Top

Published in:

Open Access 01-12-2016 | Research article

Determinants of seasonal influenza vaccination in pregnant women in Valencia, Spain

Authors: R. Vila-Candel, P. Navarro-Illana, E. Navarro-Illana, E. Castro-Sánchez, Kiri Duke, F. J. Soriano-Vidal, J. Tuells, J. Díez-Domingo

Published in: BMC Public Health | Issue 1/2016

Abstract

Background

In most countries the coverage of seasonal influenza vaccination in pregnant women is low. We investigated the acceptance, reasons for rejection and professional involvement related to vaccine information in pregnant women in Valencia, Spain.

Methods

Observational retrospective study in 200 pregnant women, 100 vaccinated and 100 unvaccinated, were interviewed during the 2014/2015 vaccination campaign. Electronic medical records, immunization registry and telephone interviews were used to determine reasons for vaccination and immunization rejection.

Results

40.5% of pregnant women in the health department were vaccinated. The midwife was identified as source of information for 89% of women. The vaccine was rejected due to low perceptions of risk of influenza infection (23%), lack of information (19%), considering the vaccine as superfluous (16%), close proximity of delivery date (13%) and fear of side effects (12%).

Conclusion

Pregnant women in Spain declined to be vaccinated due to under-estimation of the risk of contracting or being harmed by influenza, and lack of information. Interventions aiming to optimize vaccination coverage should include information addressing the safety and effectiveness of the current vaccine together with improved professional training and motivation.

Yuen CYS, Tarrant M. A Comprehensive Review of Influenza and Influenza Vaccination During Pregnancy. J Perinat Neonatal Nurs. 2014;28:261–70.CrossRefPubMed

Panda B, Stiller R, Panda A. Influenza vaccination during pregnancy and factors for lacking compliance with current CDC guidelines. J Matern Fetal Neonatal Med. 2011;24:402–6. doi:10.3109/14767058.2010.497882.CrossRefPubMed

Yuen CYS, Tarrant M. Determinants of uptake of influenza vaccination among pregnant women - A systematic review. Vaccine. 2014;32:4602–13. doi:10.1016/j.vaccine.2014.06.067.CrossRefPubMed

McNeil SA, Dodds LA, Fell DB, Allen VM, Halperin BA, Steinhoff MC, et al. Effect of respiratory hospitalization during pregnancy on infant outcomes. Am J Obstet Gynecol 2011;204. doi:10.1016/j.ajog.2011.04.031.

Hartert TV, Neuzil KM, Shintani AK, Mitchel EF, Snowden MS, Wood LB, et al. Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza season. Am J Obstet Gynecol. 2003;189:1705–12. doi:10.1016/S0002-9378(03)00857-3.CrossRefPubMed

Munoz FM. Safety of influenza vaccines in pregnant women. Am J Obstet Gynecol 2012;207. doi:10.1016/j.ajog.2012.06.072.

Lu P, Bridges CB, Euler GL, Singleton JA. Influenza vaccination of recommended adult populations, U.S., 1989–2005. Vaccine. 2008;26:1786–93. doi:10.1016/j.vaccine.2008.01.040.CrossRefPubMed

Vilca Yengle LM, Campins Martí M, Cabero Roura L, Rodrigo Pendás JÁ, Martínez Gómez X, Hermosilla Pérez E, et al. Influenza vaccination in pregnant women. Coverage, practices and knowledge among obstetricians. Med Clin (Barc). 2010;134:146–51.CrossRef

Regan AK, Mak DB, Hauck YL, Gibbs R, Tracey L, Effler P V. Trends in seasonal influenza vaccine uptake during pregnancy in Western Australia: Implications for midwives. Women Birth 2016. doi:10.1016/j.wombi.2016.01.009.

10.

Dubé E, Laberge C, Guay M, Bramadat P, Roy R, Bettinger JA. Vaccine hesitancy: An overview. Hum Vaccin Immunother. 2013;9(8):1763–73. doi:10.4161/hv.24657.CrossRefPubMedPubMedCentral

11.

Lester RT, McGeer A, Tomlinson G, Detsky AS. Use of, effectiveness of, and attitudes regarding influenza vaccine among house staff. Infect Control Hosp Epidemiol. 2003;24:839–44. doi:10.1086/502146.CrossRefPubMed

12.

