need for patient controlled analgesia pumps in primary laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2007;17(5):595–600.PubMedCrossRef
14.
go back to reference NIH conference. gastrointestinal surgery for severe obesity. consensus development conference panel. Ann Intern Med. 1991;115(12):956–61. NIH conference. gastrointestinal surgery for severe obesity. consensus development conference panel. Ann Intern Med. 1991;115(12):956–61.
16.
go back to reference Gordon DB, Polomano RC, Pellino TA, et al. Revised american pain society patient outcome questionnaire (APS-POQ-R) for quality improvement of pain management in hospitalized adults: preliminary psychometric evaluation. J Pain. 2010;11(11):1172–86.PubMedCrossRef Gordon DB, Polomano RC, Pellino TA, et al. Revised american pain society patient outcome questionnaire (APS-POQ-R) for quality improvement of pain management in hospitalized adults: preliminary psychometric evaluation. J Pain. 2010;11(11):1172–86.PubMedCrossRef
17.
go back to reference Wu CL, Cohen SR, Richman JM, et al. Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysis. Anesthesiology. 2005;103(5):1079,88; quiz 1109–10. Wu CL, Cohen SR, Richman JM, et al. Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysis. Anesthesiology. 2005;103(5):1079,88; quiz 1109–10.
18.
go back to reference Kehlet H, Liu SS. Continuous local anesthetic wound infusion to improve postoperative outcome: back to the periphery? Anesthesiology. 2007;107(3):369–71.PubMedCrossRef Kehlet H, Liu SS. Continuous local anesthetic wound infusion to improve postoperative outcome: back to the periphery? Anesthesiology. 2007;107(3):369–71.PubMedCrossRef
20.
go back to reference Coughlin SM, Karanicolas PJ, Emmerton-Coughlin HM, et al. Better late than never? Impact of local analgesia timing on postoperative pain in laparoscopic surgery: a systematic review and metaanalysis. Surg Endosc. 2010;24(12):3167–76.PubMedCrossRef Coughlin SM, Karanicolas PJ, Emmerton-Coughlin HM, et al. Better late than never? Impact of local analgesia timing on postoperative pain in laparoscopic surgery: a systematic review and metaanalysis. Surg Endosc. 2010;24(12):3167–76.PubMedCrossRef
21.
go back to reference Lee IO, Kim SH, Kong MH, et al. Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine. Can J Anaesth. 2001;48(6):545–50.PubMedCrossRef Lee IO, Kim SH, Kong MH, et al. Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine. Can J Anaesth. 2001;48(6):545–50.PubMedCrossRef
22.
go back to reference Mullender A, Melichar G, Schmucker P, et al. Psychological traits, course of surgery and recovery following hernia repair in patients preferring general or local anaesthesia. Anaesthesist. 2006;55(3):247–54.PubMedCrossRef Mullender A, Melichar G, Schmucker P, et al. Psychological traits, course of surgery and recovery following hernia repair in patients preferring general or local anaesthesia. Anaesthesist. 2006;55(3):247–54.PubMedCrossRef
23.
go back to reference Anantanarayanan P, Raja DK, Kumar JN, et al. Catheter-based donor site analgesia after rib grafting: a prospective, randomized, double-blinded clinical trial comparing ropivacaine and bupivacaine. J Oral Maxillofac Surg. 2013;71(1):29–34.PubMedCrossRef Anantanarayanan P, Raja DK, Kumar JN, et al. Catheter-based donor site analgesia after rib grafting: a prospective, randomized, double-blinded clinical trial comparing ropivacaine and bupivacaine. J Oral Maxillofac Surg. 2013;71(1):29–34.PubMedCrossRef
24.
go back to reference Lklouk M, Ismail K. Intra-operative fentanyl gives superior pain relief for patients undergoing laparoscopic bariatric surgery when compared to morphine: 14AP4-6. Eur J Anaesthesiol. 2014;31:225.CrossRef Lklouk M, Ismail K. Intra-operative fentanyl gives superior pain relief for patients undergoing laparoscopic bariatric surgery when compared to morphine: 14AP4-6. Eur J Anaesthesiol. 2014;31:225.CrossRef
25.
go back to reference Sherwinter DA, Ghaznavi AM, Spinner D, et al. Continuous infusion of intraperitoneal bupivacaine after laparoscopic surgery: a randomized controlled trial. Obes Surg. 2008;18(12):1581–6.PubMedCrossRef Sherwinter DA, Ghaznavi AM, Spinner D, et al. Continuous infusion of intraperitoneal bupivacaine after laparoscopic surgery: a randomized controlled trial. Obes Surg. 2008;18(12):1581–6.PubMedCrossRef
26.
