Skip to main content
Top
Published in: Acta Neurochirurgica 6/2023

28-04-2023 | Degenerative Disease | Technical Note

Biportal endoscopic extraforaminal lumbar interbody fusion using a 3D-printed porous titanium cage with large footprints: technical note and preliminary results

Authors: Ki-Han You, Jae-Yeun Hwang, Seok-Ho Hong, Min-Seok Kang, Sang-Min Park, Hyun-Jin Park

Published in: Acta Neurochirurgica | Issue 6/2023

Login to get access

Abstract

Purpose

The aim of this study was to introduce biportal endoscopic extraforaminal lumbar interbody fusion (BE-EFLIF), which involves insertion of a cage through a more lateral side as compared to the conventional corridor of transforaminal lumbar interbody fusion. We described the advantages and surgical steps of 3D-printed porous titanium cage with large footprints insertion through multi-portal approach, and preliminary results of this technique.

Methods

This retrospective study included 12 consecutive patients who underwent BE-EFLIF for symptomatic single-level lumbar degenerative disease. Clinical outcomes, including a visual analog scale (VAS) for back and leg pain and the Oswestry disability index (ODI), were collected at preoperative months 1 and 3, and 6 months postoperatively. In addition, perioperative data and radiographic parameters were analyzed.

Results

The mean patient age, follow-up period, operation time, and volume of surgical drainage were 68.3 ± 8.4 years, 7.6 ± 2.8 months, 188.3 ± 42.4 min, 92.5 ± 49.6 mL, respectively. There were no transfusion cases. All patients showed significant improvement in VAS and ODI postoperatively, and these were maintained for 6 months after surgery (P < 0.001). The anterior and posterior disc heights significantly increased after surgery (P < 0.001), and the cage was ideally positioned in all patients. There were no incidences of early cage subsidence or other complications.

