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Published in: Journal of Medical Case Reports 1/2010

Open Access 01-12-2010 | Case report

Disseminated tuberculosis presenting with polymorphonuclear effusion and septic shock in an HIV-seropositive patient: a case report

Authors: Olivier Nancoz, Omar Kherad, Etienne Perrin, Christophe Hsu, Johannes Alexander Lobrinus, Mathieu Nendaz

Published in: Journal of Medical Case Reports | Issue 1/2010

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Abstract

Introduction

Because a substantial number of patients present with few or atypical symptoms, the recognition of tuberculosis remains challenging. Disseminated tuberculosis presenting with septic shock has already been described in some case reports, but, to the best of our knowledge, it has never been associated with polymorphonuclear effusion.

Case presentation

We describe the case of a 27-year-old man from western Africa who was seropositive for human immunodeficiency virus. He presented with pleural and abdominal polymorphonuclear effusions and quickly developed septic shock due to disseminated Mycobacterium tuberculosis infection leading to multiple organ failure and death.

Conclusion

In high-risk patients, Mycobacterium tuberculosis infection should be considered even in exceptional clinical presentations, such as septic shock and polymorphonuclear effusions.
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Literature
1.
go back to reference Kherad O, Herrmann F, Rochat T, Janssens JP: Tuberculosis in Geneva: a 4-year retrospective study. European Respiratory Society Annual Congress: Stockholm. 2007 Kherad O, Herrmann F, Rochat T, Janssens JP: Tuberculosis in Geneva: a 4-year retrospective study. European Respiratory Society Annual Congress: Stockholm. 2007
2.
go back to reference Clark TM, Burman WJ, Cohn DL, Mehler PS: Septic shock from mycobacterium tuberculosis after therapy for pneumocystis carinii. Arch Intern Med. 1998, 158: 1033-1035. 10.1001/archinte.158.9.1033.CrossRefPubMed Clark TM, Burman WJ, Cohn DL, Mehler PS: Septic shock from mycobacterium tuberculosis after therapy for pneumocystis carinii. Arch Intern Med. 1998, 158: 1033-1035. 10.1001/archinte.158.9.1033.CrossRefPubMed
3.
go back to reference Gachot B, Wolff M, Clair B, Regnier B: Severe tuberculosis in patient with immunodeficiency virus infection. Intensive Care Med. 1990, 16: 491-493. 10.1007/BF01709398.CrossRefPubMed Gachot B, Wolff M, Clair B, Regnier B: Severe tuberculosis in patient with immunodeficiency virus infection. Intensive Care Med. 1990, 16: 491-493. 10.1007/BF01709398.CrossRefPubMed
4.
go back to reference Vadillo M, Corbella X, Carratala J: AIDS presenting as septic shock caused by Mycobacterium tuberculosis. Scand J Infect Dis. 1994, 26: 105-106. 10.3109/00365549409008598.CrossRefPubMed Vadillo M, Corbella X, Carratala J: AIDS presenting as septic shock caused by Mycobacterium tuberculosis. Scand J Infect Dis. 1994, 26: 105-106. 10.3109/00365549409008598.CrossRefPubMed
5.
go back to reference Grigoriu BD, Jacobs FM, Mas AE, Prat D, Prévot S, Brivet FG: Disseminated tuberculosis with severe multi-organ failure in a patient with AIDS. Rev Mal Respir. 2008, 25 (7): 853-856.CrossRefPubMed Grigoriu BD, Jacobs FM, Mas AE, Prat D, Prévot S, Brivet FG: Disseminated tuberculosis with severe multi-organ failure in a patient with AIDS. Rev Mal Respir. 2008, 25 (7): 853-856.CrossRefPubMed
6.
go back to reference Chiu YS, Wang JT, Chang SC, Tang JL, Ku SC, Hung CC, Hsueh PR, Chen YC: Mycobacterium tuberculosis bacteremia in HIV-negative patients. J Formos Med Assoc. 2007, 106: 355-364. 10.1016/S0929-6646(09)60320-X.CrossRefPubMed Chiu YS, Wang JT, Chang SC, Tang JL, Ku SC, Hung CC, Hsueh PR, Chen YC: Mycobacterium tuberculosis bacteremia in HIV-negative patients. J Formos Med Assoc. 2007, 106: 355-364. 10.1016/S0929-6646(09)60320-X.CrossRefPubMed
