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Published in: European Radiology 1/2016

01-01-2016 | Hepatobiliary-Pancreas

Cystic form of paraduodenal pancreatitis (cystic dystrophy in heterotopic pancreas (CDHP)): a potential link with minor papilla abnormalities? A study in a large series

Authors: M. Wagner, M. P. Vullierme, V. Rebours, M. Ronot, P. Ruszniewski, V. Vilgrain

Published in: European Radiology | Issue 1/2016

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Abstract

Objectives

To analyze the association between cystic dystrophy in the heterotopic pancreas (CDHP) and minor papilla abnormalities.

Material and methods

Seventy-six patients with CDHP were retrospectively included over 14 years. Two radiologists searched for MDCT signs of CDHP (cysts and thickened intestinal wall, inflammatory changes), and minor papilla abnormalities (Santorini duct dilatation, luminal calcifications of the minor papilla). Other pancreatic abnormalities (parenchymal calcifications, main pancreatic duct dilatation) or bile duct dilatation were also analysed.

Results

CDHP was mostly located in the second part of the duodenum (71/76, 93.5 %). Median duodenal wall thickness was 20 mm (range 10–46). There were multiple cysts in 86 % (65/76, median = 3), measuring 2–60 mm. No cysts were identified in four patients (5 %). Inflammatory changes were found in 87 % (66/76). Minor papilla abnormalities were found in 37 % (28/76) and calcifications in the minor papilla without calcifications in the major papilla were only observed in three patients (4 %). Abnormalities of the pancreas and main bile duct dilatation were identified in 78 % (59/76) and 38 % (29/76).

Conclusion

Previously described CT features were seen in most patients with CDHP. However, minor papilla abnormalities were seen in a minority of patients and, therefore, do not seem to be a predisposing factor for CDHP.