go back to reference Symons JL, Kemmeter PR, Davis AT, et al. A double-blinded, prospective randomized controlled trial of intraperitoneal bupivacaine in laparoscopic roux-en-Y gastric bypass. J Am Coll Surg. 2007;204(3):392–8.PubMedCrossRef Symons JL, Kemmeter PR, Davis AT, et al. A double-blinded, prospective randomized controlled trial of intraperitoneal bupivacaine in laparoscopic roux-en-Y gastric bypass. J Am Coll Surg. 2007;204(3):392–8.PubMedCrossRef
27.
go back to reference Alkhamesi NA, Kane JM, Guske PJ, et al. Intraperitoneal aerosolization of bupivacaine is a safe and effective method in controlling postoperative pain in laparoscopic Roux-en-Y gastric bypass. J Pain Res. 2008;1:9–13.PubMedPubMedCentralCrossRef Alkhamesi NA, Kane JM, Guske PJ, et al. Intraperitoneal aerosolization of bupivacaine is a safe and effective method in controlling postoperative pain in laparoscopic Roux-en-Y gastric bypass. J Pain Res. 2008;1:9–13.PubMedPubMedCentralCrossRef
28.
go back to reference De Oliveira GS, Duncan Jr K, Fitzgerald P, et al. Systemic lidocaine to improve quality of recovery after laparoscopic bariatric surgery: a randomized double-blinded placebo-controlled trial. Obes Surg. 2014;24(2):212–8.PubMedCrossRef De Oliveira GS, Duncan Jr K, Fitzgerald P, et al. Systemic lidocaine to improve quality of recovery after laparoscopic bariatric surgery: a randomized double-blinded placebo-controlled trial. Obes Surg. 2014;24(2):212–8.PubMedCrossRef
29.
go back to reference Sinha A, Jayaraman L, Punhani D. Efficacy of ultrasound-guided transversus abdominis plane block after laparoscopic bariatric surgery: a double blind, randomized, controlled study. Obes Surg. 2013;23(4):548–53.PubMedCrossRef Sinha A, Jayaraman L, Punhani D. Efficacy of ultrasound-guided transversus abdominis plane block after laparoscopic bariatric surgery: a double blind, randomized, controlled study. Obes Surg. 2013;23(4):548–53.PubMedCrossRef
30.
go back to reference Andersen LP, Werner MU, Rosenberg J, et al. Analgesic treatment in laparoscopic gastric bypass surgery: a systematic review of randomized trials. Obes Surg. 2014;24(3):462–70.PubMedCrossRef Andersen LP, Werner MU, Rosenberg J, et al. Analgesic treatment in laparoscopic gastric bypass surgery: a systematic review of randomized trials. Obes Surg. 2014;24(3):462–70.PubMedCrossRef
31.
go back to reference Tong YC, Kaye AD, Urman RD. Liposomal bupivacaine and clinical outcomes. Best Pract Res Clin Anaesthesiol. 2014;28(1):15–27.PubMedCrossRef Tong YC, Kaye AD, Urman RD. Liposomal bupivacaine and clinical outcomes. Best Pract Res Clin Anaesthesiol. 2014;28(1):15–27.PubMedCrossRef
32.
go back to reference Hu D, Onel E, Singla N, et al. Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site. Clin Drug Investig. 2013;33(2):109–15.PubMedCrossRef Hu D, Onel E, Singla N, et al. Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site. Clin Drug Investig. 2013;33(2):109–15.PubMedCrossRef
33.
go back to reference Bertin PM. Liposome bupivacaine for postsurgical pain in an obese woman with chronic pain undergoing laparoscopic gastrectomy: a case report. J Med Case Rep. 2014;8:21,1947-8-21.CrossRef Bertin PM. Liposome bupivacaine for postsurgical pain in an obese woman with chronic pain undergoing laparoscopic gastrectomy: a case report. J Med Case Rep. 2014;8:21,1947-8-21.CrossRef
Metadata
Title
Does Preincisional Infiltration with Bupivacaine Reduce Postoperative Pain in Laparoscopic Bariatric Surgery?
Authors
Rafael Moncada
Linas Martinaitis
Manuel Landecho
Fernando Rotellar
Carlos Sanchez-Justicia
Manuel Bellver
Magdalena de la Higuera
Camilo Silva
Beatriz Osés
Elena Martín
Susana Pérez
Jose Luis Hernandez-Lizoain
Gema Frühbeck
Victor Valentí
Publication date
01-02-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 2/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1761-0

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