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Published in: Abdominal Radiology 6/2008

01-11-2008

Detection of upper tract urothelial neoplasms: sensitivity of axial, coronal reformatted, and curved-planar reformatted image-types utilizing 16-row multi-detector CT urography

Authors: Jonathan R. Dillman, Elaine M. Caoili, Richard H. Cohan, James H. Ellis, Isaac R. Francis, Matthew J. Schipper

Published in: Abdominal Radiology | Issue 6/2008

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Abstract

Background

The purpose of our study was to determine the sensitivity of 16-row multi-detector computed tomography urography (CTU) axial, coronal reformatted, and curved-planar reformatted image-types for upper tract urothelial neoplasm detection.

Methods

Twenty-one CTU examinations were identified that contained one or more pathology-proven upper tract urothelial neoplasms during our study period. Two readers independently reviewed 1.25 and 2.5 mm axial, coronal reformatted, and curved-planar reformatted excretory phase CTU images. Each reader then documented the location and appearance of lesions suspicious for upper tract urothelial neoplasm. These results were correlated with relevant endoscopic/surgical procedure notes as well as pathology results.

Results

Reader #1 detected 72%, 63%, 75%, and 72% of the known 32 upper tract urothelial neoplasms using 1.25 mm axial, 2.5 mm axial, coronal reformatted, and curved-planar reformatted image-types, respectively. Reader #2 detected 72% of the known neoplasms using each of the four image-types. No significant difference in sensitivity between image-types was identified. After combining the results for all four image-types, readers #1 and #2 had overall sensitivities of 94% and 91%.