Key Points

Imaging features suggesting a CDHP diagnosis are confirmed in a large series.
Minor papilla abnormalities do not seem to be a predisposing factor for CDHP.
Most patients did not have any isolated minor papilla abnormalities.
Literature
1.
go back to reference Potet F, Duclert N (1970) Cystic dystrophy on aberrant pancreas of the duodenal wall. Arch Fr Mal App Dig 59:223–238PubMed Potet F, Duclert N (1970) Cystic dystrophy on aberrant pancreas of the duodenal wall. Arch Fr Mal App Dig 59:223–238PubMed
2.
go back to reference Flejou JF, Potet F, Molas G, Bernades P, Amouyal P, Fekete F (1993) Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognised entity. Gut 34:343–347PubMedCentralCrossRefPubMed Flejou JF, Potet F, Molas G, Bernades P, Amouyal P, Fekete F (1993) Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognised entity. Gut 34:343–347PubMedCentralCrossRefPubMed
3.
go back to reference Kloppel G (2007) Chronic pancreatitis, pseudotumors and other tumor-like lesions. Mod Pathol 20(Suppl 1):S113–S131CrossRefPubMed Kloppel G (2007) Chronic pancreatitis, pseudotumors and other tumor-like lesions. Mod Pathol 20(Suppl 1):S113–S131CrossRefPubMed
4.
go back to reference Adsay NV, Zamboni G (2004) Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis". Semin Diagn Pathol 21:247–254CrossRefPubMed Adsay NV, Zamboni G (2004) Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis". Semin Diagn Pathol 21:247–254CrossRefPubMed
5.
go back to reference Lai EC, Tompkins RK (1986) Heterotopic pancreas. Review of a 26 year experience. Am J Surg 151:697–700CrossRefPubMed Lai EC, Tompkins RK (1986) Heterotopic pancreas. Review of a 26 year experience. Am J Surg 151:697–700CrossRefPubMed
6.
go back to reference Armstrong CP, King PM, Dixon JM, Macleod IB (1981) The clinical significance of heterotopic pancreas in the gastrointestinal tract. Br J Surg 68:384–387CrossRefPubMed Armstrong CP, King PM, Dixon JM, Macleod IB (1981) The clinical significance of heterotopic pancreas in the gastrointestinal tract. Br J Surg 68:384–387CrossRefPubMed
7.
go back to reference Rizzo RJ, Szucs RA, Turner MA (1995) Congenital abnormalities of the pancreas and biliary tree in adults. Radiographics 15:49–68, quiz 147–148 CrossRefPubMed Rizzo RJ, Szucs RA, Turner MA (1995) Congenital abnormalities of the pancreas and biliary tree in adults. Radiographics 15:49–68, quiz 147–148 CrossRefPubMed
8.
go back to reference Dolan RV, ReMine WH, Dockerty MB (1974) The fate of heterotopic pancreatic tissue. A study of 212 cases. Arch Surg 109:762–765CrossRefPubMed Dolan RV, ReMine WH, Dockerty MB (1974) The fate of heterotopic pancreatic tissue. A study of 212 cases. Arch Surg 109:762–765CrossRefPubMed
9.
go back to reference Basili E, Laugier R (2003) Cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 27:1110–1115PubMed Basili E, Laugier R (2003) Cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 27:1110–1115PubMed
10.
go back to reference Pessaux P, Lada P, Etienne S et al (2006) Duodenopancreatectomy for cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 30:24–28CrossRefPubMed Pessaux P, Lada P, Etienne S et al (2006) Duodenopancreatectomy for cystic dystrophy in heterotopic pancreas of the duodenal wall. Gastroenterol Clin Biol 30:24–28CrossRefPubMed
11.
go back to reference Jouannaud V, Coutarel P, Tossou H et al (2006) Cystic dystrophy of the duodenal wall associated with chronic alcoholic pancreatitis. Clinical features, diagnostic procedures and therapeutic management in a retrospective multicenter series of 23 patients. Gastroenterol Clin Biol 30:580–586CrossRefPubMed Jouannaud V, Coutarel P, Tossou H et al (2006) Cystic dystrophy of the duodenal wall associated with chronic alcoholic pancreatitis. Clinical features, diagnostic procedures and therapeutic management in a retrospective multicenter series of 23 patients. Gastroenterol Clin Biol 30:580–586CrossRefPubMed
12.
go back to reference Fekete F, Noun R, Sauvanet A, Flejou JF, Bernades P, Belghiti J (1996) Pseudotumor developing in heterotopic pancreas. World J Surg 20:295–298CrossRefPubMed Fekete F, Noun R, Sauvanet A, Flejou JF, Bernades P, Belghiti J (1996) Pseudotumor developing in heterotopic pancreas. World J Surg 20:295–298CrossRefPubMed
13.
go back to reference Rebours V, Levy P, Vullierme MP et al (2007) Clinical and morphological features of duodenal cystic dystrophy in heterotopic pancreas. Am J Gastroenterol 102:871–879CrossRefPubMed Rebours V, Levy P, Vullierme MP et al (2007) Clinical and morphological features of duodenal cystic dystrophy in heterotopic pancreas. Am J Gastroenterol 102:871–879CrossRefPubMed
