Skip to main content
Top
Published in: Neurosurgical Review 2/2007

01-04-2007 | Review

Direct cerebral oxygenation monitoring—a systematic review of recent publications

Authors: Erhard W. Lang, Jamin M. Mulvey, Yugan Mudaliar, Nicholas W. C. Dorsch

Published in: Neurosurgical Review | Issue 2/2007

Login to get access

Abstract

This review has been compiled to assess publications related to the clinical application of direct cerebral tissue oxygenation (PtiO2) monitoring published in international, peer-reviewed scientific journals. Its goal was to extract relevant, i.e. positive and negative information on indications, clinical application, safety issues and impact on clinical situations as well as treatment strategies in neurosurgery, neurosurgical anaesthesiology, neurosurgical intensive care, neurology and related specialties. For completeness’ sake it also presents some related basic science research. PtiO2 monitoring technology is a safe and valuable cerebral monitoring device in neurocritical care. Although a randomized outcome study is not available its clinical utility has repeatedly been clearly confirmed because it adds a monitoring parameter, independent from established cerebral monitoring devices. It offers new insights into cerebral physiology and pathophysiology. Pathologic values have been established in peer-reviewed research, which are not only relevant to outcome but are treatable. The benefits clearly outweigh the risks, which remains unchallenged in all publications retrieved. It is particularly attractive because it offers continuous, real-time data and is available at the bedside.
Literature
1.
go back to reference Albano C, Comandante L, Nolan S (2005) Innovations in the management of cerebral injury. Crit Care Nurs Q 28:135–149PubMed Albano C, Comandante L, Nolan S (2005) Innovations in the management of cerebral injury. Crit Care Nurs Q 28:135–149PubMed
2.
go back to reference Alessandri B, Hoelper BM, Behr R, Kempski O (2004) Accuracy and stability of temperature probes for intracranial application. J Neurosci Methods 139:161–165PubMedCrossRef Alessandri B, Hoelper BM, Behr R, Kempski O (2004) Accuracy and stability of temperature probes for intracranial application. J Neurosci Methods 139:161–165PubMedCrossRef
3.
go back to reference Baumgartl H, Lubbers DW (1983) Microaxial needle sensors for polarographic measurements of local O2 in the cellular range of living tissue. In: Gnaiger E, Foerstner H (eds) Polarographic oxygen sensors. Springer, Berlin Heidelberg New York, pp 37–65 Baumgartl H, Lubbers DW (1983) Microaxial needle sensors for polarographic measurements of local O2 in the cellular range of living tissue. In: Gnaiger E, Foerstner H (eds) Polarographic oxygen sensors. Springer, Berlin Heidelberg New York, pp 37–65
4.
go back to reference Becker A, Kuhnt T, Liedtke H, Krivokuca A, Bloching M, Dunst J (2002) Oxygenation measurements in head and neck cancers during hyperbaric oxygenation. Strahlenther Onkol 178:105–108PubMedCrossRef Becker A, Kuhnt T, Liedtke H, Krivokuca A, Bloching M, Dunst J (2002) Oxygenation measurements in head and neck cancers during hyperbaric oxygenation. Strahlenther Onkol 178:105–108PubMedCrossRef
5.
go back to reference Belda FJ, Aguilar G, Soro M, Maruenda A (2004) Ventilatory management of the severely brain-injured patient (in Spanish). Rev Esp Anestesiol Reanim 51:143–150PubMed Belda FJ, Aguilar G, Soro M, Maruenda A (2004) Ventilatory management of the severely brain-injured patient (in Spanish). Rev Esp Anestesiol Reanim 51:143–150PubMed
6.
go back to reference Brawanski A, Faltermeier R, Rothoerl RD, Woertgen C (2002) Comparison of near-infrared spectroscopy and tissue p(O2) time series in patients after severe head injury and aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab 22:605–611PubMedCrossRef Brawanski A, Faltermeier R, Rothoerl RD, Woertgen C (2002) Comparison of near-infrared spectroscopy and tissue p(O2) time series in patients after severe head injury and aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab 22:605–611PubMedCrossRef
7.
go back to reference Burger R, Bendszus M, Vince GH, Roosen K, Marmarou A (2002) A new reproducible model of an epidural mass lesion in rodents. Part I: characterization by neurophysiological monitoring, magnetic resonance imaging, and histopathological analysis. J Neurosurg 97:1410–1418PubMed Burger R, Bendszus M, Vince GH, Roosen K, Marmarou A (2002) A new reproducible model of an epidural mass lesion in rodents. Part I: characterization by neurophysiological monitoring, magnetic resonance imaging, and histopathological analysis. J Neurosurg 97:1410–1418PubMed
8.
go back to reference Carre E, Cantais E, Darbin O, Terrier JP, Lonjon M, Palmier B, Risso JJ (2004) Technical aspects of an impact acceleration traumatic brain injury rat model with potential suitability for both microdialysis and PtiO2 monitoring. J Neurosci Methods 140:23–28PubMedCrossRef Carre E, Cantais E, Darbin O, Terrier JP, Lonjon M, Palmier B, Risso JJ (2004) Technical aspects of an impact acceleration traumatic brain injury rat model with potential suitability for both microdialysis and PtiO2 monitoring. J Neurosci Methods 140:23–28PubMedCrossRef
9.
