Skip to main content
Top
Published in: BMC Psychiatry 1/2007

Open Access 01-12-2007 | Research article

Does bright light have an anxiolytic effect? - an open trial

Authors: Shawn D Youngstedt, Daniel F Kripke

Published in: BMC Psychiatry | Issue 1/2007

Login to get access

Abstract

Background

The aim of this open trial was to examine the influence of acute bright light exposure on anxiety in older and young adults.

Methods

This study was ancillary to a complex 5-day laboratory experiment testing phase-responses to light at all times of the day. On 3 consecutive days, participants were exposed to bright light (3,000 lux) for 3 hours. The Spielberger State-Trait Anxiety Inventory (Form Y1) was administered 5 minutes before and 20 minutes after each treatment. Mean state anxiety before and after treatment were analyzed by age, sex, and time ANOVA. To avoid floor effects, only participants with baseline STAI levels of ≥ 25 were included.

Results

A significant anxiolytic effect of bright light was found for the mean data, as well as for each of the three days. No significant main effect of age, sex, or interaction of these factors with STAI change were found.

Conclusion

The results show consistent and significant (albeit modest) anxiolytic effects following acute bright light exposure in low anxiety adults. Further randomized, controlled trials in clinically anxious individuals are needed.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HO, Kendler KS: Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiat. 1994, 51: 8-19.CrossRefPubMed Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HO, Kendler KS: Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiat. 1994, 51: 8-19.CrossRefPubMed
2.
go back to reference Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK: The de facto US mental and addictive disorders service system : epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiat. 1993, 50: 85-94.CrossRefPubMed Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK: The de facto US mental and addictive disorders service system : epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiat. 1993, 50: 85-94.CrossRefPubMed
3.
go back to reference Balon R: Mood, anxiety, and physical illness: body and mind, or mind and body?. Depression Anxiety. 2006, 23: 377-87. 10.1002/da.20217.CrossRefPubMed Balon R: Mood, anxiety, and physical illness: body and mind, or mind and body?. Depression Anxiety. 2006, 23: 377-87. 10.1002/da.20217.CrossRefPubMed
4.
go back to reference Muller JE, Koen L, Stein DJ: Anxiety and medical disorders. Current Psychiat Rep. 2005, 7: 245-51. 10.1007/s11920-005-0077-5.CrossRef Muller JE, Koen L, Stein DJ: Anxiety and medical disorders. Current Psychiat Rep. 2005, 7: 245-51. 10.1007/s11920-005-0077-5.CrossRef
5.
go back to reference Scott KM, Bruffaerts R, Tsang A, Ormel J, Alonso J, Angermeyer MC, Benjet C, Bromet E, de Girolamo G, de Graaf R, Gasquet I, Gureye O, Haro JM, He Y, Kessler RC, Levinson D, Mneimnah ZN, Oakley Browne MA, Posada-Villa JA, Stein DJ, Takeshima T, Van Korff M: Depression-anxiety relationships with chronic physical conditions: Results from the World Mental Health surveys. J Affect Disord. 2007, 103 (1-3): 113-120. 10.1016/j.jad.2007.01.015.CrossRefPubMed Scott KM, Bruffaerts R, Tsang A, Ormel J, Alonso J, Angermeyer MC, Benjet C, Bromet E, de Girolamo G, de Graaf R, Gasquet I, Gureye O, Haro JM, He Y, Kessler RC, Levinson D, Mneimnah ZN, Oakley Browne MA, Posada-Villa JA, Stein DJ, Takeshima T, Van Korff M: Depression-anxiety relationships with chronic physical conditions: Results from the World Mental Health surveys. J Affect Disord. 2007, 103 (1-3): 113-120. 10.1016/j.jad.2007.01.015.CrossRefPubMed
6.
go back to reference Hoffman DL, Dukes EM, Wittchen HU: Human and economic burden of generalized anxiety disorder. Depress Anxiety. 2006, [Epub ahead of print], Hoffman DL, Dukes EM, Wittchen HU: Human and economic burden of generalized anxiety disorder. Depress Anxiety. 2006, [Epub ahead of print],
7.
go back to reference Sanderson K, Tilse E, Nicholson J, Oldenburg B, Graves N: Which presenteeism measures are more sensitive to depression and anxiety?. J Affect Disord. 2007, 101: 65-74. 10.1016/j.jad.2006.10.024.CrossRefPubMed Sanderson K, Tilse E, Nicholson J, Oldenburg B, Graves N: Which presenteeism measures are more sensitive to depression and anxiety?. J Affect Disord. 2007, 101: 65-74. 10.1016/j.jad.2006.10.024.CrossRefPubMed
