Published in:
Open Access
01-12-2023 | Research
Dietary fatty acid patterns and risk of metabolic syndrome: Tehran lipid and glucose study
Authors:
Parvin Mirmiran, Zahra Gaeini, Zahra Feizy, Fereidoun Azizi
Published in:
European Journal of Medical Research
|
Issue 1/2023
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Abstract
Background
The association between individual dietary fatty acids (FAs) and risk of metabolic syndrome (MetS) has been investigated in previous studies. However, synergistic or additive effects of multiple FA have received less attention. Hence, we aimed to determine the major dietary FA patterns and evaluate the association between FA patterns and risk of MetS.
Methods
Dietary intakes of 1713 MetS-free adults who participated in the third phase of the Tehran Lipid and Glucose Study (TLGS) were assessed using a validated 168-items food frequency questionnaire. FA patterns were obtained by principal component analysis (PCA). Adjusted Hazard Ratios (HRs) and 95% confidence intervals (CIs) were calculated for the association of MetS incident with the extracted FA patterns.
Results
Four major FA patterns were identified through PCA of the 24 FAs consumed: “short- and medium-chain saturated fatty acid (SFA) pattern”, “long-chain FA pattern”, “omega-3 PUFA pattern”, and “long-chain SFA pattern”. There was no significant association between dietary FA patterns and risk of MetS incidence.
Conclusions
We found no significant association between FA patterns and risk of MetS. More prospective cohort studies and clinical trials are needed to clarify the issue.