Published in:
Open Access
01-12-2012 | Poster presentation
Diagnosis of post-transplant coronary artery disease using contrast-enhanced coronary vessel wall imaging at 3.0 Tesla
Authors:
Tarique Hussain, Matthew Fenton, Sarah A Peel, Andrea Wiethoff, Rene M Botnar, Michael Burch, Gerald F Greil
Published in:
Journal of Cardiovascular Magnetic Resonance
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Special Issue 1/2012
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Excerpt
Coronary plaque characterization at 3.0 Tesla holds great potential for clinical benefit. Coronary allograft vasculopathy (CAV) occurs after heart transplantation and is an immune-mediated diffuse coronary intimal disease. We demonstrate the use of contrast-enhanced inversion-recovery prepared coronary vessel wall MRI at 3T for diagnosis. We further validate the technique in 23 patients with intravascular ultrasound (IVUS), showing an accuracy of 91%. Direct non-invasive imaging has great potential benefit for screening and prevention in these patients. The study has further significant implications for conventional coronary atherosclerosis. …