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European Radiology

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01-07-2017 | Computed Tomography

Diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction algorithm for the detection of hypervascular liver lesions: a phantom study

Authors: Atsushi Nakamoto, Yoshikazu Tanaka, Hiroshi Juri, Go Nakai, Shushi Yoshikawa, Yoshifumi Narumi

Published in: European Radiology | Issue 7/2017

Abstract

Objectives

To investigate the diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction (IR) algorithm for the detection of hypervascular liver lesions.

Methods

Thirty liver phantoms with or without simulated hypervascular lesions were scanned with a 320-slice CT scanner with control-dose (40 mAs) and reduced-dose (30 and 20 mAs) settings. Control-dose images were reconstructed with filtered back projection (FBP), and reduced-dose images were reconstructed with FBP and a hybrid IR algorithm. Objective image noise and the lesion to liver contrast-to-noise ratio (CNR) were evaluated quantitatively. Images were interpreted independently by 2 blinded radiologists, and jackknife alternative free-response receiver-operating characteristic (JAFROC) analysis was performed.

Results

Hybrid IR images with reduced-dose settings (both 30 and 20 mAs) yielded significantly lower objective image noise and higher CNR than control-dose FBP images (P < .05). However, hybrid IR images with reduced-dose settings had lower JAFROC1 figure of merit than control-dose FBP images, although only the difference between 20 mAs images and control-dose FBP images was significant for both readers (P < .01).

Conclusions

An aggressive reduction of the radiation dose would impair the detectability of hypervascular liver lesions, although objective image noise and CNR would be preserved by a hybrid IR algorithm.

Key points

• A half-dose scan with a hybrid iterative reconstruction preserves objective image quality.

• A hybrid iterative reconstruction algorithm does not improve diagnostic performance.

• An aggressive dose reduction would impair the detectability of low-contrast lesions.

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Title: Diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction algorithm for the detection of hypervascular liver lesions: a phantom study
Authors: Atsushi Nakamoto
Yoshikazu Tanaka
Hiroshi Juri
Go Nakai
Shushi Yoshikawa
Yoshifumi Narumi
Publication date: 01-07-2017
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 7/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-016-4687-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction algorithm for the detection of hypervascular liver lesions: a phantom study

Abstract

Objectives

Methods

Results

Conclusions

Key points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key points

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