Top

Published in:

01-06-2005

Diagnostic Value of Measuring Liver Volume for Detecting Occult Hepatic Metastases from Colorectal or Gastric Cancer

Authors: Takeaki Ishizawa, M.D., Tetsuhisa Yamamoto, M.D., Ph.D., Koichiro Nishida, M.D., Hajime Tsukui, M.D., Takayoshi Sekikawa, M.D., Ph.D.

Published in: World Journal of Surgery | Issue 6/2005

Abstract

Some studies have shown reduced portal blood flow in patients with occult hepatic metastases, which may lead to decreased liver volume. A retrospective study was conducted in patients undergoing curative resection for colorectal (n = 63) or gastric (n = 52) cancer. The ratio of the preoperative computed tomography (CT)-estimated liver volume to the standard liver volume (CV/SV ratio) was calculated. The mean ± SD CT-estimated liver volume was 858 ±109 in 14 patients who subsequently developed hepatic metastases and 1173 ± 230 ml in 101 patients without metastases (p < 0.0001). The CV/SV ratio was smaller in patients with metachronous hepatic metastases than in those without (0.78 ± 0.08 vs. 1.02 + 0.13; p < 0.0001). The results suggest that the liver with occult metastases decreases in size before metastases develop that are detectable using conventional imaging techniques. The CV/SV ratio may be of value in detecting occult hepatic metastases from colorectal and gastric cancer.

National Institute of Health Consensus Development Conference.1990Adjuvant therapy for patients with colon, rectal cancerJ.A.M.A.26414441450

Koizumi, W, Kurihara, M, Nakano, S, et al. 2000Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancerOncology58191197CrossRefPubMed

Minagawa, M, Makuuchi, M, Torzilli, G, et al. 2000Extension of the frontiers of surgical indication in the treatment of liver metastases from colorectal cancerAnn. Surg.231487499CrossRefPubMed

Sakamoto, Y, Ohyama, S, Yamamoto, J, et al. 2003Surgical resection of liver metastases of gastric cancer: an analysis of a 17-year experience with 22 patientsSurgery133507511CrossRefPubMed

Leveson, SH, Wiggins, PA, Giles, GR, et al. 1985Deranged liver blood flow patterns in the detection of liver metastasesBr. J. Surg.72128130PubMed

Hemingway, DM, Cooke, TG, Grime, SJ, et al. 1991Changes in hepatic haemodynamics and the hepatic perfusion index during the growth and development of hypo vascular HSN sarcoma in ratsBr. J. Surg.78362370

Leen, E, Goldburg, JA, Robertson, J, et al. 1993Early detection of occult colorectal hepatic metastases using duplex colour Doppler sonographyBr. J. Surg.8012491251PubMed

Leen, E, Angerson, WJ, Wotherspoon, H, et al. 1994Comparison of Doppler perfusion index and intraoperative ultrasonography in diagnosing colorectal liver metastases: evaluation with postoperative follow-up resultsAnn. Surg.220663667PubMed

Leen, E, Anderson, JR, Robertson, J, et al. 1997Doppler perfusion index in the detection of hepatic metastases secondary to gastric carcinomaAm. J. Surg.17399102CrossRefPubMed

10.

Shuman, WP 1995Liver metastases from colorectal carcinoma: detection with Doppler US-guided measurements of liver blood flow: past, present, future [editorial]Radiology195910PubMed

11.

Fowler, RC, Harris, KM, Swift, SE, et al. 1998Hepatic Doppler perfusion index: measurement in nine healthy volunteersRadiology209867871PubMed

12.

Rous, P, Larimore, LD 1920Relation of the portal blood to liver maintenance: a demonstration of liver atrophy conditional on compensationJ. Exp. Med.31609632CrossRef

13.

Schalm, L, Bax, HR, Mansens, BJ 1956Atrophy of the liver after occlusion of the bile ducts or portal vein and compensatory hypertrophy of the unoccluded portion and its clinical importanceGastroenterology31131155PubMed

14.

Rozga, J, Jeppsson, B, Bengmark, S 1986Hepatotropic effect of portal blood during hepatic arterial recirculationEur. Surg. Res.18302311PubMed

15.

Takayasu, K, Muramatsu, Y, Shima, Y, et al. 1986Hepatic lobar atrophy following obstruction of the ipsilateral portal vein from hilar cholangiocarcinomaRadiology160389393PubMed

16.

Urata, K, Kawasaki, S, Matsunami, H, et al. 1995Calculation of child and adult standard liver volume for liver transplantationHepatology2113171321CrossRefPubMed

17.

DuBois, D, DuBois, EF 1916A formula to estimate the approximate surface area if height and weight be knownArch. Intern. Med.17863871

18.

Heymsfield, SB, Fulenwider, T, Nordlinger, B, et al. 1979Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomographyAnn. Intern. Med.90185187PubMed

19.

