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International Journal of Hematology
Published in: International Journal of Hematology 1/2009

01-01-2009 | Images in Hematology

Diffuse large B-cell lymphoma with florid hemophagocytosis

Authors: David R. Czuchlewski, Susan L. Oupadia, Qian-Yun Zhang

Published in: International Journal of Hematology | Issue 1/2009

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Excerpt

A 66-year-old woman presented with progressive anemia and, over the course of several months, supervening pancytopenia. The peripheral smear showed marked anisopoikilocytosis with rare spherocytes and schistocytes. A direct antiglobulin test was positive. A bone marrow biopsy showed only mild megakaryocytic hyperplasia; the karyotype was normal. CT scan revealed marked splenomegaly (20 cm) with multiple masses measuring up to 4.7 cm in greatest dimension. …
Literature
1.
Hirai H, Shimazaki C, Hatsuse M, Okano A, Ashihara E, Inaba T, et al. Autologous peripheral blood stem cell transplantation for adult patients with B-cell lymphoma-associated hemophagocytic syndrome. Leukemia. 2001;15:311–2. doi:10.​1038/​sj.​leu.​2402030.CrossRefPubMed
2.
Shimazaki C, Inaba T, Nakagawa M. B-cell lymphoma-associated hemophagocytic syndrome. Leuk Lymphoma. 2000;38:121–30.PubMed
Metadata
Title
Diffuse large B-cell lymphoma with florid hemophagocytosis
Authors
David R. Czuchlewski
Susan L. Oupadia
Qian-Yun Zhang
Publication date
01-01-2009
Publisher
Springer Japan
Published in
International Journal of Hematology / Issue 1/2009
Print ISSN: 0925-5710
Electronic ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-008-0238-5

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