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Published in: Archives of Gynecology and Obstetrics 2/2010

01-02-2010 | Case Report

Delayed-interval delivery of an in vitro-fertilized triplet pregnancy with premature rupture of membranes in the second trimester

Authors: Mehmet Ali Yuce, Aysun Aybatlı, Petek Balkanlı Kaplan

Published in: Archives of Gynecology and Obstetrics | Issue 2/2010

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Abstract

Background

The incidence of multiple pregnancies is increasing with the availability of assisted reproductive techniques. Preterm labor and preterm rupture of membranes are major complications in such pregnancies. Preterm delivery of the first fetus is often followed by delivery of the remaining fetuses. However, conservative management in such circumstances might allow for fetal lung maturity in the remaining fetuses.

Case

We present a case of conservative management of an in vitro-fertilized triplet pregnancy with early loss of the leading triplet. A 33-year-old woman in the 21st week of a triplet pregnancy delivered her one of the fetuses, 4 days after the preterm rupture of membranes. To save the surviving fetuses, ligation of the umbilical cord at the cervical level was performed. Patient received antibiotics, tocolytics and corticosteroids after then. The second and the third fetuses were successfully delivered by cesarean section in the 28th week of pregnancy, 43 days after the first fetus was born.

Conclusion

We can improve the life expectancy of the retained fetuses by conservative management using tocolytics, antenatal steroids to stimulate lung maturation and antibiotics following the delivery of the first fetus.
Literature
1.
go back to reference Platt J, Rosa C (1999) Delayed interval delivery in multiple gestations. Obstet Gynecol Surv 54(5):343–348CrossRefPubMed Platt J, Rosa C (1999) Delayed interval delivery in multiple gestations. Obstet Gynecol Surv 54(5):343–348CrossRefPubMed
2.
go back to reference MacLennan AH (1994) Multiple gestation: clinical characteristics and management. In: Creasy RK, Resnik R (eds) Maternal fetal medicine: principles and practice, 3rd edn. WB Saunders, Philadelphia, pp 589–599 MacLennan AH (1994) Multiple gestation: clinical characteristics and management. In: Creasy RK, Resnik R (eds) Maternal fetal medicine: principles and practice, 3rd edn. WB Saunders, Philadelphia, pp 589–599
3.
go back to reference Lipitz S, Reichman B, Paret G et al (1989) The improving outcome of triplet pregnancies. Am J Obstet Gynecol 161:1279PubMed Lipitz S, Reichman B, Paret G et al (1989) The improving outcome of triplet pregnancies. Am J Obstet Gynecol 161:1279PubMed
4.
go back to reference Fanaroff AA, Wright LL, Stevenson DK et al (1995) Very-low-birth-weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, May 1991 through December 1992. Am J Obstet Gynecol 173:1423–1431 Fanaroff AA, Wright LL, Stevenson DK et al (1995) Very-low-birth-weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, May 1991 through December 1992. Am J Obstet Gynecol 173:1423–1431
5.
go back to reference Zhang J, Hamilton B, Martin J, Trumble A (2004) Delayed interval delivery and infant survival: a population-based study. Am J Obstet Gynecol 191:470–476CrossRefPubMed Zhang J, Hamilton B, Martin J, Trumble A (2004) Delayed interval delivery and infant survival: a population-based study. Am J Obstet Gynecol 191:470–476CrossRefPubMed
6.
go back to reference Farkouh LJ, Sabin ED, Heyborne KD, Lindsay G, Porreco RP (2000) Delayed-interval delivery: extended series from a single maternal–fetal medicine practice. Am J Obstet Gynecol 183:1499–1503CrossRefPubMed Farkouh LJ, Sabin ED, Heyborne KD, Lindsay G, Porreco RP (2000) Delayed-interval delivery: extended series from a single maternal–fetal medicine practice. Am J Obstet Gynecol 183:1499–1503CrossRefPubMed
7.
go back to reference Arias F (1994) Delayed delivery of multifetal pregnancies with premature rupture of membranes in the second trimester. Am J Obstet Gynecol 170:1233–1237PubMed Arias F (1994) Delayed delivery of multifetal pregnancies with premature rupture of membranes in the second trimester. Am J Obstet Gynecol 170:1233–1237PubMed
8.
go back to reference von Dadelszen P (2008) Review: multiple doses of antenatal corticosteroids prevent preterm neonatal respiratory disease more than a single dose. Evid Based Med 13(3):81CrossRef von Dadelszen P (2008) Review: multiple doses of antenatal corticosteroids prevent preterm neonatal respiratory disease more than a single dose. Evid Based Med 13(3):81CrossRef
9.
go back to reference Kalchbrenner MA, Weisenborn EJ, Chyu JK, Kaufman HK, Losure TA (1998) Delayed delivery of multiple gestations: maternal and neonatal outcomes. Am J Obstet Gynecol 179:1145–1149CrossRefPubMed Kalchbrenner MA, Weisenborn EJ, Chyu JK, Kaufman HK, Losure TA (1998) Delayed delivery of multiple gestations: maternal and neonatal outcomes. Am J Obstet Gynecol 179:1145–1149CrossRefPubMed
10.
