Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Breast Cancer Research
Published in: Breast Cancer Research 1/2000

01-03-2000 | Meeting abstract

Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues

Authors: L Elmore, A Akalin, L Gollahon, G Clarke, M Grimes, RT Burks, A Ferreira-Gonzalez, C Garrett, S Holt

Published in: Breast Cancer Research | Special Issue 1/2000

Login to get access

Excerpt

Telomerase is a cellular enzyme that helps to provide genomic stability in tumor cells by maintaining the integrity of telomeres. Telomerase is an RNA-dependent DNA polymerase that contains a protein component (hTERT) and an associated RNA (hTR), which is used as a template for telomere repeat addition. Telomerase activity, while not detectable in most normal human somatic cells, is associated with approximately 85% of malignant human cancers overall, including over 90% of breast cancers. …
Metadata
Title
Development of a high throughput, molecular diagnostic assay for predicting telomerase activity in breast cancer cell lines and tissues
Authors
L Elmore
A Akalin
L Gollahon
G Clarke
M Grimes
RT Burks
A Ferreira-Gonzalez
C Garrett
S Holt
Publication date
01-03-2000
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2000
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr120

Other articles of this Special Issue 1/2000

Breast Cancer Research 1/2000 Go to the issue

Oral presentation

Tissue microarrays for high-throughput profiling in molecular oncology

Meeting abstract

Estrogen-dependent c-jun upregulation may control cyclin D1 expression

Oral presentation

Two molecular cytogenetic views of breast cancer

Meeting abstract

Genetic variants of CYP19 (aromatase) and breast cancer risk

Meeting abstract

The involvement of the MAPK signalling pathway in the adaptation of MCF-7 cells to long-term oestrogen deprivation

Oral presentation

p53 action in apoptosis and senescence
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Image Credits