Skip to main content
Top
Published in: BMC Infectious Diseases 1/2015

Open Access 01-12-2015 | Research article

Development of quality indicators and data assessment strategies for the prevention of central venous catheter-related bloodstream infections (CRBSI)

Authors: Anke Bramesfeld, Stephanie Wrede, Klaus Richter, Mareike Steen, Björn Broge, Jürgen Pauletzki, Joachim Szecsenyi

Published in: BMC Infectious Diseases | Issue 1/2015

Login to get access

Abstract

Background

The number of catheter related bloodstream infections (CRBSI) could be reduced and the outcome improved if specific standards in the quality of care were maintained. Therefore, the development of quality assurance (QA) procedures was commissioned to be included in the national mandatory QA programme in Germany.

Methods

Indicators representing quality deficiencies and potential for improvement of quality in relation to prevention and management of central venous catheters (CVC) were developed by 1) evidence-based literature searches and the compiling of an indicator register; 2) a multi-professional expert panel including patient representatives who selected indicators from this register by using a modified RAND/UCLA Appropriateness Method; 3) defining methods for data assessment, risk adjustment and feedback of indicator results to service providers; and 4) consulting all relevant medical societies and other stakeholders with regard to the QA procedures that had been developed.

Results

Thirty-two indicators for CRBSI prevention and management were eventually approved by the expert panel. These indicators represent quality of care at predefined points with regard to indication, insertion and care of CVCs, management of sepsis, general hygiene and training of health care personnel. Fourteen indicators represent processes, together with 7 representing structures and 11 outcomes. For assessing these indicators, data was obtained from four sources: claims data from health insurance funds, routine claims data from hospital electronic information systems, case specific longitudinal documentation from service providers and cross-sectional annual assessment of structures.