Ofstead CL, Tucker SJ, Beebe TJ, Poland GA. Influenza vaccination among registered nurses: information receipt, knowledge, and decision-making at an institution with a multifaceted educational program. Infect Control Hosp Epidemiol. 2008;29:99–106. doi:10.1086/526431.CrossRefPubMed

13.

Yaqub O, Castle-Clarke S, Sevdalis N, Chataway J. Attitudes to vaccination: A critical review. Soc Sci Med. 2014;112:1–11. doi:10.1016/j.socscimed.2014.04.018.CrossRefPubMed

14.

Perlin JB, Septimus EJ, Cormier SB, Moody JA, Hickok JD, Bracken RM. Developing a program to increase seasonal influenza vaccination of healthcare workers: lessons from a system of community hospitals. J Healthc Qual. 2013;35:5–15. doi:10.1111/jhq.12005.CrossRefPubMed

15.

Henninger M, Naleway A, Crane B, Donahue J, Irving S. Predictors of seasonal influenza vaccination during pregnancy. Obstet Gynecol. 2013;121:741–9. doi:10.1097/AOG.0b013e3182878a5a.CrossRefPubMed

16.

Privileggio L, Falchi A, Grisoni M-L, Souty C, Turbelin C, Fonteneau L, et al. Rates of immunization against pandemic and seasonal influenza in persons at high risk of severe influenza illness: a cross-sectional study among patients of the French Sentinelles general practitioners. BMC Public Health. 2013;13:246. doi:10.1186/1471-2458-13-246.CrossRefPubMedPubMedCentral

17.

Pérez-Vilar S, Díez-Domingo J, López-Lacort M, Martínez-Úbeda S, Martinez-Beneito MA. Effectiveness of rotavirus vaccines, licensed but not funded, against rotavirus hospitalizations in the Valencia Region, Spain. BMC Infect Dis. 2015;15:92. doi:10.1186/s12879-015-0811-5.CrossRefPubMedPubMedCentral

18.

Puig-Barberá J, Tormos A, Trushakova S, Sominina A, Pisareva M, Ciblak MA, et al. The Global Influenza Hospital Surveillance Network (GIHSN): A new platform to describe the epidemiology of severe influenza. Influenza Other Respi Viruses. 2015;9:277–86. doi:10.1111/irv.12335.CrossRef

19.

Stockwell MS, Westhoff C, Kharbanda EO, Vargas CY, Camargo S, Vawdrey DK, et al. Influenza vaccine text message reminders for urban, low-income pregnant women: A randomized controlled trial. Am J Public Health 2014;104. doi:10.2105/AJPH.2013.301620.

20.

France EK, Smith-Ray R, McClure D, Hambidge S, Xu S, Yamasaki K, et al. Impact of maternal influenza vaccination during pregnancy on the incidence of acute respiratory illness visits among infants. Arch Pediatr Adolesc Med. 2006;160:1277–83.CrossRefPubMed

21.

Gorman JR, Brewer NT, Wang JB, Chambers CD. Theory-based predictors of influenza vaccination among pregnant women. Vaccine. 2012;31:213–8. doi:10.1016/j.vaccine.2012.10.064.CrossRefPubMed

22.

Ishola DA, Permalloo N, Cordery RJ, Anderson SR. Midwives’ influenza vaccine uptake and their views on vaccination of pregnant women. J Public Health (United Kingdom). 2013;35:570–7. doi:10.1093/pubmed/fds109.CrossRef

23.

Laenen J, Roelants M, Devlieger R, Vandermeulen C. Influenza and pertussis vaccination coverage in pregnant women. Vaccine. 2015;33:2125–31. doi:10.1016/j.vaccine.2015.03.020.CrossRefPubMed

24.

Meharry PM, Colson ER, Grizas AP, Stiller R, Vázquez M. Reasons why women accept or reject the trivalent inactivated influenza vaccine (TIV) during pregnancy. Matern Child Health J. 2013;17:156–64. doi:10.1007/s10995-012-0957-3.CrossRefPubMed

25.

