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Published in: Trials 1/2017

Open Access 01-12-2017 | Study protocol

Development of an infant feeding core outcome set for childhood obesity interventions: study protocol

Authors: Karen Matvienko-Sikar, Molly Byrne, Colette Kelly, Elaine Toomey, Marita Hennessy, Declan Devane, Caroline Heary, Janas Harrington, Niamh McGrath, Michelle Queally, Patricia M. Kearney

Published in: Trials | Issue 1/2017

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Abstract

Background

Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated in the aetiology of childhood obesity. Infant feeding interventions for childhood obesity are increasingly popular but outcome reporting is inconsistent across trials. Lack of standardisation limits examination of intervention effects and mechanisms of change. The aim of the current project is to develop a core set of infant feeding outcomes for children ≤ 1 year old, to be evaluated in childhood obesity intervention trials.

Methods

This project will use similar methodology to previous core outcome development research. An infant feeding core outcome set (COS) will be developed in four stages: (1) a systematic review of the literature, (2) discussion and clarification of outcomes in a meeting involving multiple stakeholder perspectives, (3) prioritisation of outcomes using the Delphi technique with an expert panel of stakeholders, and (4) achieving consensus on the COS using the nominal group technique (NGT) consensus meeting. An online Delphi survey will be conducted following the NGT meeting to prioritise outcomes identified in the systematic review. An NGT meeting will be conducted with groups of health professionals, non-clinician researchers, and parents of infants ≤ 1 year old, to achieve final consensus on the infant feeding COS.

Discussion

This study aims to develop a core outcome set of infant feeding outcomes for randomised infant feeding studies to prevent childhood obesity. This research will improve examination and syntheses of the outcomes of such studies to prevent and reduce childhood obesity.
Appendix
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Literature
1.
2.
Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9945):766–81.CrossRefPubMedPubMedCentral
3.
Verbeeten KC, Elks CE, Daneman D, Ong KK. Association between childhood obesity and subsequent type 1 diabetes: a systematic review and meta-analysis. Diabet Med. 2011;28(1):10–8.CrossRefPubMed
4.
Llewellyn A, Simmonds M, Owen CG, Woolacott N. Childhood obesity as a predictor of morbidity in adulthood: a systematic review and meta-analysis. Obes Rev. 2016;17(1):56–67.CrossRefPubMed
5.
Sanders RH, Han A, Baker JS, Cobley S. Childhood obesity and its physical and psychological co-morbidities: a systematic review of Australian children and adolescents. Eur J Pediatr. 2015;174(6):715–46.CrossRefPubMed
6.
Simmonds M, Llewellyn A, Owen CG, Woolacott N. Predicting adult obesity from childhood obesity: a systematic review and meta-analysis. Obes Rev. 2016;17(2):95–107.CrossRefPubMed
7.
Thompson ME. Parental feeding and childhood obesity in preschool-age children: recent findings from the literature. Issues Compr Pediatr Nurs. 2010;33(4):205–67.CrossRefPubMed
8.
Skouteris H, McCabe M, Ricciardelli L, et al. Parent-child interactions and obesity prevention: a systematic review of the literature. Early Child Dev Care. 2012;182(2):22.CrossRef
9.
Skinner JD, Carruth BR, Bounds W, Ziegler P, Reidy K. Do food-related experiences in the first 2 years of life predict dietary variety in school-aged children? J Nutr Educ Behav. 2002;34(6):310–5.CrossRefPubMed
10.
11.
Blake-Lamb TL, Locks LM, Perkins ME, Woo Baidal JA, Cheng ER, Taveras EM. Interventions for childhood obesity in the first 1,000 days: a systematic review. Am J Prev Med. 2016;50(6):780–9.CrossRefPubMedPubMedCentral
12.
13.
14.
Kelly LE, Jansson LM, Moulsdale W, et al. A core outcome set for neonatal abstinence syndrome: study protocol for a systematic review, parent interviews and a Delphi survey. Trials. 2016;17:536.CrossRefPubMedPubMedCentral
15.
16.
Moza A, Benstoem C, Autschbach R, et al. A core outcome set for all types of cardiac surgery effectiveness trials: a study protocol for an international eDelphi survey to achieve consensus on what to measure and the subsequent selection of measurement instruments. Trials. 2015;16:545.
17.
Williamson PR, Altman DG, Blazeby JM, et al. Developing core outcome sets for clinical trials: issues to consider. Trials. 2012;13(1):1–8.CrossRef
18.
Williamson PR, Altman DG, Bagley H, et al. The COMET Handbook: version 1.0. Trials. 2017;18 Suppl 3:280.
Metadata
Title
Development of an infant feeding core outcome set for childhood obesity interventions: study protocol
Authors
Karen Matvienko-Sikar
Molly Byrne
Colette Kelly
Elaine Toomey
Marita Hennessy
Declan Devane
Caroline Heary
Janas Harrington
Niamh McGrath
Michelle Queally
Patricia M. Kearney
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Trials / Issue 1/2017
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-017-2180-4

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