Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Pediatric and Developmental Pathology
Published in: Pediatric and Developmental Pathology 4/2004

01-04-2004 | Case report

Cytodifferentiation, but Not Resolution, of Embryonal Rhabdomyosarcoma

Author: Kelly Grove Nigro

Published in: Pediatric and Developmental Pathology | Issue 4/2004

Login to get access

Excerpt

A 5-year-old white male with no significant past medical history presented with urinary retention. Computed tomographic (CT) scan showed an intrapelvic mass, 7.1 × 5.9 × 4.7 cm, lying posterior and inferior to the bladder. Needle biopsy of the mass showed a cellular tumor with a heterogeneous cell population consisting of small round blue cells, rhabdomyoblasts with long eosinophilic cytoplasmic tails, and occasional spindle cells in a myxoid background. This appearance, along with strongly positive immunostaining for muscle-specific actin, desmin, and Myo D is consistent with the diagnosis of embryonal rhabdomyosarcoma. …
Literature
1.
Willis, RA 1958The Borderland of Embryology and PathologyButterworth and CoLondon410429
2.
Parham, DM 2001Pathologic classification of rhabdomyosarcomas and correlations with molecular studiesMod Pathol14506514CrossRefPubMed
3.
Parham, DM 1995Small round cell tumors of childhood: importance of cytogenetics in prognosis and diagnosisAdv Pathol Lab Med8223245
4.
Thorner PS, Squire JA (2003) Molecular genetics in the diagnosis and prognosis of solid pediatric tumors. In: Perspectives in Pediatric Pathology. Molecular Mechanisms in Development and in Pediatric Pathology. Augusta, GA: Society for Pediatric Pathology, pp 187–215.
5.
Molenaar, WM, Oosterhuis, JW, Kamps, WA 1984Cytologic “differentiation” in childhood rhabdomyosarcomas following polychemotherapyHum Pathol15973979PubMed
6.
Lowichik, A, Zhou, H, Pysher, TJ, Smith, L, Lemons, R, Coffin, CM 2000Therapy associated changes in childhood tumorsAdv Anat Pathol7341359PubMed
7.
Coffin, CM, Rulon, J, Smith, L, Bruggers, C, White, F 1997Pathologic features of rhabdomyosarcoma before and after treatment: a clinicopathologic and immunohistochemical analysisMod Pathol1011751187PubMed
Metadata
Title
Cytodifferentiation, but Not Resolution, of Embryonal Rhabdomyosarcoma
Author
Kelly Grove Nigro
Publication date
01-04-2004
Publisher
Springer-Verlag
Published in
Pediatric and Developmental Pathology / Issue 4/2004
Print ISSN: 1093-5266
Electronic ISSN: 1615-5742
DOI
https://doi.org/10.1007/s10024-004-1016-x

Other articles of this Issue 4/2004

Pediatric and Developmental Pathology 4/2004 Go to the issue

Original article

Evidence of Oxidative Stress in the Brains of Fetuses with CNS Anomalies and Islet Cell Hyperplasia

Original article

Histopathology of Pediatric Celiac Disease (Response)

Case report

Multifocal Infantile Myofibromatosis and Generalized Fibromuscular Dysplasia in a Child: Evidence for a Common Pathologic Process?

Letter

Fatal Emphysematous Gastritis in a 2-year-old Child with Chronic Renal Failure

Letter to the editor

Histopathology of Pediatric Celiac Disease

Original article

Evaluation of a Protocol for Postmortem Examination of Stillbirths and Neonatal Deaths with Congenital Anomalies