Maher L, Dawson A, Wiley K, Hope K, Torvaldsen S, Lawrence G, et al. Influenza vaccination during pregnancy: a qualitative study of the knowledge, attitudes, beliefs, and practices of general practitioners in Central and South-Western Sydney. BMC Fam Pract. 2014;15:102. doi:10.1186/1471-2296-15-102.CrossRefPubMedPubMedCentral

26.

Torner N, Godoy P, Soldevila N, Toledo D, Rius C, Domínguez A. Primary health care professionals attitudes towards influenza immunzation in Catalonia. Aten Primaria. 2015;48:192–9. doi:10.1016/j.aprim.2014.09.014.CrossRefPubMed

27.

Mak TK, Mangtani P, Leese J, Watson JM, Pfeifer D. Influenza vaccination in pregnancy: current evidence and selected national policies. Lancet Infect Dis. 2008;8:44–52.CrossRefPubMed

28.

Falomir-Pichastor JM, Toscani L, Despointes SH. Determinants of flu vaccination among nurses: The effects of group identification and professional responsibility. Appl Psychol. 2009;58:42–58. doi:10.1111/j.1464-0597.2008.00381.x.CrossRef

29.

Castro-Sánchez E, Chang PWS, Vila-Candel R, Escobedo AA, Holmes AH. Health literacy and infectious diseases: why does it matter? Int J Infect Dis. 2016;43:103–10. doi:10.1016/j.ijid.2015.12.019.CrossRefPubMed

30.

Berkman ND, Sheridan SL, Donahue KE, Halpern DJ, Crotty K. Low health literacy and health outcomes: An updated systematic review. Ann Intern Med. 2011;155:97–107. doi:10.7326/0003-4819-155-2-201107190-00005.CrossRefPubMed

31.

Yudin MH, Salaripour M, Sgro MD. Pregnant women’s knowledge of influenza and the use and safety of the influenza vaccine during pregnancy. J Obstet Gynaecol Can. 2009;31:120–5. doi:10.1016/S1701-2163(16)34095-6.CrossRefPubMed

32.

Tamma PD, Ault KA, Del Rio C, Steinhoff MC, Halsey NA, Omer SB. Safety of influenza vaccination during pregnancy. Am J Obstet Gynecol. 2009;201:547–52.CrossRefPubMed

33.

Kharbanda EO, Vazquez-Benitez G, Lipkind H, Naleway A, Lee G, Nordin JD. Inactivated influenza vaccine during pregnancy and risks for adverse obstetric events. Obstet Gynecol. 2013;122:659–67. doi:10.1097/AOG.0b013e3182a1118a.CrossRefPubMed

34.

Nordin JD, Kharbanda EO, Vazquez Benitez G, Lipkind H, Vellozzi C, DeStefano F. Maternal Influenza Vaccine and Risks for Preterm or Small for Gestational Age Birth. J Pediatr. 2016;164:1051–7.e2. doi:10.1016/j.jpeds.2014.01.037.CrossRef

35.

Christian LM. Optimizing benefits of influenza virus vaccination during pregnancy: Potential behavioral risk factors and interventions. Vaccine. 2014;32:2958–64.CrossRefPubMedPubMedCentral

Title: Determinants of seasonal influenza vaccination in pregnant women in Valencia, Spain
Authors: R. Vila-Candel
P. Navarro-Illana
E. Navarro-Illana
E. Castro-Sánchez
Kiri Duke
F. J. Soriano-Vidal
J. Tuells
J. Díez-Domingo
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Public Health / Issue 1/2016
Electronic ISSN: 1471-2458
DOI: https://doi.org/10.1186/s12889-016-3823-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Determinants of seasonal influenza vaccination in pregnant women in Valencia, Spain

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 1/2016

Adherence to and acceptability of home fortification with vitamins and minerals in children aged 6 to 23 months: a systematic review

Reducing routine vaccination dropout rates: evaluating two interventions in three Kenyan districts, 2014

LInking EDCs in maternal Nutrition to Child health (LINC study) – protocol for prospective cohort to study early life exposure to environmental chemicals and child health

Intention of physicians to implement guidelines for screening and treatment of latent tuberculosis infection in HIV-infected patients in The Netherlands: a mixed-method design

Differences in perceived fairness and health outcomes in two injury compensation systems: a comparative study

The alcohol harm paradox: using a national survey to explore how alcohol may disproportionately impact health in deprived individuals