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Published in: Allergy, Asthma & Clinical Immunology 2/2014

Open Access 01-12-2014 | Meeting abstract

Diagnosing penicillin allergy in the absence of minor determinant mixture

Authors: Lana Rosenfield, Chrystyna Kalicinsky, Richard Warrington

Published in: Allergy, Asthma & Clinical Immunology | Special Issue 2/2014

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Excerpt

Penicillin allergy is a common presentation in allergy clinic. The diagnosis of immediate hypersensitivity is made using clinical history, skin testing, specific IgE levels and oral challenge. Skin testing is done using benzyl penicilloyl-polylysine (PPL) and a minor determinant mixture (MDM) consisting of penicillin byproducts. Although using PPL and MDM is considered first line for diagnosis [1], our clinic is unable to consistently obtain MDM. We have undertaken a retrospective chart review to assess our current protocol in diagnosing penicillin allergy using Penicillin G (PG) alone instead of MDM. …
Literature
1.
go back to reference Romano A, Bousquet-Rouanet L, Viola M, Gaeta F, Demoly P, Bousquet PJ: Benzylpenicillin skin testing is still important in diagnosing immediate hypersensitivity reactions to penicillins. Allergy. 2009, 64: 249-253. 10.1111/j.1398-9995.2008.01874.x.CrossRefPubMed Romano A, Bousquet-Rouanet L, Viola M, Gaeta F, Demoly P, Bousquet PJ: Benzylpenicillin skin testing is still important in diagnosing immediate hypersensitivity reactions to penicillins. Allergy. 2009, 64: 249-253. 10.1111/j.1398-9995.2008.01874.x.CrossRefPubMed
Metadata
Title
Diagnosing penicillin allergy in the absence of minor determinant mixture
Authors
Lana Rosenfield
Chrystyna Kalicinsky
Richard Warrington
Publication date
01-12-2014
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1710-1492-10-S2-A43

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