Conclusions

BE-EFLIF using a 3D-printed porous titanium cage with large footprints is a feasible option for minimally invasive lumbar interbody fusion. This technique is expected to reduce the risk of cage subsidence and improve the fusion rate.
Appendix
Available only for authorised users
Literature
1.
go back to reference Amini DA, Okano I, Oezel L, Zhu J, Chiapparelli E, Shue J, Sama AA, Cammisa FP, Girardi FP, Hughes AP (2021) Evaluation of cage subsidence in standalone lateral lumbar interbody fusion: novel 3D-printed titanium versus polyetheretherketone (PEEK) cage. Eur spine J 30:2377–2384CrossRef Amini DA, Okano I, Oezel L, Zhu J, Chiapparelli E, Shue J, Sama AA, Cammisa FP, Girardi FP, Hughes AP (2021) Evaluation of cage subsidence in standalone lateral lumbar interbody fusion: novel 3D-printed titanium versus polyetheretherketone (PEEK) cage. Eur spine J 30:2377–2384CrossRef
2.
go back to reference Choi JY, Park SM, Kim HJ, Yeom JS (2022) Recent updates on minimally invasive spine surgery: techniques, technologies, and indications. Asian Spine J 16(6):1013–1021CrossRefPubMedPubMedCentral Choi JY, Park SM, Kim HJ, Yeom JS (2022) Recent updates on minimally invasive spine surgery: techniques, technologies, and indications. Asian Spine J 16(6):1013–1021CrossRefPubMedPubMedCentral
3.
go back to reference Foley KT, Holly LT, Schwender JD (2003) Minimally invasive lumbar fusion. Spine (Phila Pa 1976) 28:S26–S35CrossRefPubMed Foley KT, Holly LT, Schwender JD (2003) Minimally invasive lumbar fusion. Spine (Phila Pa 1976) 28:S26–S35CrossRefPubMed
5.
go back to reference Goldstein CL, Macwan K, Sundararajan K, Rampersaud YR (2016) Perioperative outcomes and adverse events of minimally invasive versus open posterior lumbar fusion: meta-analysis and systematic review. J Neurosurg Spine 24:416–427CrossRefPubMed Goldstein CL, Macwan K, Sundararajan K, Rampersaud YR (2016) Perioperative outcomes and adverse events of minimally invasive versus open posterior lumbar fusion: meta-analysis and systematic review. J Neurosurg Spine 24:416–427CrossRefPubMed
6.
go back to reference Harms J, Rolinger H (1982) A one-stager procedure in operative treatment of spondylolistheses: dorsal traction-reposition and anterior fusion (author’s transl). Z Orthop Ihre Grenzgeb 120:343–347CrossRefPubMed Harms J, Rolinger H (1982) A one-stager procedure in operative treatment of spondylolistheses: dorsal traction-reposition and anterior fusion (author’s transl). Z Orthop Ihre Grenzgeb 120:343–347CrossRefPubMed
7.
go back to reference Heo DH, Park CK (2019) Clinical results of percutaneous biportal endoscopic lumbar interbody fusion with application of enhanced recovery after surgery. Neurosurg focus 46:E18CrossRefPubMed Heo DH, Park CK (2019) Clinical results of percutaneous biportal endoscopic lumbar interbody fusion with application of enhanced recovery after surgery. Neurosurg focus 46:E18CrossRefPubMed
8.
go back to reference Horn MRV, Beard R, Wang W, Cunningham BW, Mullinix KP, Allall M, Sama AA, Cammisa FP, Girardi FP, Hughes AP (2021) Comparison of 3D-printed titanium-alloy, standard titanium-alloy, and PEEK interbody spacers in an ovine model. Spine J 21:2097–2103CrossRefPubMed Horn MRV, Beard R, Wang W, Cunningham BW, Mullinix KP, Allall M, Sama AA, Cammisa FP, Girardi FP, Hughes AP (2021) Comparison of 3D-printed titanium-alloy, standard titanium-alloy, and PEEK interbody spacers in an ovine model. Spine J 21:2097–2103CrossRefPubMed
9.
go back to reference Kang MS, You KH, Choi JY, Heo DH, Chung HJ, Park HJ (2021) Minimally invasive transforaminal lumbar interbody fusion using biportal endoscopic techniques versus microscopic tubular technique. Spine J 21:2066–2077CrossRefPubMed Kang MS, You KH, Choi JY, Heo DH, Chung HJ, Park HJ (2021) Minimally invasive transforaminal lumbar interbody fusion using biportal endoscopic techniques versus microscopic tubular technique. Spine J 21:2066–2077CrossRefPubMed
10.
go back to reference KDK L, DHK C, Holmes A (2003) Vertical instability in spondylolisthesis: a traction radiographic assessment technique and the principle of management. Spine (Phila Pa 1976) 28:819–827CrossRef KDK L, DHK C, Holmes A (2003) Vertical instability in spondylolisthesis: a traction radiographic assessment technique and the principle of management. Spine (Phila Pa 1976) 28:819–827CrossRef
11.
go back to reference Kim JE, Yoo HS, Choi DJ, Park EJ, Jee SM (2021) Comparison of minimally invasive versus biportal endoscopic transforaminal lumbar interbody fusion for single-level lumbar disease. Clin Spine Surg 34:E64–E71CrossRefPubMed Kim JE, Yoo HS, Choi DJ, Park EJ, Jee SM (2021) Comparison of minimally invasive versus biportal endoscopic transforaminal lumbar interbody fusion for single-level lumbar disease. Clin Spine Surg 34:E64–E71CrossRefPubMed
12.
13.
go back to reference Laratta JL, Vivace BJ, Lopez-Pena M, Guzon FM, Gonzalez-Cantalpeidra A, Jorge-Mora A, Villar-Liste RM, Pino-Lopez L, Lukyanchuk A, Taghizadeh EA, Pino-Minguez J (2022) 3D-printed titanium cages without bone graft outperform PEEK cages with autograft in an animal model. Spine J 22:1016–1027CrossRefPubMed Laratta JL, Vivace BJ, Lopez-Pena M, Guzon FM, Gonzalez-Cantalpeidra A, Jorge-Mora A, Villar-Liste RM, Pino-Lopez L, Lukyanchuk A, Taghizadeh EA, Pino-Minguez J (2022) 3D-printed titanium cages without bone graft outperform PEEK cages with autograft in an animal model. Spine J 22:1016–1027CrossRefPubMed
14.
go back to reference Lee JYB, Whang PG, Lee JY, Phillips FM, Patel AA (2013) Lumbar spinal stenosis. Instr Course Lect 62:383–396PubMed Lee JYB, Whang PG, Lee JY, Phillips FM, Patel AA (2013) Lumbar spinal stenosis. Instr Course Lect 62:383–396PubMed