Conclusions

It was possible to develop indicators for mandatory QA procedures on CRBSI that take into account the different perspectives of all stakeholders involved. Despite efforts to use routine data for documentation wherever possible, most indicators required extra documentation.
Appendix
Available only for authorised users
Literature
1.
go back to reference Maki DG, Kluger DM, Crnich CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc. 2006;81(9):1159–71.CrossRefPubMed Maki DG, Kluger DM, Crnich CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc. 2006;81(9):1159–71.CrossRefPubMed
2.
go back to reference Gastmeier P, Sohr D, Geffers C, Behnke M, Ruden H. Risk factors for death due to nosocomial infection in intensive care unit patients: findings from the Krankenhaus Infektions Surveillance System. Infect Control Hosp Epidemiol. 2007;28(4):466–72.CrossRefPubMed Gastmeier P, Sohr D, Geffers C, Behnke M, Ruden H. Risk factors for death due to nosocomial infection in intensive care unit patients: findings from the Krankenhaus Infektions Surveillance System. Infect Control Hosp Epidemiol. 2007;28(4):466–72.CrossRefPubMed
3.
go back to reference Engel C, Brunkhorst FM, Bone HG, Brunkhorst R, Gerlach H, Grond S, et al. Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med. 2007;33(4):606–18.CrossRefPubMed Engel C, Brunkhorst FM, Bone HG, Brunkhorst R, Gerlach H, Grond S, et al. Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med. 2007;33(4):606–18.CrossRefPubMed
4.
go back to reference Murphy DJ, Needham DM, Goeschel C, Fan E, Cosgrove SE, Pronovost PJ. Monitoring and reducing central line-associated bloodstream infections: A national survey of state hospital associations. Am J Med Qual. 2010;25(4):255–60.CrossRefPubMed Murphy DJ, Needham DM, Goeschel C, Fan E, Cosgrove SE, Pronovost PJ. Monitoring and reducing central line-associated bloodstream infections: A national survey of state hospital associations. Am J Med Qual. 2010;25(4):255–60.CrossRefPubMed
5.
go back to reference Pronovost PJ, Goeschel CA, Colantuoni E, Watson S, Lubomski LH, Berenholtz SM, et al. Sustaining reductions in catheter related bloodstream infections in Michigan intensive care units: Observational study. BMJ. 2010;340(7744):462. Pronovost PJ, Goeschel CA, Colantuoni E, Watson S, Lubomski LH, Berenholtz SM, et al. Sustaining reductions in catheter related bloodstream infections in Michigan intensive care units: Observational study. BMJ. 2010;340(7744):462.
6.
go back to reference Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):2725–32.CrossRefPubMed Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):2725–32.CrossRefPubMed
7.
go back to reference Srinivasan A, Wise M, Bel M, Cardo D, Edwards J, Fridkin S, et al. Vital signs: Central line-associated blood stream infections – United States, 2001, 2008, and 2009. MMWR Recomm Rep. 2011;60(8):243–8. Srinivasan A, Wise M, Bel M, Cardo D, Edwards J, Fridkin S, et al. Vital signs: Central line-associated blood stream infections – United States, 2001, 2008, and 2009. MMWR Recomm Rep. 2011;60(8):243–8.
8.
go back to reference Vonberg RP, Groneberg K, Geffers C, Ruden H, Gastmeier P. Hygienemaßnahmen auf Intensivstationen: Ergebnisse des nationalen Krankenhaus-Infektions-Surveillance-Systems (KISS). Anaesthesist. 2005;54(10):975–82.CrossRefPubMed Vonberg RP, Groneberg K, Geffers C, Ruden H, Gastmeier P. Hygienemaßnahmen auf Intensivstationen: Ergebnisse des nationalen Krankenhaus-Infektions-Surveillance-Systems (KISS). Anaesthesist. 2005;54(10):975–82.CrossRefPubMed
9.
go back to reference Hansen S, Schwab F, Behnke M, Carsauw H, Heczko P, Klavs I, et al. National influences on catheter-associated bloodstream infection rates: practices among national surveillance networks participating in the European HELICS project. J Hosp Infect. 2009;71(1):66–73.CrossRefPubMed Hansen S, Schwab F, Behnke M, Carsauw H, Heczko P, Klavs I, et al. National influences on catheter-associated bloodstream infection rates: practices among national surveillance networks participating in the European HELICS project. J Hosp Infect. 2009;71(1):66–73.CrossRefPubMed
10.
go back to reference Willms G, Bramesfeld A, Pottkämper K, Broge B, Szecsenyi J. Aktuelle Herausforderungen der externen Qualitätssicherung im deutschen Gesundheitswesen. Z Evid Fortbild Qual Gesundhwes. 2013;107(8):523–7.CrossRefPubMed Willms G, Bramesfeld A, Pottkämper K, Broge B, Szecsenyi J. Aktuelle Herausforderungen der externen Qualitätssicherung im deutschen Gesundheitswesen. Z Evid Fortbild Qual Gesundhwes. 2013;107(8):523–7.CrossRefPubMed
11.
go back to reference AQUA. Tätigkeitsbericht 2012 im Rahmen der Aufgaben des §137a SGB V (Stand: 5. Mai 2013). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013. AQUA. Tätigkeitsbericht 2012 im Rahmen der Aufgaben des §137a SGB V (Stand: 5. Mai 2013). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013.
12.
go back to reference AQUA. Methodenpapier 3.0. Göttingen: AQUA — Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen GmbH; 2012. AQUA. Methodenpapier 3.0. Göttingen: AQUA — Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen GmbH; 2012.
13.
go back to reference Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LacCalle JR, Lazaro P et al. The RAND/UCLA Appropriateness Method User's Manual. Santa Monica: RAND; 2001. Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LacCalle JR, Lazaro P et al. The RAND/UCLA Appropriateness Method User's Manual. Santa Monica: RAND; 2001.