go back to reference van Doorn HC, Wezel-Meijler G, van Geijn HP, Dekker GA (1999) Delayed interval delivery in multiple pregnancies: is optimism justified? Acta Obstet Gynecol Scand 78:710–715CrossRefPubMed van Doorn HC, Wezel-Meijler G, van Geijn HP, Dekker GA (1999) Delayed interval delivery in multiple pregnancies: is optimism justified? Acta Obstet Gynecol Scand 78:710–715CrossRefPubMed
11.
go back to reference Hoffman M, Walker S, Pollock M, Sciscione A (2000) Delayed interval delivery in multifetal pregnancies in the second trimester: maternal and neonatal outcomes. Obstet Gynecol 95:76SCrossRef Hoffman M, Walker S, Pollock M, Sciscione A (2000) Delayed interval delivery in multifetal pregnancies in the second trimester: maternal and neonatal outcomes. Obstet Gynecol 95:76SCrossRef
12.
go back to reference Van der Straeten FMA, De ketelaere K, Temmerman M (2001) Delayed interval delivery in multiple pregnancies. Eur J Obstet Gynecol Reprod Biol 99:85–89CrossRefPubMed Van der Straeten FMA, De ketelaere K, Temmerman M (2001) Delayed interval delivery in multiple pregnancies. Eur J Obstet Gynecol Reprod Biol 99:85–89CrossRefPubMed
13.
go back to reference Hamersley SL, Coleman SK, Bergauer NK, Bartholomew LM, Pinckert TL (2002) Delayed-interval delivery in twin pregnancies. J Reprod Med 47:125–130PubMed Hamersley SL, Coleman SK, Bergauer NK, Bartholomew LM, Pinckert TL (2002) Delayed-interval delivery in twin pregnancies. J Reprod Med 47:125–130PubMed
14.
go back to reference Fayad S, Bongain A, Holhfeld P, Janky E, Durand-Reville M, Ejnes L, Schaaps JP, Gillet JY (2003) Delayed delivery of second twin: a multicentre study of 35 cases. Eur J Obstet Gynecol Reprod Biol 109:16–20CrossRefPubMed Fayad S, Bongain A, Holhfeld P, Janky E, Durand-Reville M, Ejnes L, Schaaps JP, Gillet JY (2003) Delayed delivery of second twin: a multicentre study of 35 cases. Eur J Obstet Gynecol Reprod Biol 109:16–20CrossRefPubMed
15.
go back to reference Oyelese Y, Ananth CV, Smulian JC, Vintzileos AM (2005) Delayed interval delivery in twin pregnancies in the United States: impact on perinatal mortality and morbidity. Am J Obstet Gynecol 192:439–444CrossRefPubMed Oyelese Y, Ananth CV, Smulian JC, Vintzileos AM (2005) Delayed interval delivery in twin pregnancies in the United States: impact on perinatal mortality and morbidity. Am J Obstet Gynecol 192:439–444CrossRefPubMed
16.
go back to reference Mordel N, Zejicek G, Benshushan A, Schenker JG, Laufer N, Sadovsky E (1993) Elective suture of uterine cervix in triplets. Am J Perinatol 10:14–16CrossRefPubMed Mordel N, Zejicek G, Benshushan A, Schenker JG, Laufer N, Sadovsky E (1993) Elective suture of uterine cervix in triplets. Am J Perinatol 10:14–16CrossRefPubMed
17.
go back to reference Rust OA, Atlas RO, Jones KJ, Benham BN, Balducci J (2000) A randomized trial of cerclage versus no cerclage among patients with ultrasonographically detected second-trimester preterm dilatation of the internal os. Am J Obstet Gynecol 183:830–835CrossRefPubMed Rust OA, Atlas RO, Jones KJ, Benham BN, Balducci J (2000) A randomized trial of cerclage versus no cerclage among patients with ultrasonographically detected second-trimester preterm dilatation of the internal os. Am J Obstet Gynecol 183:830–835CrossRefPubMed
18.
go back to reference Zhang Jun, Johnson Courtney D, Hoffman Matthew (2003) Cervical cerclage in delayed interval delivery in a multifetal pregnancy a review of seven case series. Eur J Obstet Gynecol Reprod Biol 108:126–130CrossRefPubMed Zhang Jun, Johnson Courtney D, Hoffman Matthew (2003) Cervical cerclage in delayed interval delivery in a multifetal pregnancy a review of seven case series. Eur J Obstet Gynecol Reprod Biol 108:126–130CrossRefPubMed
19.
go back to reference Abboud P, Gallais A, Janky E (1997) Intentional delayed delivery in twin pregnancy: two additional cases and literature review. Eur J Obstet Gynecol Reprod Biol 75(2):139–143CrossRefPubMed Abboud P, Gallais A, Janky E (1997) Intentional delayed delivery in twin pregnancy: two additional cases and literature review. Eur J Obstet Gynecol Reprod Biol 75(2):139–143CrossRefPubMed
20.
go back to reference Antsaklis A, Daskalakis G, Papageorgiou I, Aravantinos D (1996) Conservative treatment after pregnancies: report of three cases and review of the literature. Fetal Diagn Ther 11(5):366–372CrossRefPubMed Antsaklis A, Daskalakis G, Papageorgiou I, Aravantinos D (1996) Conservative treatment after pregnancies: report of three cases and review of the literature. Fetal Diagn Ther 11(5):366–372CrossRefPubMed
21.
go back to reference Daikoku NH, Graham D, Gopal JJ, Frattarrola IG, Rock JA (1993) Delayed birth intervals of immature fraternel triplet in preterm labor: a case report. J Reprod Med 38:734–736PubMed Daikoku NH, Graham D, Gopal JJ, Frattarrola IG, Rock JA (1993) Delayed birth intervals of immature fraternel triplet in preterm labor: a case report. J Reprod Med 38:734–736PubMed
Metadata
Title
Delayed-interval delivery of an in vitro-fertilized triplet pregnancy with premature rupture of membranes in the second trimester
Authors
Mehmet Ali Yuce
Aysun Aybatlı
Petek Balkanlı Kaplan
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 2/2010
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1172-3

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