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Cancer Causes & Control
Published in: Cancer Causes & Control 5/2011

01-05-2011 | Original paper

Dietary habits and gastric cancer risk in north-west Iran

Authors: Mohammadreza Pakseresht, David Forman, Reza Malekzadeh, Abbas Yazdanbod, Robert M. West, Darren C. Greenwood, Jean E. Crabtree, Janet E. Cade

Published in: Cancer Causes & Control | Issue 5/2011

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Abstract

Objectives

North-west Iran is a high-risk area for gastric cancer (GC). Dietary practices may increase risk of GC. For the first time, the diet–GC association in this area was assessed using a validated food frequency questionnaire.

Methods

Cases and controls were recruited in a population-based study. In addition to collecting dietary data using a food frequency questionnaire, Helicobacter pylori antibody level was measured. Multiple logistic regression models were used to estimate odds ratios for associations between dietary factors and GC among 286 cases and 304 controls.

Results

A positive association was estimated for total fat intake (OR = 1.33/20 g, 95% CI: 1.12–1.57) and risk of GC. Inverse associations were observed for vitamin C, iron, and zinc intake and risk of GC and its subgroups (cardia, non-cardia). Fruits and vegetables consumption and refrigerator use showed inverse associations (OR = 0.72/100 g, 95% CI: 0.65–0.80 and OR = 0.75/10 years, 95% CI: 0.60–0.95, respectively). Positive association was observed among those who preferred fried food (OR = 2.21, 95% CI: 1.45–3.37) or consumed highly salted/roasted seeds (OR = 1.97, 95% CI: 1.13–3.43).

Conclusion

GC in north-west Iran is associated with dietary practices: foods, nutrients and food preparation habits.
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Metadata
Title
Dietary habits and gastric cancer risk in north-west Iran
Authors
Mohammadreza Pakseresht
David Forman
Reza Malekzadeh
Abbas Yazdanbod
Robert M. West
Darren C. Greenwood
Jean E. Crabtree
Janet E. Cade
Publication date
01-05-2011
Publisher
Springer Netherlands
Published in
Cancer Causes & Control / Issue 5/2011
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-011-9744-5

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