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01-08-2019 | Cytostatic Therapy | Case Report - Brain Tumors

Endonasal surgery for suprasellar germ cell tumors: two cases and review of the literature

Authors: Mohamed M. Arnaout, Mina M. Gerges, Matthew D. Cummock, Abad Cherif El Asri, Jeffrey P. Greenfield, Vijay K. Anand, Theodore H. Schwartz

Published in: Acta Neurochirurgica | Issue 8/2019

Abstract

Germ cell tumors are rare malignant tumors frequently located in the suprasellar region. Definitive treatment is chemotherapy and radiation. However, in some circumstances, surgery is indicated for biopsy or resection. There are limited reports of the role of the endonasal endoscopic approach (EEA) in the management of this tumor. We present two cases in which EEA was utilized for successful management of germ cell tumor. The most challenging aspect of germ cell tumor management for the treating physician is knowing the proper indications for surgery. In this paper, we highlight two specific instances, namely diagnosis and tumor refractory to chemoradiation. Given the suprasellar location, EEA is an ideal approach.

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Title: Endonasal surgery for suprasellar germ cell tumors: two cases and review of the literature
Authors: Mohamed M. Arnaout
Mina M. Gerges
Matthew D. Cummock
Abad Cherif El Asri
Jeffrey P. Greenfield
Vijay K. Anand
Theodore H. Schwartz
Publication date: 01-08-2019
Publisher: Springer Vienna
Keyword: Cytostatic Therapy
Published in: Acta Neurochirurgica / Issue 8/2019
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-019-03969-3

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Endonasal surgery for suprasellar germ cell tumors: two cases and review of the literature

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