go back to reference Carvi y Nievas M, Toktamis S, Hollerhage HG, Haas E (2005) Hyperacute measurement of brain-tissue oxygen, carbon dioxide, pH, and intracranial pressure before, during, and after cerebral angiography in patients with aneurysmatic subarachnoid hemorrhage in poor condition. Surg Neurol 64:362–367; discussion 367PubMedCrossRef Carvi y Nievas M, Toktamis S, Hollerhage HG, Haas E (2005) Hyperacute measurement of brain-tissue oxygen, carbon dioxide, pH, and intracranial pressure before, during, and after cerebral angiography in patients with aneurysmatic subarachnoid hemorrhage in poor condition. Surg Neurol 64:362–367; discussion 367PubMedCrossRef
10.
go back to reference Cavus E, Dorges V, Wagner-Berger H, Stadlbauer KH, Steinfath M, Wenzel V, Bein B, Scholz J (2005) Changes of local brain tissue oxygen pressure after vasopressin during spontaneous circulation. Acta Neurochir (Wien) 147:283–290; discussion 290CrossRef Cavus E, Dorges V, Wagner-Berger H, Stadlbauer KH, Steinfath M, Wenzel V, Bein B, Scholz J (2005) Changes of local brain tissue oxygen pressure after vasopressin during spontaneous circulation. Acta Neurochir (Wien) 147:283–290; discussion 290CrossRef
11.
go back to reference Clausen T, Khaldi A, Zauner A, Reinert M, Doppenberg E, Menzel M, Soukup J, Alves OL, Bullock MR (2005) Cerebral acid-base homeostasis after severe traumatic brain injury. J Neurosurg 103:597–607PubMed Clausen T, Khaldi A, Zauner A, Reinert M, Doppenberg E, Menzel M, Soukup J, Alves OL, Bullock MR (2005) Cerebral acid-base homeostasis after severe traumatic brain injury. J Neurosurg 103:597–607PubMed
12.
go back to reference Clausen T, Scharf A, Menzel M, Soukup J, Holz C, Rieger A, Hanisch F, Brath E, Nemeth N, Miko I, Vajkoczy P, Radke J, Henze D (2004) Influence of moderate and profound hyperventilation on cerebral blood flow, oxygenation and metabolism. Brain Res 1019:113–123PubMedCrossRef Clausen T, Scharf A, Menzel M, Soukup J, Holz C, Rieger A, Hanisch F, Brath E, Nemeth N, Miko I, Vajkoczy P, Radke J, Henze D (2004) Influence of moderate and profound hyperventilation on cerebral blood flow, oxygenation and metabolism. Brain Res 1019:113–123PubMedCrossRef
13.
go back to reference Dings J, Jager A, Meixensberger J, Roosen K (1998) Brain tissue pO2 and outcome after severe head injury. Neurol Res 20(Suppl 1):S71–S75PubMed Dings J, Jager A, Meixensberger J, Roosen K (1998) Brain tissue pO2 and outcome after severe head injury. Neurol Res 20(Suppl 1):S71–S75PubMed
14.
go back to reference Dings J, Meixensberger J, Amschler J, Hamelbeck B, Roosen K (1996) Brain tissue pO2 in relation to cerebral perfusion pressure, TCD findings and TCD-CO2-reactivity after severe head injury. Acta Neurochir (Wien) 138:425–434CrossRef Dings J, Meixensberger J, Amschler J, Hamelbeck B, Roosen K (1996) Brain tissue pO2 in relation to cerebral perfusion pressure, TCD findings and TCD-CO2-reactivity after severe head injury. Acta Neurochir (Wien) 138:425–434CrossRef
15.
go back to reference Dings J, Meixensberger J, Amschler J, Roosen K (1996) Continuous monitoring of brain tissue PO2: a new tool to minimize the risk of ischemia caused by hyperventilation therapy. Zentralbl Neurochir 57:177–183PubMed Dings J, Meixensberger J, Amschler J, Roosen K (1996) Continuous monitoring of brain tissue PO2: a new tool to minimize the risk of ischemia caused by hyperventilation therapy. Zentralbl Neurochir 57:177–183PubMed
16.
go back to reference Dings J, Meixensberger J, Jager A, Roosen K (1998) Clinical experience with 118 brain tissue oxygen partial pressure catheter probes. Neurosurgery 43:1082–1095PubMedCrossRef Dings J, Meixensberger J, Jager A, Roosen K (1998) Clinical experience with 118 brain tissue oxygen partial pressure catheter probes. Neurosurgery 43:1082–1095PubMedCrossRef
17.
go back to reference Dings J, Meixensberger J, Roosen K (1997) Brain tissue pO2-monitoring: catheter stability and complications. Neurol Res 19:241–245PubMed Dings J, Meixensberger J, Roosen K (1997) Brain tissue pO2-monitoring: catheter stability and complications. Neurol Res 19:241–245PubMed
18.