8.
go back to reference Buffett-Jerrott SE, Stewart SH: Cognitive and sedative effects of benzodiazepine use. Curr Pharm Des. 2002, 8: 45-58. 10.2174/1381612023396654.CrossRefPubMed Buffett-Jerrott SE, Stewart SH: Cognitive and sedative effects of benzodiazepine use. Curr Pharm Des. 2002, 8: 45-58. 10.2174/1381612023396654.CrossRefPubMed
9.
go back to reference Beracochea D: Anterograde and retrograde effects of benzodiazepines on memory. ScientificWorldJournal. 2006, 6: 1460-1465. 10.1100/tsw.2006.243.CrossRefPubMed Beracochea D: Anterograde and retrograde effects of benzodiazepines on memory. ScientificWorldJournal. 2006, 6: 1460-1465. 10.1100/tsw.2006.243.CrossRefPubMed
10.
go back to reference Struzik L, Vermani M, Coonerty-Femiano A, Katzman MA: Treatments for generalized anxiety disorder. Expert Rev Neurotherapeut. 2004, 4: 285-94. 10.1586/14737175.4.2.285.CrossRef Struzik L, Vermani M, Coonerty-Femiano A, Katzman MA: Treatments for generalized anxiety disorder. Expert Rev Neurotherapeut. 2004, 4: 285-94. 10.1586/14737175.4.2.285.CrossRef
11.
go back to reference Segraves RT: Sexual side-effects of psychiatric drugs. Intl J Psychiatry Med. 1988, 18 (3): 243-252.CrossRef Segraves RT: Sexual side-effects of psychiatric drugs. Intl J Psychiatry Med. 1988, 18 (3): 243-252.CrossRef
12.
go back to reference Rosenthal NE, Sack DA, Carpenter CJ, Parry B, Mendelson WB, Wehr TA: Antidepressant effects of light in seasonal affective disorder. Am J Psychiat. 1985, 142: 163-70.CrossRefPubMed Rosenthal NE, Sack DA, Carpenter CJ, Parry B, Mendelson WB, Wehr TA: Antidepressant effects of light in seasonal affective disorder. Am J Psychiat. 1985, 142: 163-70.CrossRefPubMed
13.
14.
go back to reference Parry BL, Mahan AM, Mostofi N, Klauber MR, Lew GS, Gillin JC: Light therapy of late luteal phase dysphoric disorder : an extended study. Am J Psychiat. 1993, 150: 1417-385.CrossRefPubMed Parry BL, Mahan AM, Mostofi N, Klauber MR, Lew GS, Gillin JC: Light therapy of late luteal phase dysphoric disorder : an extended study. Am J Psychiat. 1993, 150: 1417-385.CrossRefPubMed
15.
go back to reference Terman M, Terman JS: Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects. CNS Spectrums. 2005, 10: 647-63.CrossRefPubMed Terman M, Terman JS: Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects. CNS Spectrums. 2005, 10: 647-63.CrossRefPubMed
16.
go back to reference Tuunainen A, Kripke DF, Endo T: Light therapy for non-seasonal depression. Cochrane Database Syst Rev. 2004, 2: CD004050-PubMed Tuunainen A, Kripke DF, Endo T: Light therapy for non-seasonal depression. Cochrane Database Syst Rev. 2004, 2: CD004050-PubMed
17.
go back to reference Epperson CN, Terman M, Terman JS, Hanusa BH, Oren DA, Peindl KS, Wisner KL: Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings. J Clin Psychiatry. 2004, 65 (3): 421-425.CrossRefPubMed Epperson CN, Terman M, Terman JS, Hanusa BH, Oren DA, Peindl KS, Wisner KL: Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings. J Clin Psychiatry. 2004, 65 (3): 421-425.CrossRefPubMed
18.
go back to reference Pollack MH: Comorbid anxiety and depression. J Clin Psychiatry. 2005, 66 (Suppl 8): 22-29.PubMed Pollack MH: Comorbid anxiety and depression. J Clin Psychiatry. 2005, 66 (Suppl 8): 22-29.PubMed
19.
go back to reference Sheehan DV, Eaddy MT, Shah MB, Mauch RP: Differences in total medical costs across the SSRIs for the treatment of depression and anxiety. Am J Manag Care. 2005, 11 (12 Suppl): S354-S361.PubMed Sheehan DV, Eaddy MT, Shah MB, Mauch RP: Differences in total medical costs across the SSRIs for the treatment of depression and anxiety. Am J Manag Care. 2005, 11 (12 Suppl): S354-S361.PubMed
20.
go back to reference Terman M: On the specific action and clinical domain of light treatment. Seasonal Affective Disorder and Beyond: Light Treatment for SAD and Non-SAD Conditions. Edited by: Lam RW. 1998, Washington, DC: American Psychiatric Press, Inc, 91-116. Terman M: On the specific action and clinical domain of light treatment. Seasonal Affective Disorder and Beyond: Light Treatment for SAD and Non-SAD Conditions. Edited by: Lam RW. 1998, Washington, DC: American Psychiatric Press, Inc, 91-116.