7.
go back to reference Runo JR, Welch DC, Ness EM, Robbins IM, Milstone AP: Miliary tuberculosis as cause of acute empyema. Respiration. 2003, 70: 529-532. 10.1159/000074213.CrossRefPubMed Runo JR, Welch DC, Ness EM, Robbins IM, Milstone AP: Miliary tuberculosis as cause of acute empyema. Respiration. 2003, 70: 529-532. 10.1159/000074213.CrossRefPubMed
8.
go back to reference Michel P, Barbier C, Loubière Y, Hayon JH, Ricôme JL: Three cases of septic shock due to tuberculosis without HIV pathology. Intensive Care Med. 2002, 28: 1827-1828. 10.1007/s00134-002-1526-9.CrossRefPubMed Michel P, Barbier C, Loubière Y, Hayon JH, Ricôme JL: Three cases of septic shock due to tuberculosis without HIV pathology. Intensive Care Med. 2002, 28: 1827-1828. 10.1007/s00134-002-1526-9.CrossRefPubMed
9.
go back to reference Angoulvant D, Mohammedi I, Duperret S, Bouletreau P: Septic shock caused by Mycobacterium tuberculosis in a non-HIV patient. Intensive Care Med. 1999, 25: 238-10.1007/s001340050825.CrossRefPubMed Angoulvant D, Mohammedi I, Duperret S, Bouletreau P: Septic shock caused by Mycobacterium tuberculosis in a non-HIV patient. Intensive Care Med. 1999, 25: 238-10.1007/s001340050825.CrossRefPubMed
10.
go back to reference Sleisenger & Fordtran's gastrointestinal and liver disease. Pathophysiology Diagnosis Management. Edited by: Feldman M, Scharschmidt BF, Sleisenger MH. 2002, WB Saunders Company, 1522- Sleisenger & Fordtran's gastrointestinal and liver disease. Pathophysiology Diagnosis Management. Edited by: Feldman M, Scharschmidt BF, Sleisenger MH. 2002, WB Saunders Company, 1522-
11.
go back to reference Pérez-Rodriguez E, Jiménez Castro D, Light RW: Effusions from tuberculosis. Textbook of Pleural Diseases. Edited by: Light RW, Lee YCG. 2003, London: Arnold Press Pérez-Rodriguez E, Jiménez Castro D, Light RW: Effusions from tuberculosis. Textbook of Pleural Diseases. Edited by: Light RW, Lee YCG. 2003, London: Arnold Press
12.
13.
go back to reference Levine H, Szanto PB, Cugell DW: Tuberculous pleurisy: an acute illness. Arch Intern Med. 1968, 122: 329-332. 10.1001/archinte.122.4.329.CrossRefPubMed Levine H, Szanto PB, Cugell DW: Tuberculous pleurisy: an acute illness. Arch Intern Med. 1968, 122: 329-332. 10.1001/archinte.122.4.329.CrossRefPubMed
14.
go back to reference Gopi A, Madhavan SM, Sharma SK, Sahn SA: Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest. 2007, 131: 880-889. 10.1378/chest.06-2063.CrossRefPubMed Gopi A, Madhavan SM, Sharma SK, Sahn SA: Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest. 2007, 131: 880-889. 10.1378/chest.06-2063.CrossRefPubMed
15.
go back to reference Trajman A, Pai M, Dheda K, van Zyl Smit R, Zwerling AA, Joshi R, Kalantri S, Daley P, Menzies D: Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?. Eur Respir J. 2008, 31: 1098-1106. 10.1183/09031936.00147507.CrossRefPubMed Trajman A, Pai M, Dheda K, van Zyl Smit R, Zwerling AA, Joshi R, Kalantri S, Daley P, Menzies D: Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?. Eur Respir J. 2008, 31: 1098-1106. 10.1183/09031936.00147507.CrossRefPubMed
Metadata
Title
Disseminated tuberculosis presenting with polymorphonuclear effusion and septic shock in an HIV-seropositive patient: a case report
Authors
Olivier Nancoz
Omar Kherad
Etienne Perrin
Christophe Hsu
Johannes Alexander Lobrinus
Mathieu Nendaz
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-4-155

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