go back to reference Gelabert-Gonzalez M, Fernandez-Villa JM, Ginesta-Galan V (2002) Intra-operative monitoring of brain tissue O2 (PtiO2) during aneurysm surgery. Acta Neurochir (Wien) 144:863–866; discussion 866–867CrossRef Gelabert-Gonzalez M, Fernandez-Villa JM, Ginesta-Galan V (2002) Intra-operative monitoring of brain tissue O2 (PtiO2) during aneurysm surgery. Acta Neurochir (Wien) 144:863–866; discussion 866–867CrossRef
19.
go back to reference Gonzalez H, Hunter CJ, Bennet L, Power GG, Gunn AJ (2005) Cerebral oxygenation during postasphyxial seizures in near-term fetal sheep. J Cereb Blood Flow Metab 25:911–918PubMedCrossRef Gonzalez H, Hunter CJ, Bennet L, Power GG, Gunn AJ (2005) Cerebral oxygenation during postasphyxial seizures in near-term fetal sheep. J Cereb Blood Flow Metab 25:911–918PubMedCrossRef
20.
go back to reference Gracias VH, Guillamondegui OD, Stiefel MF, Wilensky EM, Bloom S, Gupta R, Pryor JP, Reilly PM, Leroux PD, Schwab CW (2004) Cerebral cortical oxygenation: a pilot study. J Trauma 56:469–472; discussion 464–472PubMed Gracias VH, Guillamondegui OD, Stiefel MF, Wilensky EM, Bloom S, Gupta R, Pryor JP, Reilly PM, Leroux PD, Schwab CW (2004) Cerebral cortical oxygenation: a pilot study. J Trauma 56:469–472; discussion 464–472PubMed
21.
go back to reference Hare GM, Hum KM, Kim SY, Barr A, Baker AJ, Mazer CD (2004) Increased cerebral tissue oxygen tension after extensive hemodilution with a hemoglobin-based oxygen carrier. Anesth Analg 99:528–535, table of contentsPubMedCrossRef Hare GM, Hum KM, Kim SY, Barr A, Baker AJ, Mazer CD (2004) Increased cerebral tissue oxygen tension after extensive hemodilution with a hemoglobin-based oxygen carrier. Anesth Analg 99:528–535, table of contentsPubMedCrossRef
22.
go back to reference Hartl R, Bardt TF, Kiening KL, Sarrafzadeh AS, Schneider GH, Unterberg AW (1997) Mannitol decreases ICP but does not improve brain-tissue pO2 in severely head-injured patients with intracranial hypertension. Acta Neurochir Suppl 70:40–42PubMed Hartl R, Bardt TF, Kiening KL, Sarrafzadeh AS, Schneider GH, Unterberg AW (1997) Mannitol decreases ICP but does not improve brain-tissue pO2 in severely head-injured patients with intracranial hypertension. Acta Neurochir Suppl 70:40–42PubMed
23.
go back to reference Hemphill JC 3rd, Morabito D, Farrant M, Manley GT (2005) Brain tissue oxygen monitoring in intracerebral hemorrhage. Neurocrit Care 3:260–270PubMedCrossRef Hemphill JC 3rd, Morabito D, Farrant M, Manley GT (2005) Brain tissue oxygen monitoring in intracerebral hemorrhage. Neurocrit Care 3:260–270PubMedCrossRef
24.
go back to reference Hlatky R, Valadka AB, Robertson CS (2005) Intracranial pressure response to induced hypertension: role of dynamic pressure autoregulation. Neurosurgery 57:917–923; discussion 917–923PubMedCrossRef Hlatky R, Valadka AB, Robertson CS (2005) Intracranial pressure response to induced hypertension: role of dynamic pressure autoregulation. Neurosurgery 57:917–923; discussion 917–923PubMedCrossRef
25.
go back to reference Hoelper BM, Alessandri B, Heimann A, Behr R, Kempski O (2005) Brain oxygen monitoring: in-vitro accuracy, long-term drift and response-time of Licox- and Neurotrend sensors. Acta Neurochir (Wien) 147:767–774CrossRef Hoelper BM, Alessandri B, Heimann A, Behr R, Kempski O (2005) Brain oxygen monitoring: in-vitro accuracy, long-term drift and response-time of Licox- and Neurotrend sensors. Acta Neurochir (Wien) 147:767–774CrossRef
26.
go back to reference Ibanez J, Vilalta A, Mena MP, Vilalta J, Topczewski T, Noguer M, Sahuquillo J, Rubio E (2003) Intraoperative detection of ischemic brain hypoxia using oxygen tissue pressure microprobes (in Spanish). Neurocirugia (Astur) 14:483–489; discussion 490 Ibanez J, Vilalta A, Mena MP, Vilalta J, Topczewski T, Noguer M, Sahuquillo J, Rubio E (2003) Intraoperative detection of ischemic brain hypoxia using oxygen tissue pressure microprobes (in Spanish). Neurocirugia (Astur) 14:483–489; discussion 490
27.
