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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Demonstration of novel innate immune cells in psoriasis

Authors: R Mak, C Hundhausen, E Botti, U Laggner, K Grys, I Tosi, F O Nestle

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

Psoriasis is a common chronic inflammatory skin disorder affecting ~2% of the population worldwide. Both the adaptive and innate immune systems are important in driving the inflammation in genetically susceptible individuals. HLA-Cw6 located within the PSORS1 region on chromosome 6 is the most important psoriasis genetic marker. Correlations of HLA-C expression with different disease incidence and progression are described in the context of HLA-C’s interaction with killer-like immunoglobulin receptors (KIR) expressed on innate immune effector cells; natural killer (NK) and natural killer T (NKT) cells. …
Metadata
Title
Demonstration of novel innate immune cells in psoriasis
Authors
R Mak
C Hundhausen
E Botti
U Laggner
K Grys
I Tosi
F O Nestle
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P18

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Prof. Kevin Dolgin
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Developed by: Springer Medicine
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