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01-08-2011 | Brief Report

Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE)

Authors: Kazuhide Ohta, Tadafumi Yokoyama, Masaki Shimizu, Kazunori Mizuno, Shinobu Sakazume, Takuma Fujiki, Yutaka Saikawa, Akihiro Yachie

Published in: Pediatric Nephrology | Issue 8/2011

Abstract

Acute renal failure with severe loin pain induced by anaerobic exercise (ALPE) is a rare condition that is accompanied by wedge-shaped contrast enhancement on computed tomography (CT) without evidence of rhabdomyolysis. In two pediatric cases with ALPE, we tried to determine the relationship between findings from CT and magnetic resonance imaging (MRI). Case 1 involved a 13-year-old Japanese girl with a diagnosis of ALPE with normo-uricemia. Contrast-enhanced CT after 24 and 48 h showed a wedge-shaped excretion delay for the contrast media. A clear wedge-shaped signal hyperintensity matching the CT images was obtained by diffusion-weighted MRI. Case 2 involved a 16-year-old boy who presented with a second attack of ALPE after diagnosis of ALPE with hypouricemia 1 year earlier. Only diffusion-weighted imaging was performed. Clear wedge-shaped signal hyperintensity was apparent, similar to Case 1. MRI is safer than contrast-enhanced CT for patients with ALPE. Diffusion-weighted MRI is a very useful examination for diagnosing ALPE, providing noninvasive detection of lesions peculiar to ALPE.

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Title: Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE)
Authors: Kazuhide Ohta
Tadafumi Yokoyama
Masaki Shimizu
Kazunori Mizuno
Shinobu Sakazume
Takuma Fujiki
Yutaka Saikawa
Akihiro Yachie
Publication date: 01-08-2011
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 8/2011
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-011-1869-y

At a glance: The STEP trials

Springer Medicine

Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE)

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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