14.
go back to reference Vullierme MP, Vilgrain V, Flejou JF et al (2000) Cystic dystrophy of the duodenal wall in the heterotopic pancreas: radiopathological correlations. J Comput Assist Tomogr 24:635–643CrossRefPubMed Vullierme MP, Vilgrain V, Flejou JF et al (2000) Cystic dystrophy of the duodenal wall in the heterotopic pancreas: radiopathological correlations. J Comput Assist Tomogr 24:635–643CrossRefPubMed
15.
go back to reference Procacci C, Graziani R, Zamboni G et al (1997) Cystic dystrophy of the duodenal wall: radiologic findings. Radiology 205:741–747CrossRefPubMed Procacci C, Graziani R, Zamboni G et al (1997) Cystic dystrophy of the duodenal wall: radiologic findings. Radiology 205:741–747CrossRefPubMed
16.
go back to reference Andrieu J, Palazzo L, Chikli F, Doll J, Chome J (1989) Cystic dystrophy on aberrant pancreas. Contribution of ultrasound-endoscopy. Gastroenterol Clin Biol 13:630–633PubMed Andrieu J, Palazzo L, Chikli F, Doll J, Chome J (1989) Cystic dystrophy on aberrant pancreas. Contribution of ultrasound-endoscopy. Gastroenterol Clin Biol 13:630–633PubMed
17.
go back to reference Hall TC, Dennison AR, Garcea G (2012) The diagnosis and management of Sphincter of Oddi dysfunction: a systematic review. Langenbecks Arch Surg 397:889–898CrossRefPubMed Hall TC, Dennison AR, Garcea G (2012) The diagnosis and management of Sphincter of Oddi dysfunction: a systematic review. Langenbecks Arch Surg 397:889–898CrossRefPubMed
18.
go back to reference Stolte M, Weiss W, Volkholz H, Rosch W (1982) A special form of segmental pancreatitis: "groove pancreatitis". Hepatogastroenterology 29:198–208PubMed Stolte M, Weiss W, Volkholz H, Rosch W (1982) A special form of segmental pancreatitis: "groove pancreatitis". Hepatogastroenterology 29:198–208PubMed
19.
go back to reference Itoh S, Yamakawa K, Shimamoto K, Endo T, Ishigaki T (1994) CT findings in groove pancreatitis: correlation with histopathological findings. J Comput Assist Tomogr 18:911–915CrossRefPubMed Itoh S, Yamakawa K, Shimamoto K, Endo T, Ishigaki T (1994) CT findings in groove pancreatitis: correlation with histopathological findings. J Comput Assist Tomogr 18:911–915CrossRefPubMed
20.
go back to reference Adsay NV, Basturk O, Klimstra DS, Kloppel G (2004) Pancreatic pseudotumors: non-neoplastic solid lesions of the pancreas that clinically mimic pancreas cancer. Semin Diagn Pathol 21:260–267CrossRefPubMed Adsay NV, Basturk O, Klimstra DS, Kloppel G (2004) Pancreatic pseudotumors: non-neoplastic solid lesions of the pancreas that clinically mimic pancreas cancer. Semin Diagn Pathol 21:260–267CrossRefPubMed
21.
go back to reference Chatelain D, Vibert E, Yzet T et al (2005) Groove pancreatitis and pancreatic heterotopia in the minor duodenal papilla. Pancreas 30:e92–e95CrossRefPubMed Chatelain D, Vibert E, Yzet T et al (2005) Groove pancreatitis and pancreatic heterotopia in the minor duodenal papilla. Pancreas 30:e92–e95CrossRefPubMed
22.
go back to reference Levenick JM, Gordon SR, Sutton JE, Suriawinata A, Gardner TB (2009) A comprehensive, case-based review of groove pancreatitis. Pancreas 38:e169–e175CrossRefPubMed Levenick JM, Gordon SR, Sutton JE, Suriawinata A, Gardner TB (2009) A comprehensive, case-based review of groove pancreatitis. Pancreas 38:e169–e175CrossRefPubMed
23.
go back to reference Triantopoulou C, Dervenis C, Giannakou N, Papailiou J, Prassopoulos P (2009) Groove pancreatitis: a diagnostic challenge. Eur Radiol 19:1736–1743CrossRefPubMed Triantopoulou C, Dervenis C, Giannakou N, Papailiou J, Prassopoulos P (2009) Groove pancreatitis: a diagnostic challenge. Eur Radiol 19:1736–1743CrossRefPubMed
24.
go back to reference Kalb B, Martin DR, Sarmiento JM et al (2013) Paraduodenal pancreatitis: clinical performance of MR imaging in distinguishing from carcinoma. Radiology 269:475–481CrossRefPubMed Kalb B, Martin DR, Sarmiento JM et al (2013) Paraduodenal pancreatitis: clinical performance of MR imaging in distinguishing from carcinoma. Radiology 269:475–481CrossRefPubMed
Metadata
Title
Cystic form of paraduodenal pancreatitis (cystic dystrophy in heterotopic pancreas (CDHP)): a potential link with minor papilla abnormalities? A study in a large series
Authors
M. Wagner
M. P. Vullierme
V. Rebours
M. Ronot
P. Ruszniewski
V. Vilgrain
Publication date
01-01-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 1/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-3799-8

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