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Annals of Vascular Surgery
Published in: Annals of Vascular Surgery 1/2004

01-02-2004 | Case Reports

Deep Venous Thrombosis Caused by Congenital Absence of Inferior Vena Cava, Combined with Hyperhomocysteinemia

Authors: Sang Seob Yun, MD, Ji Il Kim, MD, Kee Hwan Kim, MD, Gi Young Sung, MD, Do Sang Lee, MD, Jeong Soo Kim, MD, In Sung Moon, MD, Keun Woo Lim, MD, Young Bok Koh, MD

Published in: Annals of Vascular Surgery | Issue 1/2004

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Abstract

We present a case of suprarenal and infrarenal absence of the inferior vena cava, combined with hyperhomocysteinemia in a 39-year-old woman who presented with symptoms of deep venous thrombosis. The patient also had a homozygous mutation of C677T methylenetetrahydrofolate reductase. Deep vein thrombosis has a multifactorial etiology involving both genetic and acquired factors. Absence of the inferior vena cava is a rare congenital anomaly, but recently it was confirmed as an important risk factor for the development of deep vein thrombosis, especially in young persons. Hypercoagulability due to hyperhomocysteinemia with a tendency toward venous stasis, mediated by congenital absence of the inferior vena cava is thought to have caused deep vein thrombosis in our patient. To our knowledge, this association has not yet been reported. The clinical features and prognosis of this entity are discussed.
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Metadata
Title
Deep Venous Thrombosis Caused by Congenital Absence of Inferior Vena Cava, Combined with Hyperhomocysteinemia
Authors
Sang Seob Yun, MD
Ji Il Kim, MD
Kee Hwan Kim, MD
Gi Young Sung, MD
Do Sang Lee, MD
Jeong Soo Kim, MD
In Sung Moon, MD
Keun Woo Lim, MD
Young Bok Koh, MD
Publication date
01-02-2004
Publisher
Springer-Verlag
Published in
Annals of Vascular Surgery / Issue 1/2004
Print ISSN: 0890-5096
Electronic ISSN: 1615-5947
DOI
https://doi.org/10.1007/s10016-003-0087-x

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