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Published in:

01-09-2011

Diagnostic Thresholds in Osteoporosis: How Are They Used in Clinical Trials?

Authors: Ronald C. Hamdy, Dustin M. Price, Miriam M. Mottl

Published in: Current Osteoporosis Reports | Issue 3/2011

Abstract

Clinical trials are used to determine the efficacy and safety of a medication prior to approval for commercial use and to influence the prescribing habits of clinicians. The lack of uniformity in the diagnostic thresholds used in clinical trials on osteoporosis makes it difficult to compare the results of these trials. The use of placebo, different anatomical sites, T-score cutoff points, and risk factors precludes any meaningful comparison being made between the outcomes of clinical trials. Finally, the lack of uniform reporting format makes it difficult to retrieve important information to compare one medication to another. Because the diagnostic thresholds used affect the outcomes of these trials, health care providers need to be aware of these criteria to determine whether the results of a particular clinical trial can be applied to a particular patient.

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Title: Diagnostic Thresholds in Osteoporosis: How Are They Used in Clinical Trials?
Authors: Ronald C. Hamdy
Dustin M. Price
Miriam M. Mottl
Publication date: 01-09-2011
Publisher: Current Science Inc.
Published in: Current Osteoporosis Reports / Issue 3/2011
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-011-0063-2

Keynote webinar | Spotlight on medication adherence

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Diagnostic Thresholds in Osteoporosis: How Are They Used in Clinical Trials?

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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