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Published in: Clinical Oral Investigations 2/2019

01-02-2019 | Original Article

Does enamel matrix derivative application improve clinical outcomes after semilunar flap surgery? A randomized clinical trial

Authors: Isabela Lima França-Grohmann, João Paulo Menck Sangiorgio, Manuela Rocha Bueno, Renato Corrêa Viana Casarin, Karina Gonzáles Silvério, Francisco Humberto Nociti Jr, Márcio Zaffalon Casati, Enilson Antonio Sallum

Published in: Clinical Oral Investigations | Issue 2/2019

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Abstract

Objectives

To evaluate the treatment of gingival recessions by semilunar coronally positioned flap plus enamel matrix derivative (SCPF + EMD).

Materials and methods

Thirty patients with class I localized gingival recession were included. They were randomly allocated in two groups: SCPF + EMD and SCPF. Recession height (RH), recession width (RW), width of keratinized tissue (WKT), thickness of keratinized tissue (TKT), probing depth (PD), and clinical attachment level (CAL) were measured at baseline, 6 and 12 months post-surgery. Patient/professional evaluation of esthetics and root sensitivity was performed.

Results

After 12 months, mean root coverage was 1.98 ± 0.33 mm for SCPF + EMD (90.86 ± 14.69%) and 1.85 ± 0.41 mm (79.76 ± 17.44%) for SCPF (p > 0.05). The esthetic evaluation by the patient showed preference for SCPF + EMD. According to the professional evaluation (QCE), the use of EMD decreases the appearance of postoperative scar tissue line. There was a significant reduction in root hypersensitivity with no further complaints by the patients.

Conclusions

The addition of EMD provides significantly better esthetics to SCPF, according to patient and professional assessments. SCPF + EMD is effective but not superior to SCPF for root coverage, after 12 months.

Clinical relevance

Previous clinical trials showed that the combination of EMD with coronally advanced flaps may enhance the outcome of root coverage. There is a lack of studies testing the combination of EMD with SCPF. The combination SCPF + EMD provides better esthetics when compared to the SCPF and is effective, but not superior, to SCPF for root coverage, after 12 months.

Trial registration: NCT02459704

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Metadata
Title
Does enamel matrix derivative application improve clinical outcomes after semilunar flap surgery? A randomized clinical trial
Authors
Isabela Lima França-Grohmann
João Paulo Menck Sangiorgio
Manuela Rocha Bueno
Renato Corrêa Viana Casarin
Karina Gonzáles Silvério
Francisco Humberto Nociti Jr
Márcio Zaffalon Casati
Enilson Antonio Sallum
Publication date
01-02-2019
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 2/2019
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-018-2506-y

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