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Clinical Sarcoma Research
Published in: Clinical Sarcoma Research 1/2017

Open Access 01-12-2017 | Case Report

Disseminated and late metastatic disease from nasal pit leiomyosarcoma after radical surgical resection. Case report of a singular presentation of a rare disease

Authors: Enrico Pinotti, Marta Sandini, Simone Famularo, Marta Jaconi, Fabrizio Romano, Luca Nespoli, Luca Gianotti

Published in: Clinical Sarcoma Research | Issue 1/2017

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Abstract

Background

Leiomyosarcoma of the head and neck is a rare cancer with high local aggressiveness. Radical surgery and adjuvant treatment offer the best chance for cure, nonetheless 5-years recurrence rate remains high. Despite international guidelines are available for soft tissue sarcomas, no recommendations are specifically endorsed for leiomyosarcoma of the head and neck, due to the rarity of its presentation and consequently scarcity of data on long-term outcome.

Case presentation

A 50-year old woman, operated 10 years before for leiomyosarcoma of the nasal pit and with negative 5-years follow-up, was admitted to our ward for impairment of the hepatic function. Total-body CT scan detected multiple localizations at lungs, kidneys, pancreas, bones, muscles, lymph nodes and thyroid. The pathologic report after lung biopsy confirmed the diagnosis of metastasis from leiomyosarcoma and the patients was scheduled for first line chemo-radiotherapy.

Conclusions

Despite adequate primary treatment, distant and disseminated metastatic disease may be not excluded in leiomyosarcoma of the head and neck.
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Metadata
Title
Disseminated and late metastatic disease from nasal pit leiomyosarcoma after radical surgical resection. Case report of a singular presentation of a rare disease
Authors
Enrico Pinotti
Marta Sandini
Simone Famularo
Marta Jaconi
Fabrizio Romano
Luca Nespoli
Luca Gianotti
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Clinical Sarcoma Research / Issue 1/2017
Electronic ISSN: 2045-3329
DOI
https://doi.org/10.1186/s13569-017-0078-2

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