go back to reference Imberti R, Bellinzona G, Riccardi F, Pagani M, Langer M (2003) Cerebral perfusion pressure and cerebral tissue oxygen tension in a patient during cardiopulmonary resuscitation. Intensive Care Med 29:1016–1019PubMed Imberti R, Bellinzona G, Riccardi F, Pagani M, Langer M (2003) Cerebral perfusion pressure and cerebral tissue oxygen tension in a patient during cardiopulmonary resuscitation. Intensive Care Med 29:1016–1019PubMed
28.
go back to reference Jaeger M, Schuhmann MU, Soehle M, Meixensberger J (2006) Continuous assessment of cerebrovascular autoregulation after traumatic brain injury using brain tissue oxygen pressure reactivity. Crit Care Med 34:1783–1788PubMedCrossRef Jaeger M, Schuhmann MU, Soehle M, Meixensberger J (2006) Continuous assessment of cerebrovascular autoregulation after traumatic brain injury using brain tissue oxygen pressure reactivity. Crit Care Med 34:1783–1788PubMedCrossRef
29.
go back to reference Jaeger M, Soehle M, Meixensberger J (2003) Effects of decompressive craniectomy on brain tissue oxygen in patients with intracranial hypertension. J Neurol Neurosurg Psychiatry 74:513–515PubMedCrossRef Jaeger M, Soehle M, Meixensberger J (2003) Effects of decompressive craniectomy on brain tissue oxygen in patients with intracranial hypertension. J Neurol Neurosurg Psychiatry 74:513–515PubMedCrossRef
30.
go back to reference Jaeger M, Soehle M, Meixensberger J (2005) Brain tissue oxygen (PtiO2): a clinical comparison of two monitoring devices. Acta Neurochir Suppl 95:79–81PubMedCrossRef Jaeger M, Soehle M, Meixensberger J (2005) Brain tissue oxygen (PtiO2): a clinical comparison of two monitoring devices. Acta Neurochir Suppl 95:79–81PubMedCrossRef
31.
go back to reference Jaeger M, Soehle M, Schuhmann MU, Winkler D, Meixensberger J (2005) Correlation of continuously monitored regional cerebral blood flow and brain tissue oxygen. Acta Neurochir (Wien) 147:51–56; discussion 56CrossRef Jaeger M, Soehle M, Schuhmann MU, Winkler D, Meixensberger J (2005) Correlation of continuously monitored regional cerebral blood flow and brain tissue oxygen. Acta Neurochir (Wien) 147:51–56; discussion 56CrossRef
32.
go back to reference Jia J, Lin YQ, Liu WF, Zhong TA, Zhang J, Ye Y, Xu YQ (2005) Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury. Chin J Traumatol 8:138–141PubMed Jia J, Lin YQ, Liu WF, Zhong TA, Zhang J, Ye Y, Xu YQ (2005) Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury. Chin J Traumatol 8:138–141PubMed
33.
go back to reference Jodicke A, Hubner F, Boker DK (2003) Monitoring of brain tissue oxygenation during aneurysm surgery: prediction of procedure-related ischemic events. J Neurosurg 98:515–523PubMed Jodicke A, Hubner F, Boker DK (2003) Monitoring of brain tissue oxygenation during aneurysm surgery: prediction of procedure-related ischemic events. J Neurosurg 98:515–523PubMed
34.
go back to reference Johnston AJ, Steiner LA, Chatfield DA, Coleman MR, Coles JP, Al-Rawi PG, Menon DK, Gupta AK (2003) Effects of propofol on cerebral oxygenation and metabolism after head injury. Br J Anaesth 91:781–786PubMedCrossRef Johnston AJ, Steiner LA, Chatfield DA, Coleman MR, Coles JP, Al-Rawi PG, Menon DK, Gupta AK (2003) Effects of propofol on cerebral oxygenation and metabolism after head injury. Br J Anaesth 91:781–786PubMedCrossRef
35.
go back to reference Johnston AJ, Steiner LA, Chatfield DA, Coles JP, Hutchinson PJ, Al-Rawi PG, Menon DK, Gupta AK (2004) Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury. Intensive Care Med 30:791–797PubMedCrossRef Johnston AJ, Steiner LA, Chatfield DA, Coles JP, Hutchinson PJ, Al-Rawi PG, Menon DK, Gupta AK (2004) Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury. Intensive Care Med 30:791–797PubMedCrossRef
36.
go back to reference Kett-White R, Hutchinson PJ, Al-Rawi PG, Gupta AK, Pickard JD, Kirkpatrick PJ (2002) Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes. Neurosurgery 50:1213–1221; discussion 1221–1212PubMedCrossRef Kett-White R, Hutchinson PJ, Al-Rawi PG, Gupta AK, Pickard JD, Kirkpatrick PJ (2002) Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes. Neurosurgery 50:1213–1221; discussion 1221–1212PubMedCrossRef
37.
go back to reference Kiening KL, Unterberg AW, Bardt TF, Schneider GH, Lanksch WR (1996) Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 85:751–757PubMedCrossRef Kiening KL, Unterberg AW, Bardt TF, Schneider GH, Lanksch WR (1996) Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 85:751–757PubMedCrossRef
38.