14.
go back to reference AQUA. Vermeidung nosokomialer Infektionen: Gefäßkatheter-assoziierte Infektionen. Abschlussbericht (Stand: 20.Dezember 2012). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2012. AQUA. Vermeidung nosokomialer Infektionen: Gefäßkatheter-assoziierte Infektionen. Abschlussbericht (Stand: 20.Dezember 2012). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2012.
15.
go back to reference ÄKN. Satzung für die Ethikkommission bei der Ärztekammer Niedersachsen. 31.07.1997, zuletzt geändert am. 2006. ÄKN. Satzung für die Ethikkommission bei der Ärztekammer Niedersachsen. 31.07.1997, zuletzt geändert am. 2006.
16.
go back to reference Deshpande KS, Hatem C, Ulrich HL, Currie BP, Aldrich TK, Bryan-Brown CW, et al. The incidence of infectious complications of central venous catheters at the subclavian, internal jugular, and femoral sites in an intensive care unit population. Crit Care Med. 2005;33(1):13–20.CrossRefPubMed Deshpande KS, Hatem C, Ulrich HL, Currie BP, Aldrich TK, Bryan-Brown CW, et al. The incidence of infectious complications of central venous catheters at the subclavian, internal jugular, and femoral sites in an intensive care unit population. Crit Care Med. 2005;33(1):13–20.CrossRefPubMed
17.
go back to reference Darouiche RO. Prevention of infections associated with vascular catheters. Int J Artif Organs. 2008;31(9):810–9.PubMed Darouiche RO. Prevention of infections associated with vascular catheters. Int J Artif Organs. 2008;31(9):810–9.PubMed
18.
go back to reference Wheeler DS, Giaccone MJ, Hutchinson N, Haygood M, Bondurant P, Demmel K, et al. A hospital-wide quality-improvement collaborative to reduce catheter-associated bloodstream infections. Pediatrics. 2011;128(4):e995–1007.CrossRefPubMed Wheeler DS, Giaccone MJ, Hutchinson N, Haygood M, Bondurant P, Demmel K, et al. A hospital-wide quality-improvement collaborative to reduce catheter-associated bloodstream infections. Pediatrics. 2011;128(4):e995–1007.CrossRefPubMed
19.
go back to reference Galpern D, Guerrero A, Tu A, Fahoum B, Wise L. Effectiveness of a central line bundle campaign on line-associated infections in the intensive care unit. Surgery. 2008;144(4):492–5.CrossRefPubMed Galpern D, Guerrero A, Tu A, Fahoum B, Wise L. Effectiveness of a central line bundle campaign on line-associated infections in the intensive care unit. Surgery. 2008;144(4):492–5.CrossRefPubMed
20.
go back to reference WHO. A guide to the implementation of the WHO multimodal hand hygiene improvement strategy. In: Guide to implementation. Genf: World Health Organization; 2009. WHO. A guide to the implementation of the WHO multimodal hand hygiene improvement strategy. In: Guide to implementation. Genf: World Health Organization; 2009.
21.
go back to reference AWMF. Händedesinfektion und Händehygiene. Düsseldorf: Arbeitskreis Krankenhaus- & Praxishygiene der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF); 2008. AWMF. Händedesinfektion und Händehygiene. Düsseldorf: Arbeitskreis Krankenhaus- & Praxishygiene der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF); 2008.
22.
go back to reference O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, et al. Guidelines for the prevention of intravascular catheter-related infections. Atlanta, GA: Centers for Disease Control and Prevention; 2011. O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, et al. Guidelines for the prevention of intravascular catheter-related infections. Atlanta, GA: Centers for Disease Control and Prevention; 2011.
23.
go back to reference DGHO. ZVK Infektionen: Leitlinie. In: Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen. Berlin: Deutsche Gesellschaft für Hämatologie und Onkologie; 2010. DGHO. ZVK Infektionen: Leitlinie. In: Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen. Berlin: Deutsche Gesellschaft für Hämatologie und Onkologie; 2010.
24.
go back to reference KRINKO. Anforderungen an die Hygiene bei Punktionen und Injektionen. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI). Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz. 2011;54(9/10):1135–44. KRINKO. Anforderungen an die Hygiene bei Punktionen und Injektionen. Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI). Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz. 2011;54(9/10):1135–44.
25.
go back to reference AQUA. NEO – Neonatologie. Qualitätsindikatoren. Bundesauswertung zum Erfassungsjahr 2012. Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013. AQUA. NEO – Neonatologie. Qualitätsindikatoren. Bundesauswertung zum Erfassungsjahr 2012. Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013.
26.
go back to reference AQUA. Länderauswertung mit Geodarstellung für veröffentlichungspflichtige Indikatoren (Stand: 04. April 2013). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013. AQUA. Länderauswertung mit Geodarstellung für veröffentlichungspflichtige Indikatoren (Stand: 04. April 2013). Göttingen: AQUA – Institut für angewandte Qualitätsförderung und Forschung im Gesundheitswesen; 2013.
27.
go back to reference AQUA. German Hospital Quality Report 2012. Göttingen: AQUA – Institute for Applied Quality Improvement and Research in Health Care GmbH; 2014. AQUA. German Hospital Quality Report 2012. Göttingen: AQUA – Institute for Applied Quality Improvement and Research in Health Care GmbH; 2014.
