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Journal of Assisted Reproduction and Genetics

Published in:

01-01-2006 | Original Paper

Does addition of low-dose aspirin and/or steroid as a standard treatment in nonselected intracytoplasmic sperm injection cycles improve in vitro fertilization success? A randomized, prospective, placebo-controlled study

Authors: Candan Iltemir Duvan, Batuhan Ozmen, Hakan Satıroglu, Cem Somer Atabekoglu, Bulent Berker

Published in: Journal of Assisted Reproduction and Genetics | Issue 1/2006

Abstract

Purpose: To investigate the effects of short-term low-dose aspirin and/or steroid use on implantation and pregnancy rates in nonselected intracytoplasmic sperm injection (ICSI) cycles.

Methods: Two-hundred patients undergoing ICSI for their first cycle were enrolled in this study. Participants were then randomized into four groups on the embryo transfer day. Aspirin (100 mg/day) in group A, prednisolone (10 mg/day) in group B, aspirin along with prednisolone in group C were given while placebo was administrated to group D.

Result: There were no statistically significant differences recorded in the demographic, ovulation induction cycle characteristics between groups. Mean transferred embryo number and mean top quality embryo number were similar among study groups. There were no statistical differences in implantation and pregnancy rates between study groups.

Conclusion: Administration of low-dose aspirin and prednisolone alone or concomitant as a standard treatment have no positive effects on implantation and/or pregnancy rates.

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Title: Does addition of low-dose aspirin and/or steroid as a standard treatment in nonselected intracytoplasmic sperm injection cycles improve in vitro fertilization success? A randomized, prospective, placebo-controlled study
Authors: Candan Iltemir Duvan
Batuhan Ozmen
Hakan Satıroglu
Cem Somer Atabekoglu
Bulent Berker
Publication date: 01-01-2006
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 1/2006
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-005-9003-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Does addition of low-dose aspirin and/or steroid as a standard treatment in nonselected intracytoplasmic sperm injection cycles improve in vitro fertilization success? A randomized, prospective, placebo-controlled study

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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