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Journal of Assisted Reproduction and Genetics

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01-05-2007 | Assisted Reproduction

Developmental prognosis for zygotes based on pronuclear pattern: Usefulness of pronuclear scoring

Authors: Gemma Arroyo, Anna Veiga, Josep Santaló, Pere Nolasc Barri

Published in: Journal of Assisted Reproduction and Genetics | Issue 5/2007

Abstract

Purpose: To relate pronuclear patterns (PN) and zygote cytoplasmic appearance and embryo morphology.

Methods: The usefulness of PN classification described by Tesarik et al. 1999 (patterns p0-5) and Scott et al. 2000 (Z1-4), for embryo selection is assessed.

Results: Sinchrony on polarization and number of nucleolar precursor bodies (NPB) were associated with good quality embryos (p0 60.9% and p3 67.3%, and Z1 62.5% and Z2 64.7%; p<0.01). Pattern 4 zygotes were associated with small number of NPB developed into multinucleated embryos (14.3%) and poor quality embryos (61.9%). No significant differences were found in the pregnancy rate between transfer of at least one good prognosis PN pattern and transfer of poor prognosis PN patterns, although 75% of the transfers included at least one embryo derived from a pattern 0 zygote, and 55% included embryos from categories Z1 or Z2.

Conclusions: Sequential assessment involving the evaluation of oocyte quality, the classification of PN patterns and embryo morphology allows a more accurate evaluation of embryos to be selected for transfer.

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Title: Developmental prognosis for zygotes based on pronuclear pattern: Usefulness of pronuclear scoring
Authors: Gemma Arroyo
Anna Veiga
Josep Santaló
Pere Nolasc Barri
Publication date: 01-05-2007
Publisher: Kluwer Academic Publishers-Plenum Publishers
Published in: Journal of Assisted Reproduction and Genetics / Issue 5/2007
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-006-9099-0

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Springer Medicine

Developmental prognosis for zygotes based on pronuclear pattern: Usefulness of pronuclear scoring

Abstract

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Abstract

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