28.
go back to reference Ludt S, Urban E, Eckardt J, Wache S, Broge B, Kaufmann-Kolle P, et al. Evaluating the quality of colorectal cancer care across the interface of healthcare sectors. PLoS One. 2013;8(5):e60947.CrossRefPubMedPubMedCentral Ludt S, Urban E, Eckardt J, Wache S, Broge B, Kaufmann-Kolle P, et al. Evaluating the quality of colorectal cancer care across the interface of healthcare sectors. PLoS One. 2013;8(5):e60947.CrossRefPubMedPubMedCentral
29.
go back to reference Uphoff EP, Wennekes L, Punt CJ, Grol RP, Wollersheim HC, Hermens RP, et al. Development of generic quality indicators for patient-centered cancer care by using a RAND modified Delphi method. Cancer Nurs. 2012;35(1):29–37.CrossRefPubMed Uphoff EP, Wennekes L, Punt CJ, Grol RP, Wollersheim HC, Hermens RP, et al. Development of generic quality indicators for patient-centered cancer care by using a RAND modified Delphi method. Cancer Nurs. 2012;35(1):29–37.CrossRefPubMed
30.
go back to reference Pena A, Virk SS, Shewchuk RM, Allison JJ, Williams OD, Kiefe CI. Validity versus feasibility for quality of care indicators: expert panel results from the MI-Plus study. Int J Qual Health Care. 2010;22(3):201–9.CrossRefPubMedPubMedCentral Pena A, Virk SS, Shewchuk RM, Allison JJ, Williams OD, Kiefe CI. Validity versus feasibility for quality of care indicators: expert panel results from the MI-Plus study. Int J Qual Health Care. 2010;22(3):201–9.CrossRefPubMedPubMedCentral
31.
go back to reference Wollersheim H, Hermens R, Hulscher M, Braspenning J, Ouwens M, Schouten J, et al. Clinical indicators: development and applications. Neth J Med. 2007;65(1):15–22.PubMed Wollersheim H, Hermens R, Hulscher M, Braspenning J, Ouwens M, Schouten J, et al. Clinical indicators: development and applications. Neth J Med. 2007;65(1):15–22.PubMed
32.
33.
go back to reference Elwyn G, Buetow S, Hibbard J, Wensing M. Measuring quality through performance. Respecting the subjective: quality measurement from the patient’s perspective. BMJ. 2007;335(7628):1021–2.CrossRefPubMedPubMedCentral Elwyn G, Buetow S, Hibbard J, Wensing M. Measuring quality through performance. Respecting the subjective: quality measurement from the patient’s perspective. BMJ. 2007;335(7628):1021–2.CrossRefPubMedPubMedCentral
34.
go back to reference Szecsenyi J, Broge B, Eckhardt J, Heller G, Kaufmann-Kolle P, Wensing M. Tearing down walls: opening the border between hospital and ambulatory care for quality improvement in Germany. Int J Qual Health Care. 2012;24(2):101–4.CrossRefPubMedPubMedCentral Szecsenyi J, Broge B, Eckhardt J, Heller G, Kaufmann-Kolle P, Wensing M. Tearing down walls: opening the border between hospital and ambulatory care for quality improvement in Germany. Int J Qual Health Care. 2012;24(2):101–4.CrossRefPubMedPubMedCentral
35.
go back to reference Campbell SM, Braspenning J, Hutchinson A, Marshall M. Research methods used in developing and applying quality indicators in primary care. Qual Saf Health Care. 2002;11(4):358–64.CrossRefPubMedPubMedCentral Campbell SM, Braspenning J, Hutchinson A, Marshall M. Research methods used in developing and applying quality indicators in primary care. Qual Saf Health Care. 2002;11(4):358–64.CrossRefPubMedPubMedCentral
36.
go back to reference Campbell PG, Malone J, Yadla S, Chitale R, Nasser R, Maltenfort MG, et al. Comparison of ICD-9-based, retrospective, and prospective assessments of perioperative complications: Assessment of accuracy in reporting - Clinical article. J Neurosurg Spine. 2011;14(1):16–22.CrossRefPubMed Campbell PG, Malone J, Yadla S, Chitale R, Nasser R, Maltenfort MG, et al. Comparison of ICD-9-based, retrospective, and prospective assessments of perioperative complications: Assessment of accuracy in reporting - Clinical article. J Neurosurg Spine. 2011;14(1):16–22.CrossRefPubMed
37.
go back to reference AMA. Measure Testing Protocol for Physician Consortium for Performance Improvement (PCPI) performance measures. American Medical Association; 2010. AMA. Measure Testing Protocol for Physician Consortium for Performance Improvement (PCPI) performance measures. American Medical Association; 2010.
38.
go back to reference Rubin HR, Pronovost P, Diette GB. From a process of care to a measure: the development and testing of a quality indicator. Int J Qual Health Care. 2001;13(6):489–96.CrossRefPubMed Rubin HR, Pronovost P, Diette GB. From a process of care to a measure: the development and testing of a quality indicator. Int J Qual Health Care. 2001;13(6):489–96.CrossRefPubMed
39.
go back to reference Werner RM, Asch DA. The unintended consequences of publicly reporting quality information. JAMA. 2005;293(10):1239–44.CrossRefPubMed Werner RM, Asch DA. The unintended consequences of publicly reporting quality information. JAMA. 2005;293(10):1239–44.CrossRefPubMed
Metadata
Title
Development of quality indicators and data assessment strategies for the prevention of central venous catheter-related bloodstream infections (CRBSI)
Authors
Anke Bramesfeld
Stephanie Wrede
Klaus Richter
Mareike Steen
Björn Broge
Jürgen Pauletzki
Joachim Szecsenyi
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2015
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-015-1200-9

Other articles of this Issue 1/2015

BMC Infectious Diseases 1/2015 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine