Published in:
Open Access
01-07-2012 | Poster presentation
Developing juvenile localized scleroderma (jLS) consensus treatment regimens for comparative effectiveness studies
Authors:
Suzanne C Li, Robert C Fuhlbrigge, Fatma Dedeoglu, Polly J Ferguson, Gloria C Higgins, Sandy D Hong, Heidi Jacobe, Andrew Lasky, Ronald M Laxer, Mimi C Morris, Elena Pope, C Egla Rabinovich, Kathryn S Torok, CARRAnet Investigators
Published in:
Pediatric Rheumatology
|
Special Issue 1/2012
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Excerpt
LS can cause significant morbidity in the growing child, including joint contractures and facial and extremity hemiatrophy. Optimal therapy is not known, and few randomized clinical trials have been carried out. A prior survey of Childhood Arthritis and Rheumatology Research Alliance (CARRA) members identified methotrexate (MTX) and corticosteroids (CS) as the most commonly used medications to treat serious jLS. However, there was no consensus on dose, route of administration, or duration of treatment for these medications. Objective: To develop standardized consensus treatment regimens and disease assessments tools for jLS. …