go back to reference Lang EW, Czosnyka M, Mehdorn HM (2003) Tissue oxygen reactivity and cerebral autoregulation after severe traumatic brain injury. Crit Care Med 31:267–271PubMedCrossRef Lang EW, Czosnyka M, Mehdorn HM (2003) Tissue oxygen reactivity and cerebral autoregulation after severe traumatic brain injury. Crit Care Med 31:267–271PubMedCrossRef
39.
go back to reference Lang EW, Lagopoulos J, Griffith J, Yip K, Yam A, Mudaliar Y, Mehdorn HM, Dorsch NW (2003) Cerebral vasomotor reactivity testing in head injury: the link between pressure and flow. J Neurol Neurosurg Psychiatry 74:1053–1059PubMedCrossRef Lang EW, Lagopoulos J, Griffith J, Yip K, Yam A, Mudaliar Y, Mehdorn HM, Dorsch NW (2003) Cerebral vasomotor reactivity testing in head injury: the link between pressure and flow. J Neurol Neurosurg Psychiatry 74:1053–1059PubMedCrossRef
40.
go back to reference Lubbers DW, Baumgartl H (1997) Heterogeneities and profiles of oxygen pressure in brain and kidney as examples of the pO2 distribution in the living tissue. Kidney Int 51:372–380PubMed Lubbers DW, Baumgartl H (1997) Heterogeneities and profiles of oxygen pressure in brain and kidney as examples of the pO2 distribution in the living tissue. Kidney Int 51:372–380PubMed
41.
go back to reference Maas AI, Fleckenstein W, de Jong DA, van Santbrink H (1993) Monitoring cerebral oxygenation: experimental studies and preliminary clinical results of continuous monitoring of cerebrospinal fluid and brain tissue oxygen tension. Acta Neurochir Suppl (Wien) 59:50–57 Maas AI, Fleckenstein W, de Jong DA, van Santbrink H (1993) Monitoring cerebral oxygenation: experimental studies and preliminary clinical results of continuous monitoring of cerebrospinal fluid and brain tissue oxygen tension. Acta Neurochir Suppl (Wien) 59:50–57
42.
go back to reference McLeod AD, Igielman F, Elwell C, Cope M, Smith M (2003) Measuring cerebral oxygenation during normobaric hyperoxia: a comparison of tissue microprobes, near-infrared spectroscopy, and jugular venous oximetry in head injury. Anesth Analg 97:851–856PubMedCrossRef McLeod AD, Igielman F, Elwell C, Cope M, Smith M (2003) Measuring cerebral oxygenation during normobaric hyperoxia: a comparison of tissue microprobes, near-infrared spectroscopy, and jugular venous oximetry in head injury. Anesth Analg 97:851–856PubMedCrossRef
43.
go back to reference Meixensberger J, Baunach S, Amschler J, Dings J, Roosen K (1997) Influence of body position on tissue-pO2, cerebral perfusion pressure and intracranial pressure in patients with acute brain injury. Neurol Res 19:249–253PubMed Meixensberger J, Baunach S, Amschler J, Dings J, Roosen K (1997) Influence of body position on tissue-pO2, cerebral perfusion pressure and intracranial pressure in patients with acute brain injury. Neurol Res 19:249–253PubMed
44.
go back to reference Meixensberger J, Jager A, Dings J, Baunach S, Roosen K (1998) Multimodal hemodynamic neuromonitoring-quality and consequences for therapy of severely head injured patients. Acta Neurochir Suppl 71:260–262PubMed Meixensberger J, Jager A, Dings J, Baunach S, Roosen K (1998) Multimodal hemodynamic neuromonitoring-quality and consequences for therapy of severely head injured patients. Acta Neurochir Suppl 71:260–262PubMed
45.
go back to reference Meixensberger J, Renner C, Simanowski R, Schmidtke A, Dings J, Roosen K (2004) Influence of cerebral oxygenation following severe head injury on neuropsychological testing. Neurol Res 26:414–417PubMedCrossRef Meixensberger J, Renner C, Simanowski R, Schmidtke A, Dings J, Roosen K (2004) Influence of cerebral oxygenation following severe head injury on neuropsychological testing. Neurol Res 26:414–417PubMedCrossRef
46.
go back to reference Mulvey JM, Dorsch NW, Mudaliar Y, Lang EW (2004) Multimodality monitoring in severe traumatic brain injury: the role of brain tissue oxygenation monitoring. Neurocrit Care 1:391–402PubMedCrossRef Mulvey JM, Dorsch NW, Mudaliar Y, Lang EW (2004) Multimodality monitoring in severe traumatic brain injury: the role of brain tissue oxygenation monitoring. Neurocrit Care 1:391–402PubMedCrossRef
47.
