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01-06-2020 | Original Paper

Diurnal variation of anterior segment parameters handled with Scheimpflug imaging in keratoconus patients

Authors: Ayşe Çiçek, Atılım Armağan Demirtaş, Cemal Özsaygılı, Zeynep Duru, Döndü Melek Ulusoy, Necati Duru, Mahmut Erkam Arslan, Hayrettin Çobanoğlu

Published in: International Ophthalmology | Issue 6/2020

Abstract

Purpose

To define diurnal changes in anterior segment parameters of keratoconus patients by using Scheimpflug imaging.

Methods

All keratoconus patients had corneal topography measurements 3 times a day (around 09:00 AM, 13:00 PM and 17:00 PM) by the same experienced operator. Three consecutive scans in each measurement session were obtained. The average of three measurements was used for analysis. A repeated measures analysis of variance with one within-subject factor (time of day) was carried out to assess diurnal variation.

Results

This study included 26 eyes of 26 patients with keratoconus. Significant diurnal variation was found in CCT and TCT measurements (P < 0.01, and P < 0.01, respectively). The mean amplitudes of change in CCT and TCT were 4.2 ± 1 µm (95% CI: 1.7–6.8 µm) and 4.1 ± 1.1 µm (95% CI: 1.2–8.0 µm), while the mean of CCT and TCT were 462.4 ± 34.5 µm (95% CI: 448.4–476.6 µm) and 452.9 ± 6.6 µm (95% CI: 439.3–466.5 µm), respectively. The maximum value and the lowest value were observed at 09:00 AM and at 17:00 PM, respectively. Other parameters except CCT and TCT did not show diurnal variation.

Conclusion

Statistically significant but clinically insignificant diurnal variation in CCT and TCT measurements of the keratoconus patients were detected over an 8-hour period (09:00 AM–17:00 PM).

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Title: Diurnal variation of anterior segment parameters handled with Scheimpflug imaging in keratoconus patients
Authors: Ayşe Çiçek
Atılım Armağan Demirtaş
Cemal Özsaygılı
Zeynep Duru
Döndü Melek Ulusoy
Necati Duru
Mahmut Erkam Arslan
Hayrettin Çobanoğlu
Publication date: 01-06-2020
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 6/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-020-01315-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diurnal variation of anterior segment parameters handled with Scheimpflug imaging in keratoconus patients

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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