21.
go back to reference Partonen T, LÖnnqvist J: Bright light improves vitality and alleviates distress in healthy people. J Affect Disord. 2000, 57: 55-61. 10.1016/S0165-0327(99)00063-4.CrossRefPubMed Partonen T, LÖnnqvist J: Bright light improves vitality and alleviates distress in healthy people. J Affect Disord. 2000, 57: 55-61. 10.1016/S0165-0327(99)00063-4.CrossRefPubMed
22.
go back to reference Tam EM, Lam RW, Yatham LN, Zis AP: Psychobiological effects of light therapy in seasonal affective disorder. Seasonal Affective Disorder and Beyond: Light Treatment for SAD and Non-SAD Conditions. Edited by: Lam RW. 1998, Washington, DC: American Psychiatric Press, Inc, 117-42. Tam EM, Lam RW, Yatham LN, Zis AP: Psychobiological effects of light therapy in seasonal affective disorder. Seasonal Affective Disorder and Beyond: Light Treatment for SAD and Non-SAD Conditions. Edited by: Lam RW. 1998, Washington, DC: American Psychiatric Press, Inc, 117-42.
23.
go back to reference ACSM's Guidelines for Exercise Testing and Prescription. Edited by: Franklin BA. 2006, Philadelphia: Lippicott Williams & Wilkins ACSM's Guidelines for Exercise Testing and Prescription. Edited by: Franklin BA. 2006, Philadelphia: Lippicott Williams & Wilkins
24.
go back to reference Lavie P, Scherson A: Ultrashort sleep-waking schedule. I. Evidence of ultradian rhythmicity in 'sleepability'. Electroencephalogr Clin Neurophysiol. 1981, 52: 163-74. 10.1016/0013-4694(81)90164-4.CrossRefPubMed Lavie P, Scherson A: Ultrashort sleep-waking schedule. I. Evidence of ultradian rhythmicity in 'sleepability'. Electroencephalogr Clin Neurophysiol. 1981, 52: 163-74. 10.1016/0013-4694(81)90164-4.CrossRefPubMed
25.
go back to reference Radloff LS: The CES-D scale : A self-report depression scale for research in the general population. Appl Psychol Measure. 1977, 1: 385-401. 10.1177/014662167700100306.CrossRef Radloff LS: The CES-D scale : A self-report depression scale for research in the general population. Appl Psychol Measure. 1977, 1: 385-401. 10.1177/014662167700100306.CrossRef
26.
go back to reference Spielberger CD, Gorsuch RL, Lushene R, Vagg PR, Jacobs GA: Manual for the State-Trait Anxiety Inventory. 1983, Palo Alto : Consulting Psychologists Press Spielberger CD, Gorsuch RL, Lushene R, Vagg PR, Jacobs GA: Manual for the State-Trait Anxiety Inventory. 1983, Palo Alto : Consulting Psychologists Press
27.
go back to reference Cohen J: Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: Lawrence Erlbaum, 2 Cohen J: Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: Lawrence Erlbaum, 2
28.
go back to reference Petruzzello SJ, Landers DM, Hatfield BD, Kubitz KA, Salazar W: A meta-analysis on the anxiety-reducing effects of acute and chronic exercise. Outcomes and mechanisms. Sports Med. 1991, 11 (3): 142-182.CrossRef Petruzzello SJ, Landers DM, Hatfield BD, Kubitz KA, Salazar W: A meta-analysis on the anxiety-reducing effects of acute and chronic exercise. Outcomes and mechanisms. Sports Med. 1991, 11 (3): 142-182.CrossRef
29.
go back to reference Lehrer PM, Carr R, Sargunaraj D, Woolfolk RL: Stress management techniques: are they all equivalent, or do they have specific effects?. Biofeedback Self Regul. 1994, 19 (4): 353-401. 10.1007/BF01776735.CrossRefPubMed Lehrer PM, Carr R, Sargunaraj D, Woolfolk RL: Stress management techniques: are they all equivalent, or do they have specific effects?. Biofeedback Self Regul. 1994, 19 (4): 353-401. 10.1007/BF01776735.CrossRefPubMed
30.
go back to reference Goel N, Etwaroo GR: Bright light, negative air ions and auditory stimuli produce rapid mood changes in a student population: a placebo-controlled study. Psychol Med. 2006, 36: 1253-63. 10.1017/S0033291706008002.CrossRefPubMed Goel N, Etwaroo GR: Bright light, negative air ions and auditory stimuli produce rapid mood changes in a student population: a placebo-controlled study. Psychol Med. 2006, 36: 1253-63. 10.1017/S0033291706008002.CrossRefPubMed
Metadata
Title
Does bright light have an anxiolytic effect? - an open trial
Authors
Shawn D Youngstedt
Daniel F Kripke
Publication date
01-12-2007
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2007
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-7-62

Other articles of this Issue 1/2007

BMC Psychiatry 1/2007 Go to the issue