Henderson, JM, Heymsfield, SB, Horowitz, J, et al. 1981Measurement of liver and spleen volume by computed tomographyRadiology141525527PubMed

20.

Schiano, TD, Bodian, C, Schwartz, ME, et al. 2000Accuracy and significance of computed tomographic scan assessment of hepatic volume in patients undergoing liver transplantationTransplantation69545550CrossRefPubMed

21.

Soyer, P, Roche, A, Elias, D, et al. 1992Hepatic metastases from colorectal cancer: influence of hepatic volumetric analysis on surgical decision makingRadiology184695697PubMed

22.

Kubota, K, Makuuchi, M, Kusaka, K, et al. 1997Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional surgery for hepatic tumorsHepatology2611761181PubMed

23.

Kawasaki, S, Makuuchi, M, Matsunami, H, et al. 1993Preoperative measurement of segmental liver volume of donors for living related liver transplantationHepatology1811151120CrossRefPubMed

24.

Kamel, IR, Kruskal, JB, Warmbrand, G, et al. 2001Accuracy of volumetric measurements after virtual right hepatectomy in potential donor undergoing living adult liver transplantationA.J.R. Am. J. Roentgenol.176483487

25.

Urata, K, Hashikura, T, Ikegami, T, et al. 2000Standard liver volume in adultsTransplant. Proc.3220932094CrossRefPubMed

26.

Kawasaki, S, Makuuchi, M, Matsunami, H, et al. 1998Living related liver transplantation in adultsAnn. Surg.227269274CrossRefPubMed

27.

Nishizaki, T, Ikegami, T, Hiroshige, S, et al. 2001Small graft for living donor liver transplantationAnn. Surg.233575580CrossRefPubMed

28.

Vauthey, JN, Chaoui, A, Do, KA, et al. 2000Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associationsSurgery127512519CrossRefPubMed

29.

Deland, FH, North, WA 1968Relationship between liver size and body sizeRadiology9111951198PubMed

30.

Marchesini, G, Bua, V, Brunori, A, et al. 1988Galactose elimination capacity and liver volume in aging manHepatology810791083PubMed

31.

Wynne, HA, Cope, LH, Mutch, M, et al. 1989The effect of age upon liver volume and apparent liver blood flow in healthy manHepatology9297301PubMed

32.

Walk, L 1981Liver size in hepatobiliary disease and in jejuno-ileal bypassHepatogastroenterology282730PubMed

33.

Lin, XZ, Sun, YN, Liu, YH, et al. 1998Liver volume in patients with and without chronic liver diseaseHepatogastroenterology4510691074PubMed

34.

Ueno, H, Mochizuki, H, Hatsuse, K, et al. 2000Indications for treatment strategies of colorectal liver metastasesAnn. Surg.2315966CrossRefPubMed

35.

Ohno, S, Fujii, T, Ueda, S, et al. 2003Predictive factor and timing for liver recurrence after curative resection of gastric carcinomaAm. J. Surg.185258263CrossRefPubMed

36.

Bilodeau, M, Aubry, MC, Houle, R, et al. 1999Evaluation of hepatocyte injury following partial ligation of the left portal veinJ. Hepatol.302937CrossRefPubMed

37.

Rocheleau, B, Éthier, C, Houle, R, et al. 1999Hepatic artery buffer response following left portal vein ligation: its role in liver tissue homeostasisAm. J. Physiol.277G1000G1007PubMed

38.

Purkiss, SF, Williams, NS 1993Growth rate and percentage hepatic replacement of colorectal liver metastasesBr. J. Surg.8010361038PubMed

39.

Dworkin, MJ, Burke, D, Earlam, S, et al. 1998Measurement of response to treatment in colorectal liver metastasesBr. J. Cancer71873876

Title: Diagnostic Value of Measuring Liver Volume for Detecting Occult Hepatic Metastases from Colorectal or Gastric Cancer
Authors: Takeaki Ishizawa, M.D.
Tetsuhisa Yamamoto, M.D., Ph.D.
Koichiro Nishida, M.D.
Hajime Tsukui, M.D.
Takayoshi Sekikawa, M.D., Ph.D.
Publication date: 01-06-2005
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 6/2005
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-005-7888-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diagnostic Value of Measuring Liver Volume for Detecting Occult Hepatic Metastases from Colorectal or Gastric Cancer

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 6/2005

Adult Surgical Emergencies in a Developing Country: The Experience of Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria

Safety and Effectiveness of Left Hepatic Trisegmentectomy for Hilar Cholangiocarcinoma

Inhibition of Gastric Cancer Cell Adhesion in Nude Mice by Inraperitoneal Phospholipids

Reply

Use of Ligasure in Thyroidectomy Procedures: Results of a Prospective Comparative Study

Effect of Radiofrequency Ablation of the Liver on Cell-Mediated Immunity in Rats