go back to reference Ng I, Lim J, Wong HB (2004) Effects of head posture on cerebral hemodynamics: its influences on intracranial pressure, cerebral perfusion pressure, and cerebral oxygenation. Neurosurgery 54:593–597; discussion 598PubMedCrossRef Ng I, Lim J, Wong HB (2004) Effects of head posture on cerebral hemodynamics: its influences on intracranial pressure, cerebral perfusion pressure, and cerebral oxygenation. Neurosurgery 54:593–597; discussion 598PubMedCrossRef
48.
go back to reference Okonkwo DO, Wagner J, Melon DE, Alden T, Stone JR, Helm GA, Jane JA Sr (2003) Trans-sodium crocetinate increases oxygen delivery to brain parenchyma in rats on oxygen supplementation. Neurosci Lett 352:97–100PubMedCrossRef Okonkwo DO, Wagner J, Melon DE, Alden T, Stone JR, Helm GA, Jane JA Sr (2003) Trans-sodium crocetinate increases oxygen delivery to brain parenchyma in rats on oxygen supplementation. Neurosci Lett 352:97–100PubMedCrossRef
49.
go back to reference Raabe A, Gottschalk A, Hommel M, Dubben HH, Strandl T (2005) No effect of the hemoglobin solution HBOC-201 on the response of the rat R1H tumor to fractionated irradiation. Strahlenther Onkol 181:730–737PubMedCrossRef Raabe A, Gottschalk A, Hommel M, Dubben HH, Strandl T (2005) No effect of the hemoglobin solution HBOC-201 on the response of the rat R1H tumor to fractionated irradiation. Strahlenther Onkol 181:730–737PubMedCrossRef
50.
go back to reference Reinert M, Barth A, Rothen HU, Schaller B, Takala J, Seiler RW (2003) Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury. Acta Neurochir (Wien) 145:341–349; discussion 349–350 Reinert M, Barth A, Rothen HU, Schaller B, Takala J, Seiler RW (2003) Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury. Acta Neurochir (Wien) 145:341–349; discussion 349–350
51.
go back to reference Reithmeier T, Lohr M, Pakos P, Ketter G, Ernestus RI (2005) Relevance of ICP and ptiO(2) for indication and timing of decompressive craniectomy in patients with malignant brain edema. Acta Neurochir (Wien) 147:947–952CrossRef Reithmeier T, Lohr M, Pakos P, Ketter G, Ernestus RI (2005) Relevance of ICP and ptiO(2) for indication and timing of decompressive craniectomy in patients with malignant brain edema. Acta Neurochir (Wien) 147:947–952CrossRef
52.
go back to reference Rossi S, Balestreri M, Spagnoli D, Bellinzona G, Valeriani V, Bruzzone P, Maestri M, Stocchetti N (2000) Oxygen delivery and oxygen tension in cerebral tissue during global cerebral ischaemia: a swine model. Acta Neurochir Suppl 76:199–202PubMed Rossi S, Balestreri M, Spagnoli D, Bellinzona G, Valeriani V, Bruzzone P, Maestri M, Stocchetti N (2000) Oxygen delivery and oxygen tension in cerebral tissue during global cerebral ischaemia: a swine model. Acta Neurochir Suppl 76:199–202PubMed
53.
go back to reference Rossi S, Stocchetti N, Longhi L, Balestreri M, Spagnoli D, Zanier ER, Bellinzona G (2001) Brain oxygen tension, oxygen supply, and oxygen consumption during arterial hyperoxia in a model of progressive cerebral ischemia. J Neurotrauma 18:163–174PubMedCrossRef Rossi S, Stocchetti N, Longhi L, Balestreri M, Spagnoli D, Zanier ER, Bellinzona G (2001) Brain oxygen tension, oxygen supply, and oxygen consumption during arterial hyperoxia in a model of progressive cerebral ischemia. J Neurotrauma 18:163–174PubMedCrossRef
54.
go back to reference Sarrafzadeh AS, Kiening KL, Bardt TF, Hartl R, Schneider GH, Unterberg AW (1997) Monitoring cerebral oxygenation: a methodological comparison (in German). Anasthesiol Intensivmed Notfallmed Schmerzther 32:S224–S230PubMed Sarrafzadeh AS, Kiening KL, Bardt TF, Hartl R, Schneider GH, Unterberg AW (1997) Monitoring cerebral oxygenation: a methodological comparison (in German). Anasthesiol Intensivmed Notfallmed Schmerzther 32:S224–S230PubMed
55.
go back to reference Sarrafzadeh AS, Kiening KL, Bardt TF, Schneider GH, Unterberg AW, Lanksch WR (1998) Cerebral oxygenation in contusioned vs. nonlesioned brain tissue: monitoring of PtiO2 with Licox and Paratrend. Acta Neurochir Suppl 71:186–189PubMed Sarrafzadeh AS, Kiening KL, Bardt TF, Schneider GH, Unterberg AW, Lanksch WR (1998) Cerebral oxygenation in contusioned vs. nonlesioned brain tissue: monitoring of PtiO2 with Licox and Paratrend. Acta Neurochir Suppl 71:186–189PubMed
56.
