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Published in: BMC Surgery 1/2022

Open Access 01-12-2022 | Cystitis | Case report

Concurrent urachal abscess and florid cystitis glandularis masquerading as malignancy: a case report and literature review

Authors: Yi-Hsuan Chen, Jen-Shu Tseng

Published in: BMC Surgery | Issue 1/2022

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Abstract

Background

The urachus is the embryological remnant of the cloaca and allantois. Failure of its regression can cause diseases any time after birth. It is difficult to differentiate an abscess from urachal adenocarcinoma based on the clinical presentation and image findings. Cystitis glandularis reflects chronic irritation of the bladder urothelium, and tumor-like florid cystitis glandularis can be misdiagnosed as malignancy. We report a patient with concurrent urachal abscess and florid cystitis glandularis which increased the resemblance of malignancy.

Case presentation

A 57-year-old female was incidentally found to have a heterogeneous pelvic mass abutting the urinary bladder. A cystoscopy examination revealed protruding tumors located in the bladder dome. Her blood test results were all normal, and urinalysis showed microscopic hematuria. Urachal cancer was diagnosed and en bloc excision of the umbilicus, tumor, and the involved bladder dome was performed. Pathology revealed urachal abscess with concurrent cystitis glandularis within the urinary bladder. No malignancy was identified in the resected specimen.

Conclusions

It is challenging to distinguish urachal abscess from a malignant tumor based on the clinical presentation and imaging studies. As in our case, the coexistence of urachal abscess and tumor-like florid cystitis glandularis increased the resemblance to a malignancy. This is the first reported case of the concurrence of these two disease entities, and emphasizes that the detection of bladder tumors on cystoscopy is not sufficient to make the diagnosis of urachal cancer with bladder involvement.
Literature
1.
go back to reference Ashley RA, Inman BA, Routh JC, Rohlinger AL, Husmann DA, Kramer SA. Urachal anomalies: a longitudinal study of urachal remnants in children and adults. J Urol. 2007;178(4 Pt 2):1615–8.CrossRef Ashley RA, Inman BA, Routh JC, Rohlinger AL, Husmann DA, Kramer SA. Urachal anomalies: a longitudinal study of urachal remnants in children and adults. J Urol. 2007;178(4 Pt 2):1615–8.CrossRef
2.
go back to reference Parada Villavicencio C, Adam SZ, Nikolaidis P, Yaghmai V, Miller FH. Imaging of the urachus: anomalies, complications, and mimics. Radiographics. 2016;36(7):2049–63.CrossRef Parada Villavicencio C, Adam SZ, Nikolaidis P, Yaghmai V, Miller FH. Imaging of the urachus: anomalies, complications, and mimics. Radiographics. 2016;36(7):2049–63.CrossRef
3.
go back to reference Ninitas P, Anselmo MP, Silva ACE, Ferreira AIS, Santos JF. Urachal abscess mimicking malignant tumor: can imaging tell them apart? Acta Radiol Open. 2019;8(6):2058460119852923.PubMedPubMedCentral Ninitas P, Anselmo MP, Silva ACE, Ferreira AIS, Santos JF. Urachal abscess mimicking malignant tumor: can imaging tell them apart? Acta Radiol Open. 2019;8(6):2058460119852923.PubMedPubMedCentral
4.
go back to reference Lam SW, Linsen PV, Elgersma OE. Infection of previously closed urachus mimicking malignancy: a case report and literature review of radiological findings to the diagnosis. Clin Med Insights Case Rep. 2019;12:1179547619843836.CrossRef Lam SW, Linsen PV, Elgersma OE. Infection of previously closed urachus mimicking malignancy: a case report and literature review of radiological findings to the diagnosis. Clin Med Insights Case Rep. 2019;12:1179547619843836.CrossRef
5.
go back to reference Smith AK, Hansel DE, Jones JS. Role of cystitis cystica et glandularis and intestinal metaplasia in development of bladder carcinoma. Urology. 2008;71(5):915–8.CrossRef Smith AK, Hansel DE, Jones JS. Role of cystitis cystica et glandularis and intestinal metaplasia in development of bladder carcinoma. Urology. 2008;71(5):915–8.CrossRef
6.
go back to reference Tazi F, Ahsaini M, Khalouk A, Mellas S, Stuurman-Wieringa RE, Elfassi MJ, et al. Abscess of urachal remnants presenting with acute abdomen: a case series. J Med Case Rep. 2012;6(1752-1947 (Electronic)):226.CrossRef Tazi F, Ahsaini M, Khalouk A, Mellas S, Stuurman-Wieringa RE, Elfassi MJ, et al. Abscess of urachal remnants presenting with acute abdomen: a case series. J Med Case Rep. 2012;6(1752-1947 (Electronic)):226.CrossRef
7.
go back to reference Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ. Urachal remnant diseases: spectrum of CT and US findings. Radiographics. 2001;21(2):451–61.CrossRef Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ. Urachal remnant diseases: spectrum of CT and US findings. Radiographics. 2001;21(2):451–61.CrossRef
8.
go back to reference Yuksel OH, Urkmez A, Erdogru T, Verit A. The role of steroid treatment in intractable cystitis glandularis: a case report and literature review. Can Urol Assoc J. 2015;9(5–6):E306-9.CrossRef Yuksel OH, Urkmez A, Erdogru T, Verit A. The role of steroid treatment in intractable cystitis glandularis: a case report and literature review. Can Urol Assoc J. 2015;9(5–6):E306-9.CrossRef
9.
go back to reference Yi X, Lu H, Wu Y, Shen Y, Meng Q, Cheng J, et al. Cystitis glandularis: a controversial premalignant lesion. Oncol Lett. 2014;8(4):1662–4.CrossRef Yi X, Lu H, Wu Y, Shen Y, Meng Q, Cheng J, et al. Cystitis glandularis: a controversial premalignant lesion. Oncol Lett. 2014;8(4):1662–4.CrossRef
10.
go back to reference Semins MJ, Schoenberg MP. A case of florid cystitis glandularis. Nat Clin Pract Urol. 2007;4(6):341–5.CrossRef Semins MJ, Schoenberg MP. A case of florid cystitis glandularis. Nat Clin Pract Urol. 2007;4(6):341–5.CrossRef
Metadata
Title
Concurrent urachal abscess and florid cystitis glandularis masquerading as malignancy: a case report and literature review
Authors
Yi-Hsuan Chen
Jen-Shu Tseng
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2022
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-021-01430-w

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