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Open Access 01-12-2015 | Review

Diagnosis and management of inhalation injury: an updated review

Authors: Patrick F. Walker, Michelle F. Buehner, Leslie A. Wood, Nathan L. Boyer, Ian R. Driscoll, Jonathan B. Lundy, Leopoldo C. Cancio, Kevin K. Chung

Published in: Critical Care | Issue 1/2015

Abstract

In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest computed tomography may allow for a more nuanced evaluation of inhalation injury and enhanced ability to prognosticate. Supportive respiratory care remains essential in managing inhalation injury. Adjuncts still lacking definitive evidence of efficacy include bronchodilators, mucolytic agents, inhaled anticoagulants, nonconventional ventilator modes, prone positioning, and extracorporeal membrane oxygenation. Recent research focusing on molecular mechanisms involved in inhalation injury has increased the number of potential therapies.

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Title: Diagnosis and management of inhalation injury: an updated review
Authors: Patrick F. Walker
Michelle F. Buehner
Leslie A. Wood
Nathan L. Boyer
Ian R. Driscoll
Jonathan B. Lundy
Leopoldo C. Cancio
Kevin K. Chung
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Critical Care / Issue 1/2015
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-015-1077-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diagnosis and management of inhalation injury: an updated review

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

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