go back to reference Sarrafzadeh AS, Kiening KL, Callsen TA, Unterberg AW (2003) Metabolic changes during impending and manifest cerebral hypoxia in traumatic brain injury. Br J Neurosurg 17:340–346PubMedCrossRef Sarrafzadeh AS, Kiening KL, Callsen TA, Unterberg AW (2003) Metabolic changes during impending and manifest cerebral hypoxia in traumatic brain injury. Br J Neurosurg 17:340–346PubMedCrossRef
57.
go back to reference Sarrafzadeh AS, Kiening KL, Unterberg AW (2003) Neuromonitoring: brain oxygenation and microdialysis. Curr Neurol Neurosci Rep 3:517–523PubMed Sarrafzadeh AS, Kiening KL, Unterberg AW (2003) Neuromonitoring: brain oxygenation and microdialysis. Curr Neurol Neurosci Rep 3:517–523PubMed
58.
go back to reference Sarrafzadeh AS, Peltonen EE, Kaisers U, Kuchler I, Lanksch WR, Unterberg AW (2001) Secondary insults in severe head injury-do multiply injured patients do worse? Crit Care Med 29:1116–1123PubMedCrossRef Sarrafzadeh AS, Peltonen EE, Kaisers U, Kuchler I, Lanksch WR, Unterberg AW (2001) Secondary insults in severe head injury-do multiply injured patients do worse? Crit Care Med 29:1116–1123PubMedCrossRef
59.
go back to reference Sarrafzadeh AS, Sakowitz OW, Callsen TA, Lanksch WR, Unterberg AW (2002) Detection of secondary insults by brain tissue pO2 and bedside microdialysis in severe head injury. Acta Neurochir Suppl 81:319–321PubMed Sarrafzadeh AS, Sakowitz OW, Callsen TA, Lanksch WR, Unterberg AW (2002) Detection of secondary insults by brain tissue pO2 and bedside microdialysis in severe head injury. Acta Neurochir Suppl 81:319–321PubMed
60.
go back to reference Sarrafzadeh AS, Unterberg AW, Lanksch WR (1998) Bedside-microdialysis for early detection of vasospasm after subarachnoid hemorrhage. Case report and review of the literature. Zentralbl Neurochir 59:269–273PubMed Sarrafzadeh AS, Unterberg AW, Lanksch WR (1998) Bedside-microdialysis for early detection of vasospasm after subarachnoid hemorrhage. Case report and review of the literature. Zentralbl Neurochir 59:269–273PubMed
61.
go back to reference Scheufler KM, Lehnert A, Rohrborn HJ, Nadstawek J, Thees C (2004) Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion. J Neurosurg Anesthesiol 16:210–219PubMedCrossRef Scheufler KM, Lehnert A, Rohrborn HJ, Nadstawek J, Thees C (2004) Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion. J Neurosurg Anesthesiol 16:210–219PubMedCrossRef
62.
go back to reference Schneider GH, Sarrafzadeh AS, Kiening KL, Bardt TF, Unterberg AW, Lanksch WR (1998) Influence of hyperventilation on brain tissue-PO2, PCO2, and pH in patients with intracranial hypertension. Acta Neurochir Suppl 71:62–65PubMed Schneider GH, Sarrafzadeh AS, Kiening KL, Bardt TF, Unterberg AW, Lanksch WR (1998) Influence of hyperventilation on brain tissue-PO2, PCO2, and pH in patients with intracranial hypertension. Acta Neurochir Suppl 71:62–65PubMed
63.
go back to reference Smith MJ, Stiefel MF, Magge S, Frangos S, Bloom S, Gracias V, Le Roux PD (2005) Packed red blood cell transfusion increases local cerebral oxygenation. Crit Care Med 33:1104–1108PubMedCrossRef Smith MJ, Stiefel MF, Magge S, Frangos S, Bloom S, Gracias V, Le Roux PD (2005) Packed red blood cell transfusion increases local cerebral oxygenation. Crit Care Med 33:1104–1108PubMedCrossRef
64.
go back to reference Soehle M, Jaeger M, Meixensberger J (2003) Online assessment of brain tissue oxygen autoregulation in traumatic brain injury and subarachnoid hemorrhage. Neurol Res 25:411–417PubMedCrossRef Soehle M, Jaeger M, Meixensberger J (2003) Online assessment of brain tissue oxygen autoregulation in traumatic brain injury and subarachnoid hemorrhage. Neurol Res 25:411–417PubMedCrossRef
65.
go back to reference Stiefel MF, Heuer GG, Abrahams JM, Bloom S, Smith MJ, Maloney-Wilensky E, Grady MS, LeRoux PD (2004) The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage. J Neurosurg 101:594–599PubMed Stiefel MF, Heuer GG, Abrahams JM, Bloom S, Smith MJ, Maloney-Wilensky E, Grady MS, LeRoux PD (2004) The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage. J Neurosurg 101:594–599PubMed
66.
