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Social Psychiatry and Psychiatric Epidemiology

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Open Access 01-04-2012 | Original Paper

Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study

Authors: Wen Jie Sun, Lin Xu, Wai Man Chan, Tai Hing Lam, C. Mary Schooling

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 4/2012

Abstract

Objective

To examine dose–response associations between depressive symptoms and suicide and modification effects of sex, age and health status in older Chinese.

Methods

We used the Chinese version of the 15-item Geriatric Depression Scale (GDS) to measure depressive symptoms (GDS score ≥ 8) and Cox regression to examine association with suicide mortality in a population-based cohort of 55,946 individuals, aged 65 years or above, enrolled from July 1998 to December 2000 at one of 18 Elderly Health Centres of Hong Kong Department of Health. The cohort was followed up for suicide mortality till 31 March 2009 (mean follow-up 8.7 years).

Results

Depressive symptoms were associated with suicide in men [hazard ratio (HR) 2.03, 95% confidence interval (CI) 0.96–4.29] and women (HR = 2.36, 95% CI 1.31–4.24) after adjusting for age, education, monthly expenditure, smoking, alcohol drinking, physical activity, body mass index, health status, and self-rated health. There was no threshold for GDS score and suicide in either sex. Age, sex and health status did not modify the association.

Conclusions

Depressive symptoms predict higher suicide risk in older Chinese in a dose–response pattern. These associations were not attenuated by adjustment for health status, suggesting that depressive symptoms in older people are likely to be an independent causal factor for suicide. The GDS score showed no threshold in predicting suicide risk, suggesting that older people with low GDS scores deserve further attention and those with very high scores need urgent intervention.

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Title: Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study
Authors: Wen Jie Sun
Lin Xu
Wai Man Chan
Tai Hing Lam
C. Mary Schooling
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Social Psychiatry and Psychiatric Epidemiology / Issue 4/2012
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI: https://doi.org/10.1007/s00127-011-0362-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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