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Published in: Diabetologia 9/2005

01-09-2005 | Commentary

Diabetes and pregnancy: beyond glucose?

Author: C. Mathieu

Published in: Diabetologia | Issue 9/2005

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Excerpt

Many readers will know what it is like to be called to a delivery room when one of your patients with type 1 diabetes has just given birth to a macrosomic baby. The eyes of all around will accuse you of poor glucose control. So you go back to scan the file and find that this patient had a set of excellent HbA1c results. You may now be ready to believe that glucose control, especially mean glycaemic control, is not the only factor that determines the outcome of pregnancy in a woman with diabetes. …
Literature
1.
go back to reference Kitzmiller JL, Buchanan TA, Kjos S, Combs CA, Ratner RE (1996) Pre-conception care of diabetes, congenital malformations and spontaneous abortions. Diabetes Care 19:514–541PubMed Kitzmiller JL, Buchanan TA, Kjos S, Combs CA, Ratner RE (1996) Pre-conception care of diabetes, congenital malformations and spontaneous abortions. Diabetes Care 19:514–541PubMed
2.
go back to reference Ray JG, O’Brien TE, Chan WS (2001) Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus. QJM 94:435–444CrossRefPubMed Ray JG, O’Brien TE, Chan WS (2001) Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus. QJM 94:435–444CrossRefPubMed
3.
go back to reference DCCT Investigators (1996) Pregnancy outcomes in the Diabetes Control and Complications Trial. Am J Obstet Gynecol 174:1343–1353 DCCT Investigators (1996) Pregnancy outcomes in the Diabetes Control and Complications Trial. Am J Obstet Gynecol 174:1343–1353
4.
go back to reference Heilig CW, Saunders T, Brosius FC et al (2003) Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc Natl Acad Sci U S A 100:15613–15618CrossRefPubMed Heilig CW, Saunders T, Brosius FC et al (2003) Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc Natl Acad Sci U S A 100:15613–15618CrossRefPubMed
5.
go back to reference Kovilam O, Khoury J, Miodovnik M, Chames M, Spinnoto J, Sibai B (2002) Spontaneous preterm delivery in the type 1 diabetic pregnancy: the role of glycemic control. J Matern Fetal Neonatal Med 11:245–248PubMed Kovilam O, Khoury J, Miodovnik M, Chames M, Spinnoto J, Sibai B (2002) Spontaneous preterm delivery in the type 1 diabetic pregnancy: the role of glycemic control. J Matern Fetal Neonatal Med 11:245–248PubMed
6.
go back to reference Hudelist G, Gelle’n J, Singer C et al (2005) Factors predicting severe perineal trauma during childbirth: role of forceps delivery routinely combined with mediolateral episiotomy. Am J Obstet Gynecol 192:875–881CrossRefPubMed Hudelist G, Gelle’n J, Singer C et al (2005) Factors predicting severe perineal trauma during childbirth: role of forceps delivery routinely combined with mediolateral episiotomy. Am J Obstet Gynecol 192:875–881CrossRefPubMed
7.
go back to reference Boney CM, Verma A, Tucker R, Vohr BR (2005) Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 115:290–296CrossRef Boney CM, Verma A, Tucker R, Vohr BR (2005) Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 115:290–296CrossRef
8.
go back to reference Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group (2005) Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med 352:2477–2486CrossRefPubMed Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group (2005) Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med 352:2477–2486CrossRefPubMed
9.
go back to reference Workshop Report (1990) Diabetes care and research in Europe: the Saint Vincent declaration. Diabet Med 7:360PubMed Workshop Report (1990) Diabetes care and research in Europe: the Saint Vincent declaration. Diabet Med 7:360PubMed
10.
go back to reference Casson IF, Clarke CA, Howard CV et al (1997) Outcomes of pregnancy in insulin dependent diabetic women: results of a 5-year population cohort study. BMJ 315:275–278PubMed Casson IF, Clarke CA, Howard CV et al (1997) Outcomes of pregnancy in insulin dependent diabetic women: results of a 5-year population cohort study. BMJ 315:275–278PubMed
11.
go back to reference Boulot P, Chabbert-Buffet N, d’Ercole C et al (2003) French multicentric survey of outcome of pregnancy in women with pregestational diabetes. Diabetes Care 26:2990–2993PubMed Boulot P, Chabbert-Buffet N, d’Ercole C et al (2003) French multicentric survey of outcome of pregnancy in women with pregestational diabetes. Diabetes Care 26:2990–2993PubMed
12.
go back to reference Combs CA, Gunderson E, Kitzmiller JL, Gavin LA, Main EK (1992) Relationship of fetal macrosomia to maternal postprandial glucose control during pregnancy. Diabetes Care 15:1251–1257PubMed Combs CA, Gunderson E, Kitzmiller JL, Gavin LA, Main EK (1992) Relationship of fetal macrosomia to maternal postprandial glucose control during pregnancy. Diabetes Care 15:1251–1257PubMed
13.
go back to reference Penney GC, Mair G, Pearson W (2003) The relationship between birth weight and maternal glycated haemoglobin (HbA1c) concentration in pregnancies complicated by type 1 diabetes. Diabet Med 20:162–166CrossRefPubMed Penney GC, Mair G, Pearson W (2003) The relationship between birth weight and maternal glycated haemoglobin (HbA1c) concentration in pregnancies complicated by type 1 diabetes. Diabet Med 20:162–166CrossRefPubMed
15.
16.
go back to reference Galerneau F, Inzucchi SE (2004) Diabetes mellitus in pregnancy. Obstet Gynecol Clin North Am 31:907–933CrossRefPubMed Galerneau F, Inzucchi SE (2004) Diabetes mellitus in pregnancy. Obstet Gynecol Clin North Am 31:907–933CrossRefPubMed
17.
go back to reference Ben-Haroush A, Yogev Y, Chen R, Rosenn B, Hod M, Langer O (2004) The postprandial glucose profile in the diabetic pregnancy. Am J Obs Gynecol 191:576–581CrossRef Ben-Haroush A, Yogev Y, Chen R, Rosenn B, Hod M, Langer O (2004) The postprandial glucose profile in the diabetic pregnancy. Am J Obs Gynecol 191:576–581CrossRef
Metadata
Title
Diabetes and pregnancy: beyond glucose?
Author
C. Mathieu
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 9/2005
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-005-1872-6

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