Published in:
Open Access
01-12-2014 | Meeting abstract
Diagnosing penicillin allergy in the absence of minor determinant mixture
Authors:
Lana Rosenfield, Chrystyna Kalicinsky, Richard Warrington
Published in:
Allergy, Asthma & Clinical Immunology
|
Special Issue 2/2014
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Excerpt
Penicillin allergy is a common presentation in allergy clinic. The diagnosis of immediate hypersensitivity is made using clinical history, skin testing, specific IgE levels and oral challenge. Skin testing is done using benzyl penicilloyl-polylysine (PPL) and a minor determinant mixture (MDM) consisting of penicillin byproducts. Although using PPL and MDM is considered first line for diagnosis [
1], our clinic is unable to consistently obtain MDM. We have undertaken a retrospective chart review to assess our current protocol in diagnosing penicillin allergy using Penicillin G (PG) alone instead of MDM. …