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Breast Cancer Research
Published in: Breast Cancer Research 1/2010

01-05-2010 | Poster presentation

D133P53, directly transactivated by p53, prevents p53-mediated apoptosis without inhibiting p53-mediated cell cycle arrest

Authors: M Aoubala, F Murray-Zmijewski, M Khoury, S Perrier, K Fernandes, AC Prats, D Lane, JC Bourdon

Published in: Breast Cancer Research | Special Issue 1/2010

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Excerpt

We recently reported that the human p53 gene encodes at least nine different p53 isoforms, two of which (p53β and Δ133p53) can modulate p53 transcriptional activity and apoptosis. In the present study, we aimed to investigate the regulation of Δ133p53 isoform expression and the physiological role of Δ133p53 in modulating p53 activities. …
Metadata
Title
D133P53, directly transactivated by p53, prevents p53-mediated apoptosis without inhibiting p53-mediated cell cycle arrest
Authors
M Aoubala
F Murray-Zmijewski
M Khoury
S Perrier
K Fernandes
AC Prats
D Lane
JC Bourdon
Publication date
01-05-2010
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2010
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr2505

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