Skip to main content
Top
Published in: Molecular Imaging and Biology 5/2008

01-09-2008 | Rapid Communication

Design and Fabrication of Phantoms Using Stereolithography for Small-Animal Imaging Systems

Authors: Mi-Ae Park, Robert E. Zimmerman, Andrew Taberner, Michael W. Kaye, Stephen C. Moore

Published in: Molecular Imaging and Biology | Issue 5/2008

Login to get access

Abstract

Purpose

We have investigated a new technology for fabricating phantoms with fine details for use in small-animal imaging.

Procedures

We used a high-resolution, 3-D stereolithography (SL) system to produce performance-evaluation phantoms such as cold-rod Derenzo, hot-channel Derenzo, and Defrise phantoms. SL performance was estimated by measuring the dimensions of many structures using a microscope. We also evaluated the degree of water absorption by two different SL resins, Somos® 11120 and Accura® 40, after curing.

Results

The average bias and precision of the cold-rod structures over the size range 0.5 to 1.0 mm, were −0.4% and 1.74%, respectively. The water absorption study showed that Somos® 11120 is a more suitable material for nuclear medicine applications.

Conclusion

We have demonstrated that SL is a robust and accurate method for fabrication of phantoms for small-animal imaging systems.
Literature
1.
go back to reference Vastenhouw B, Beekman F (2007) Submillimeter total-body murine imaging with U-SPECT-I. J Nucl Med 48(3):487–493PubMed Vastenhouw B, Beekman F (2007) Submillimeter total-body murine imaging with U-SPECT-I. J Nucl Med 48(3):487–493PubMed
2.
go back to reference Stickel JR, Qi J, Cherry SR (2006) Fabrication and characterization of a 0.5-mm Lutetium Oxyorthosilicate detector array for high-resolution PET applications. J Nucl Med 48(1):115–121 Stickel JR, Qi J, Cherry SR (2006) Fabrication and characterization of a 0.5-mm Lutetium Oxyorthosilicate detector array for high-resolution PET applications. J Nucl Med 48(1):115–121
4.
go back to reference Moore SC, Zimmerman RE, Mellen R, Lim CB (2003) Modification of a Triple-Detector SPECT System for Small-Animal Imaging. IEEE Medical Imaging Conference, Portland, October Moore SC, Zimmerman RE, Mellen R, Lim CB (2003) Modification of a Triple-Detector SPECT System for Small-Animal Imaging. IEEE Medical Imaging Conference, Portland, October
5.
go back to reference Ashley S (1991) Rapid prototyping systems. Mech Eng 113(4):34–43 Ashley S (1991) Rapid prototyping systems. Mech Eng 113(4):34–43
6.
go back to reference Renaudin CP, Barbier B, Roriz R et al (1994) Coronary-arteries—new design for 3-dimensinal arterial phantoms. Radiology 190:579–582PubMed Renaudin CP, Barbier B, Roriz R et al (1994) Coronary-arteries—new design for 3-dimensinal arterial phantoms. Radiology 190:579–582PubMed
7.
go back to reference Anderl H, Nedden DZ, Muhlbauer W et al (1994) CT-guided stereolithography as a new tool in craniofacial surgery. Br J Plast Surg 47(1):60–64PubMedCrossRef Anderl H, Nedden DZ, Muhlbauer W et al (1994) CT-guided stereolithography as a new tool in craniofacial surgery. Br J Plast Surg 47(1):60–64PubMedCrossRef
8.
go back to reference Liu QB, Leu MC, Schmitt SM (2006) Rapid prototyping in dentistry: technology and application. Int J Adv Manuf Tech 29:317–335CrossRef Liu QB, Leu MC, Schmitt SM (2006) Rapid prototyping in dentistry: technology and application. Int J Adv Manuf Tech 29:317–335CrossRef
9.
go back to reference Arcaute K, Mann KB, Wicker RB (2006) Stereolithography of three-dimensional bioactive poly (Rthylene Glycol) constructs with encapsulated cells. Ann Biomed Eng 34(9):1429–1441PubMedCrossRef Arcaute K, Mann KB, Wicker RB (2006) Stereolithography of three-dimensional bioactive poly (Rthylene Glycol) constructs with encapsulated cells. Ann Biomed Eng 34(9):1429–1441PubMedCrossRef
10.
go back to reference Schicho K, Figl M et al (2006) Accuracy of treatment planning based on stereolithography in computer assisted surgery. Med Phys 33(9):3408–3417PubMedCrossRef Schicho K, Figl M et al (2006) Accuracy of treatment planning based on stereolithography in computer assisted surgery. Med Phys 33(9):3408–3417PubMedCrossRef
11.
go back to reference Budinger TF, Derenzo SE, Gullberg GT, Greenberg WL, Huesman RH (1977) Emission computer assisted tomography with single-photon and positron annihilation photon emitters. J Comput Assist Tomogr 1:131–145PubMedCrossRef Budinger TF, Derenzo SE, Gullberg GT, Greenberg WL, Huesman RH (1977) Emission computer assisted tomography with single-photon and positron annihilation photon emitters. J Comput Assist Tomogr 1:131–145PubMedCrossRef
12.
go back to reference Zeng GL, Gullberg GT (1990) A study of reconstruction artifacts in cone beam tomography using iterative EM algorithms. IEEE Trans Nucl Sci 37:759–767CrossRef Zeng GL, Gullberg GT (1990) A study of reconstruction artifacts in cone beam tomography using iterative EM algorithms. IEEE Trans Nucl Sci 37:759–767CrossRef
13.
go back to reference Park MA, Zimmerman RE, Vannah JT, Moore SC (2007) Design and fabrication of small phantoms using stereolithography. IEEE Nucl Sci Symp Med Imag Conf Proc (CD-ROM) Park MA, Zimmerman RE, Vannah JT, Moore SC (2007) Design and fabrication of small phantoms using stereolithography. IEEE Nucl Sci Symp Med Imag Conf Proc (CD-ROM)
Metadata
Title
Design and Fabrication of Phantoms Using Stereolithography for Small-Animal Imaging Systems
Authors
Mi-Ae Park
Robert E. Zimmerman
Andrew Taberner
Michael W. Kaye
Stephen C. Moore
Publication date
01-09-2008
Publisher
Springer-Verlag
Published in
Molecular Imaging and Biology / Issue 5/2008
Print ISSN: 1536-1632
Electronic ISSN: 1860-2002
DOI
https://doi.org/10.1007/s11307-008-0150-7

Other articles of this Issue 5/2008

Molecular Imaging and Biology 5/2008 Go to the issue