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01-12-2018 | Short Communication

Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil

Authors: P. O. Figueiredo, A. T. S. Silva, J. S. Oliveira, P. E. Marinho, F. T. Rocha, G. P. Domingos, P. C. P. Poblete, L. B. S. Oliveira, D. C. Duarte, C. A. Bonjardim, J. S. Abrahão, E G. Kroon, B. P. Drumond, D. B. Oliveira, G. S. Trindade

Published in: EcoHealth | Issue 4/2018

Abstract

At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population.

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Title: Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil
Authors: P. O. Figueiredo
A. T. S. Silva
J. S. Oliveira
P. E. Marinho
F. T. Rocha
G. P. Domingos
P. C. P. Poblete
L. B. S. Oliveira
D. C. Duarte
C. A. Bonjardim
J. S. Abrahão
E G. Kroon
B. P. Drumond
D. B. Oliveira
G. S. Trindade
Publication date: 01-12-2018
Publisher: Springer US
Published in: EcoHealth / Issue 4/2018
Print ISSN: 1612-9202
Electronic ISSN: 1612-9210
DOI: https://doi.org/10.1007/s10393-018-1364-z

At a glance: The STEP trials

Springer Medicine

Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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