Conclusions

Axial, coronal reformatted, and curved-planar reformatted image-types have similar sensitivities for the detection of upper tract urothelial neoplasm in 16-row multi-detector CTU. Reviewing multiple image-types increases the sensitivity of urothelial lesion detection.
Literature
1.
go back to reference Murakami S, Igarashi T, Hara S, Shimazaki J (1990) Strategies for asymptomatic microscopic hematuria: a prospective study of 1034 patients. J Urol 144:99–101PubMed Murakami S, Igarashi T, Hara S, Shimazaki J (1990) Strategies for asymptomatic microscopic hematuria: a prospective study of 1034 patients. J Urol 144:99–101PubMed
2.
go back to reference Sultana SR, Goodman CM, Byrne DJ, Baxby K (1996) Microscopic haematuria: urological investigation using a standard protocol. Br J Urol 78:691–696PubMed Sultana SR, Goodman CM, Byrne DJ, Baxby K (1996) Microscopic haematuria: urological investigation using a standard protocol. Br J Urol 78:691–696PubMed
3.
go back to reference Khadra MH, Pickard RS, Charlton M, Powell PH, Neal DE (2000) A prospective analysis of 1930 patients with hematuria to evaluate current diagnostic practice. J Urol 163:524–527PubMedCrossRef Khadra MH, Pickard RS, Charlton M, Powell PH, Neal DE (2000) A prospective analysis of 1930 patients with hematuria to evaluate current diagnostic practice. J Urol 163:524–527PubMedCrossRef
4.
go back to reference Urban BA, Buckley J, Soyer P, Scherrer A, Fishman EK (1997) CT appearance of transitional cell carcinoma of the renal pelvis: part 1. Early stage disease. AJR 169:157–161PubMed Urban BA, Buckley J, Soyer P, Scherrer A, Fishman EK (1997) CT appearance of transitional cell carcinoma of the renal pelvis: part 1. Early stage disease. AJR 169:157–161PubMed
5.
go back to reference Caoili EM, Cohan RH, Inampudi P, et al. (2005) MDCT urography of upper tract urothelial neoplasms. AJR 184:1873–1881PubMed Caoili EM, Cohan RH, Inampudi P, et al. (2005) MDCT urography of upper tract urothelial neoplasms. AJR 184:1873–1881PubMed
6.
go back to reference Tsili AC, Efremidis SC, Kalef-Ezra J, et al. (2007) Multi-detector row CT urography on a 16-row CT scanner in the evaluation of urothelial tumors. Eur Radiol 17:1046–1054PubMedCrossRef Tsili AC, Efremidis SC, Kalef-Ezra J, et al. (2007) Multi-detector row CT urography on a 16-row CT scanner in the evaluation of urothelial tumors. Eur Radiol 17:1046–1054PubMedCrossRef
7.
go back to reference Lang EK, Thomas R, Davis R, et al. (2004) Multiphasic helical computerized tomography for the assessment of microscopic hematuria: a prospective study. J Urol 171:237–243PubMedCrossRef Lang EK, Thomas R, Davis R, et al. (2004) Multiphasic helical computerized tomography for the assessment of microscopic hematuria: a prospective study. J Urol 171:237–243PubMedCrossRef
8.
go back to reference Leder RA, Dunnick NR (1990) Transitional cell carcinoma of the pelvicalices and ureter. AJR 155:713–722PubMed Leder RA, Dunnick NR (1990) Transitional cell carcinoma of the pelvicalices and ureter. AJR 155:713–722PubMed
9.
go back to reference Baron RL, McClennan BL, Lee JK, Lawson TL (1982) Computed tomography of transitional-cell carcinoma of the renal pelvis and ureter. Radiology 144:125–130PubMed Baron RL, McClennan BL, Lee JK, Lawson TL (1982) Computed tomography of transitional-cell carcinoma of the renal pelvis and ureter. Radiology 144:125–130PubMed
10.
go back to reference McCoy JG, Honda H, Reznicek M, Williams RD (1991) Computerized tomography for detection and staging of localized and pathologically defined upper tract urothelial tumors. J Urol 146:1500–1503PubMed McCoy JG, Honda H, Reznicek M, Williams RD (1991) Computerized tomography for detection and staging of localized and pathologically defined upper tract urothelial tumors. J Urol 146:1500–1503PubMed
11.
go back to reference Scolieri MJ, Paik ML, Brown SL, Resnick MI (2000) Limitations of computed tomography in the preoperative staging of upper tract urothelial carcinoma. Urology 56:930–934PubMedCrossRef Scolieri MJ, Paik ML, Brown SL, Resnick MI (2000) Limitations of computed tomography in the preoperative staging of upper tract urothelial carcinoma. Urology 56:930–934PubMedCrossRef
12.
go back to reference Chow LC, Kwan SW, Olcott EW, Sommer G (2007) Split-bolus MDCT urography with synchronous nephrographic and excretory phase enhancement. AJR 189:314–322PubMedCrossRef Chow LC, Kwan SW, Olcott EW, Sommer G (2007) Split-bolus MDCT urography with synchronous nephrographic and excretory phase enhancement. AJR 189:314–322PubMedCrossRef
13.
go back to reference Nawfel RD, Judy PF, Schleipman AR, Silverman SG (2004) Patient radiation dose at CT urography and conventional urography. Radiology 232:126–132PubMedCrossRef Nawfel RD, Judy PF, Schleipman AR, Silverman SG (2004) Patient radiation dose at CT urography and conventional urography. Radiology 232:126–132PubMedCrossRef
14.
go back to reference Perlman ES, Rosenfield AT, Wexler JS, Glickman MG (1996) CT urography in the evaluation of urinary tract disease. J Comput Assist Tomogr 20:620–626PubMedCrossRef Perlman ES, Rosenfield AT, Wexler JS, Glickman MG (1996) CT urography in the evaluation of urinary tract disease. J Comput Assist Tomogr 20:620–626PubMedCrossRef
15.
go back to reference McNicholas MM, Raptopoulos VD, Schwartz RK, et al. (1998) Excretory phase CT urography for opacification of the urinary collecting system. AJR 170:1261–1267PubMed McNicholas MM, Raptopoulos VD, Schwartz RK, et al. (1998) Excretory phase CT urography for opacification of the urinary collecting system. AJR 170:1261–1267PubMed
16.
go back to reference Raptopoulos V, McNamara A (2005). Improved pelvicalyceal visualization with multidetector computed tomography urography; comparison with helical tomography. Eur Radiol 15:1834–1840PubMedCrossRef Raptopoulos V, McNamara A (2005). Improved pelvicalyceal visualization with multidetector computed tomography urography; comparison with helical tomography. Eur Radiol 15:1834–1840PubMedCrossRef
Metadata
Title
Detection of upper tract urothelial neoplasms: sensitivity of axial, coronal reformatted, and curved-planar reformatted image-types utilizing 16-row multi-detector CT urography
Authors
Jonathan R. Dillman
Elaine M. Caoili
Richard H. Cohan
James H. Ellis
Isaac R. Francis
Matthew J. Schipper
Publication date
01-11-2008
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 6/2008
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-008-9360-3

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