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Critical Care
Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Dipyridamole modulates the innate immune response during human endotoxemia

Authors: B Ramakers, NP Riksen, TH Stal, S Heemskerk, P Van den Broek, JG Van der Hoeven, P Smits, P Pickkers

Published in: Critical Care | Special Issue 1/2011

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Excerpt

Previous studies have shown that the endogenous nucleoside adenosine is able to modulate inflammation and to prevent associated organ injury. Dipyridamole, an adenosine re-uptake inhibitor, increases extracellular adenosine concentrations during unfavorable conditions (for example, inflammation), and as such may modulate the inflammatory response. We examined the effects of dipyridamole treatment on innate immunity during human experimental endotoxemia. …
Metadata
Title
Dipyridamole modulates the innate immune response during human endotoxemia
Authors
B Ramakers
NP Riksen
TH Stal
S Heemskerk
P Van den Broek
JG Van der Hoeven
P Smits
P Pickkers
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9686

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