go back to reference Stiefel MF, Heuer GG, Smith MJ, Bloom S, Maloney-Wilensky E, Gracias VH, Grady MS, LeRoux PD (2004) Cerebral oxygenation following decompressive hemicraniectomy for the treatment of refractory intracranial hypertension. J Neurosurg 101:241–247PubMed Stiefel MF, Heuer GG, Smith MJ, Bloom S, Maloney-Wilensky E, Gracias VH, Grady MS, LeRoux PD (2004) Cerebral oxygenation following decompressive hemicraniectomy for the treatment of refractory intracranial hypertension. J Neurosurg 101:241–247PubMed
67.
go back to reference Stiefel MF, Spiotta A, Gracias VH, Garuffe AM, Guillamondegui O, Maloney-Wilensky E, Bloom S, Grady MS, LeRoux PD (2005) Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg 103:805–811PubMed Stiefel MF, Spiotta A, Gracias VH, Garuffe AM, Guillamondegui O, Maloney-Wilensky E, Bloom S, Grady MS, LeRoux PD (2005) Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg 103:805–811PubMed
68.
go back to reference Strege RJ, Lang EW, Stark AM, Scheffner H, Fritsch MJ, Barth H, Mehdorn HM (2003) Cerebral edema leading to decompressive craniectomy: an assessment of the preceding clinical and neuromonitoring trends. Neurol Res 25:510–515PubMedCrossRef Strege RJ, Lang EW, Stark AM, Scheffner H, Fritsch MJ, Barth H, Mehdorn HM (2003) Cerebral edema leading to decompressive craniectomy: an assessment of the preceding clinical and neuromonitoring trends. Neurol Res 25:510–515PubMedCrossRef
69.
go back to reference Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR (2004) Normobaric hyperoxia-induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study. J Neurosurg 101:435–444PubMedCrossRef Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR (2004) Normobaric hyperoxia-induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study. J Neurosurg 101:435–444PubMedCrossRef
70.
go back to reference Unterberg AW, Kiening KL, Hartl R, Bardt T, Sarrafzadeh AS, Lanksch WR (1997) Multimodal monitoring in patients with head injury: evaluation of the effects of treatment on cerebral oxygenation. J Trauma 42:S32–S37PubMed Unterberg AW, Kiening KL, Hartl R, Bardt T, Sarrafzadeh AS, Lanksch WR (1997) Multimodal monitoring in patients with head injury: evaluation of the effects of treatment on cerebral oxygenation. J Trauma 42:S32–S37PubMed
71.
go back to reference Unterberg AW, Sarrafzadeh AS, Lanksch WR (1999) Skull-brain injury in polytrauma-results of neurosurgery (in German). Anasthesiol Intensivmed Notfallmed Schmerzther 34(Suppl 1):S13–S19PubMed Unterberg AW, Sarrafzadeh AS, Lanksch WR (1999) Skull-brain injury in polytrauma-results of neurosurgery (in German). Anasthesiol Intensivmed Notfallmed Schmerzther 34(Suppl 1):S13–S19PubMed
72.
go back to reference Valadka AB, Gopinath SP, Contant CF, Uzura M, Robertson CS (1998) Relationship of brain tissue PO2 to outcome after severe head injury. Crit Care Med 26:1576–1581PubMedCrossRef Valadka AB, Gopinath SP, Contant CF, Uzura M, Robertson CS (1998) Relationship of brain tissue PO2 to outcome after severe head injury. Crit Care Med 26:1576–1581PubMedCrossRef
73.
go back to reference van Santbrink H, Maas AI, Avezaat CJ (1996) Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurgery 38:21–31PubMedCrossRef van Santbrink H, Maas AI, Avezaat CJ (1996) Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurgery 38:21–31PubMedCrossRef
74.
go back to reference van Santbrink H, Schouten JW, Steyerberg EW, Avezaat CJ, Maas AI (2002) Serial transcranial Doppler measurements in traumatic brain injury with special focus on the early posttraumatic period. Acta Neurochir (Wien) 144:1141–1149CrossRef van Santbrink H, Schouten JW, Steyerberg EW, Avezaat CJ, Maas AI (2002) Serial transcranial Doppler measurements in traumatic brain injury with special focus on the early posttraumatic period. Acta Neurochir (Wien) 144:1141–1149CrossRef
75.
go back to reference Wilensky EM, Bloom S, Leichter D, Verdiramo AM, Ledwith M, Stiefel M, LeRoux P, Grady MS (2005) Brain tissue oxygen practice guidelines using the LICOX CMP monitoring system. J Neurosci Nurs 37:278–288PubMedCrossRef Wilensky EM, Bloom S, Leichter D, Verdiramo AM, Ledwith M, Stiefel M, LeRoux P, Grady MS (2005) Brain tissue oxygen practice guidelines using the LICOX CMP monitoring system. J Neurosci Nurs 37:278–288PubMedCrossRef
Metadata
Title
Direct cerebral oxygenation monitoring—a systematic review of recent publications
Authors
Erhard W. Lang
Jamin M. Mulvey
Yugan Mudaliar
Nicholas W. C. Dorsch
Publication date
01-04-2007
Publisher
Springer-Verlag
Published in
Neurosurgical Review / Issue 2/2007
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-006-0062-4

Other articles of this Issue 2/2007

Neurosurgical Review 2/2007 Go to the issue