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Critical Care
Published in: Critical Care 1/2016

Open Access 01-12-2016 | Editorial

Do we need new prokinetics to reduce enteral feeding intolerance during critical illness?

Author: Arthur Raymond Hubert van Zanten

Published in: Critical Care | Issue 1/2016

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Abstract

Gastrointestinal feeding intolerance and critical illness-associated gastric motility dysfunction are common. Although recent guidelines recommend not interrupting gastric feeding when gastric residual volume (GRV) is lower than 500 mL or to completely abandon measurement of GRV, it may seem that the relevance of prokinetics is reduced.
In patients at risk for aspiration and in multimodal strategies to enhance feeding performance, however, use of prokinetics is still advocated. Metoclopramide and erythromycin are commonly used promotility agents, although with relevant side effects.
Potential targets for new agents and early study results are addressed.
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Metadata
Title
Do we need new prokinetics to reduce enteral feeding intolerance during critical illness?
Author
Arthur Raymond Hubert van Zanten
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2016
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-016-1466-3

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