15.
go back to reference Li H, Zou X, Laursen M, Egund N, Lind M, Bunger C (2002) The influence of intervertebral disc tissue on anterior spinal interbody fusion: an experimental study on pigs. Eur Spine J 11:476–481CrossRefPubMedPubMedCentral Li H, Zou X, Laursen M, Egund N, Lind M, Bunger C (2002) The influence of intervertebral disc tissue on anterior spinal interbody fusion: an experimental study on pigs. Eur Spine J 11:476–481CrossRefPubMedPubMedCentral
16.
go back to reference Mobbs RJ, Phan K, Malham G, Seex K, Rao PJ (2015) Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF. J Spine Surg 1:2–18PubMedPubMedCentral Mobbs RJ, Phan K, Malham G, Seex K, Rao PJ (2015) Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF. J Spine Surg 1:2–18PubMedPubMedCentral
17.
18.
go back to reference Park MK, Park SA, Son SK, Park WW, Choi SH (2019) Clinical and radiological outcomes of unilateral biportal endoscopic lumbar interbody fusion (ULIF) compared with conventional posterior lumbar interbody fusion (PLIF): 1-year follow-up. Neurosurg Rev 42:753-761 Park MK, Park SA, Son SK, Park WW, Choi SH (2019) Clinical and radiological outcomes of unilateral biportal endoscopic lumbar interbody fusion (ULIF) compared with conventional posterior lumbar interbody fusion (PLIF): 1-year follow-up. Neurosurg Rev 42:753-761
19.
go back to reference Park SJ, Lee CS, Chung SS, Kang SS, Park HJ, Kim SH (2017) The ideal cage position for achieving both indirect neural decompression and segmental angle restoration in lateral lumbar interbody fusion (LLIF). Clin Spine surg 30:E784–E790CrossRefPubMed Park SJ, Lee CS, Chung SS, Kang SS, Park HJ, Kim SH (2017) The ideal cage position for achieving both indirect neural decompression and segmental angle restoration in lateral lumbar interbody fusion (LLIF). Clin Spine surg 30:E784–E790CrossRefPubMed
20.
go back to reference Pimenta L, Turner AWL, Dooley ZA, Parikh RD, Peterson MD (2012) Biomechanics of lateral interbody spacers: going wider for going stiffer. Sci World J 2012:381814CrossRef Pimenta L, Turner AWL, Dooley ZA, Parikh RD, Peterson MD (2012) Biomechanics of lateral interbody spacers: going wider for going stiffer. Sci World J 2012:381814CrossRef
21.
go back to reference Rao PJ, Phan K, Giang G, Maharaj MM, Phan S, Mobbs RJ (2017) Subsidence following anterior lumbar interbody fusion (ALIF): a prospective study. J Spine Surg 3:168–175CrossRefPubMedPubMedCentral Rao PJ, Phan K, Giang G, Maharaj MM, Phan S, Mobbs RJ (2017) Subsidence following anterior lumbar interbody fusion (ALIF): a prospective study. J Spine Surg 3:168–175CrossRefPubMedPubMedCentral
22.
go back to reference Resnick DK, Choudhri TF, Dailey AT, Groff MW, Khoo L, Matz PG, Mummaneni P, Watters WC 3rd, Wang J, Walters BC, Hadley MN, American Association of Neurological Surgeons/Congress of Neurological Surgeons (2005) Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 7: intractable low-back pain without stenosis or spondylolisthesis. J Neurosurg Spine 2:670–672CrossRefPubMed Resnick DK, Choudhri TF, Dailey AT, Groff MW, Khoo L, Matz PG, Mummaneni P, Watters WC 3rd, Wang J, Walters BC, Hadley MN, American Association of Neurological Surgeons/Congress of Neurological Surgeons (2005) Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 7: intractable low-back pain without stenosis or spondylolisthesis. J Neurosurg Spine 2:670–672CrossRefPubMed
23.
go back to reference Rihn JA, Gandhi SD, Sheehan P, Vaccaro AR, Hilibrand AS, Albert TJ, Anderson DG (2014) Disc space preparation in transforaminal lumbar interbody fusion: a comparison of minimally invasive and open approaches. Clin Orthop Relat Res 472:1800–1805CrossRefPubMedPubMedCentral Rihn JA, Gandhi SD, Sheehan P, Vaccaro AR, Hilibrand AS, Albert TJ, Anderson DG (2014) Disc space preparation in transforaminal lumbar interbody fusion: a comparison of minimally invasive and open approaches. Clin Orthop Relat Res 472:1800–1805CrossRefPubMedPubMedCentral
24.
go back to reference Seaman S, Kerezoudis P, Bydon M, Torner JC, Hitchon PW (2017) Titanium vs. polyetheretherketone (PEEK) interbody fusion: meta-analysis and review of the literature. J Clin Neurosci 44:23–29CrossRefPubMed Seaman S, Kerezoudis P, Bydon M, Torner JC, Hitchon PW (2017) Titanium vs. polyetheretherketone (PEEK) interbody fusion: meta-analysis and review of the literature. J Clin Neurosci 44:23–29CrossRefPubMed
25.
go back to reference Teng I, Han J, Phan K, Mobbs R (2017) A meta-analysis comparing ALIF, PLIF, TLIF and LLIF. J Clin Neurosci 44:11–17CrossRefPubMed Teng I, Han J, Phan K, Mobbs R (2017) A meta-analysis comparing ALIF, PLIF, TLIF and LLIF. J Clin Neurosci 44:11–17CrossRefPubMed
27.
go back to reference Zhang X, Wu H, Chen Y, Liu J, Chen J, Zhang T, Zhou Z, Fan S, Dolan P, Adams MA, Zhao F (2021) Importance of the epiphyseal ring in OLIF stand-alone surgery: a biomechanical study on cadaveric spines. Eur Spine J 30:79–87CrossRefPubMed Zhang X, Wu H, Chen Y, Liu J, Chen J, Zhang T, Zhou Z, Fan S, Dolan P, Adams MA, Zhao F (2021) Importance of the epiphyseal ring in OLIF stand-alone surgery: a biomechanical study on cadaveric spines. Eur Spine J 30:79–87CrossRefPubMed
Metadata
Title
Biportal endoscopic extraforaminal lumbar interbody fusion using a 3D-printed porous titanium cage with large footprints: technical note and preliminary results
Authors
Ki-Han You
Jae-Yeun Hwang
Seok-Ho Hong
Min-Seok Kang
Sang-Min Park
Hyun-Jin Park
Publication date
28-04-2023
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 6/2023
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-023-05605-7

Other articles of this Issue 6/2023

Acta Neurochirurgica 6/2023 Go to the issue